schizophrenia paper 3 Flashcards
define schizophrenia
it is a psychotic mental health disorder where the person has contact with their reality and insight. An example is psychosis. Schizophrenia is where a person looses touch with their reality and has a distorted view of the world.
It is most commonly diagnosed within men than women and it is also noticed more within the cities than the countryside. In the working class rather than the middle class.
it interferes severely with everyday tasks hence why people are hospitalised or even homeless.
define and explain one positive symptom of Schizophrenia
positive symptoms of schizophrenia= Atypical symptoms experienced in addition to normal experiences. This includes hallucinations and delusions.
Hallucinations= it is an unusual sensory experience and are perceptions which occur without stimuli from the external world. Some hallucinations are related to events within the environment whereas others bear no relationship to what the senses are picking from the environment. People could see distorted facial expressions or occasionally people or animals that are not there.
Types of hallucinations:
1) Auditory would involve hearing voices. The voice is usually someone persecuting, threatening or criticising.
2) Visual is where the person sees someone evil or the devil.
3) Visual and auditory occur together and are the most common.
4) sematic is where they think insects are eating away at them.
Define and explain another positive symptom of schizophrenia
Delusions= it is known as a paranoia and irrational belief. Ideas and beliefs or values they believe are true but are highly unlikely to be true. People with delusions believe they are under external control and Delusions can make a person with schizophrenia behave in ways that make sense to them but are perhaps bizarre to others. Most of these individuals are not aggressive and are in fact more likely to be victims than preparators of violence some can lead to aggression.
Types of Delusions:
1)Delusion of persecution- false belief that friends, family, government or work people are plotting against them,
2)Delusions of reference= false belief that random events are meaningful patterns of events.
3)Delusions grandeur= False belief that one has special power and are famous.
4)Delusions being controlled= False belief that thoughts, feelings, and behaviours are controlled by stronger force.
Speech disorganisation:
Abnormal thoughts process where the individual has problems with organising their thoughts which would show up their speech. They may slip from one topic to another or mid- sentence and extreme cases their speech may be incoherent and sound like gibbersih.
Define negative symptoms of schizophrenia
Negative symptoms of schizophrenia= Atypical experiences that represent the loss of usual experience such as clear thinking or normal levels of motivation.
Speech poverty = changes in pattern of speech and involves reduce frequency and quality of speech.
Reduction= the amount of quality speech which involves a delay in the sufferers verbal response in a conversation.
They made produce fewer words in a given time on a task of verbal frequency and they would not be able to spontaneously produce them.
Sometimes, it causes delays within people’s conversation and their responses
define the second negative symptom of schizophrenia and an explanation
negative symptoms= involves the loss of usual abilities and experiences.
Avolition= This is called apathy. It involves loss of motivation to carry out tasks and results in lowered activity levels.
It can be described as finding it difficult to begin with or keep up with goal directed activity.
People with Schizophrenia have reduced motivation to carry out a range of activities.
main symptoms:
loss of energy and general loss of interest in life showing a lack of motivation.
poor hygiene and grooming
unable to finish goal/ tasks- a levels
social isolation and withdrawal
define classification of mental disorder/ Schizophrenia
classification in mental disorders= the process of organising symptoms into categories based on which symptoms cluster together in people with mental disorders.
Two major systems of Classification:
1) The world health organisations international classifications of disease edition (ICD-10)
two or more negative symptoms are sufficient for diagnosis
Recognises subtypes of Schizophrenia - Catatonic
2) American psychiatric association’s diagnostic and statistical manual edition 5(DSM-V)
one of the positive symptoms are sufficient for diagnosis
Does not recognise subtypes of Schizophrenia
define dopamine
a neurotransmitter that has a excitatory effect and is associated with the sensation of pleasure. Unusually high levels are associated with schizophrenia and unusually low levels are associated with Parkinson disease.
what are the five different sub-types of schizophrenia?
1) Disorganised= symptoms include disorganised and vague speech bizarre behaviour absence of emotion, social withdrawal and loss of interest of everyday life activities.
2)Catatonic= excessive motor activity (repeating everything or copying movements of others) and the opposite still/silent.
3)paranoid= powerful delusions and hallucinations are common. Delusions are magnificent or persecution.
4) undifferentiated= a mixture of the symptoms above categories. Some symptoms may be a form of all categories.
5) Residual= People who have suffered from extreme or major symptoms of Schizophrenia but now display mild symptoms. Some may suffer from social withdrawal, bizarre thoughts.
what is the evaluation of Diagnosis and Classification of Schizophrenia ?
Limitation= Inter-rater reliability is the extent to which different accessors agree with each other about the same assessments. In the case of diagnosis this means to the extent of two or more diagnosis for the same individuals. Ellie Cheniaux et al - two psychiatrists independently diagnose 100 patients using DSM and ICD. One psychiatrists diagnosed 26 with Schizophrenia according DSM and 44 from the ICD and the other one diagnosing 13 with DSM and 24 with ICD. This shows there is very low agreement in Diagnosis, lack inter-rater reliability and criterion validity from psychiatrists and this means it could lead to misdiagnosis.
limitation= Co-morbidity refers to the medical condition and how common it is. It also refers to that two or more condition occur together. if conditions occur together this calls in question the validity of the diagnosis and classification as there might just a single condition.
Buckley concluded that half of the patients with a diagnosis of schizophrenia also have a diagnosis of depression 50%, 47% substance abuse and 29% of ptsd and 23% with OCD. This is a limitation as patience are likely to be mis diagnosed and have the wrong treatment and which could affect recovery time and prolong health issues.
limitation= cultural bias in diagnosis
African Americans and English people of Afro- Caribbean origin are several times more likely than British people to be diagnosed with schizophrenia. One issue with positive symptoms shows that things like hearing voices in African cultures would be seen as more acceptable than British cultures or even communications exists within certain cultures. This shows the culture bias within diagnosis as shows there is a lack of validity and psychiatrists may over diagnose people as they are not familiar with cultural norms and traditions within that group and this is a limitation people who are ill are diagnosed unnecessarily.
define genetics
Genes contain DNA strands. DNA produces instructions for general physical features of an organism (eye colour, height) and also specific physical features. It known as neurotransmitter levels and size of brain structures) these may impact on psychological features such intelligence and mental disorder and they are transmitted from parents or offspring.
define neural correlates
patterns of structure or activity in the brain that occur in conjunctions with an experience and may be implicated in the origins of that experience.
The Genetic basis of schizophrenia
Schizophrenia runs in the family and could in the genes. there are systematic investigations of the extent where there is genetic similarity between family members associated with the likelihood of both developing schizophrenia,. For example, we share 100% of our genes with an identical twin, 50% with sibling or parent. There is a strong relationship between the genetic similarity and shared risk of schziophrenia findings from Gottesman’s large scale family study.
what are candidate gene?
Individual genes are believed to be associated with risk of inheritance. Because a number of genes each appear to confer a small increased risk of schizophrenia which is polygenic so it requires different combinations. Because different combinations have identified different candidate genes shows it is a heterogynous gene. Stephen Ripke et al carried out a huge study combining all previous data from genome-wide studies of schizophrenia. The genetic make-up of 37,000 people diagnosed with Schizophrenia was compared to 113,000 controls; 108 genetic variations were associated with increased risk of schizophrenia. Genes associated with increased risk included those coding for the functioning of a number of neurotransmitters including dopamine.
what is the dopamine hypothesis?
neurotransmitters= the brain’s chemical messengers appear to work differently in the brain of a person with a schizophrenia. Dopamine is widely believed be involved. Dopamine is important in the functioning brain systems that may be implicated in the symptoms of schizophrenia.
Hyperdopaminergia in the subcortex= The orginial version of dopamine hypothesis focused on the possible role of high levels or activity of dopamine in the subcortex i.e the central areas of brain. For example, an excess of dopamine receptors in a Broca’s area which is responf
Hyperdopaminergia in the subcortex= The orginial version of dopamine hypothesis focused on the possible role of high levels or activity of dopamine in the subcortex i.e. the central areas of brain. For example, an excess of dopamine receptors in a Broca’s area which is responsible for speech production and may be associated with speech poverty or the experience of auditory hallucinations.
Hypodopamingeria in the cortex
More recent versions of dopamine hypothesis have focused on abnormal dopamine systems in the brain’s cortex. Goldman Rakic have identified a role of low levels of dopamine in the prefrontal cortex (responsible for thinking or decision making in the negative symptoms of schizophrenia. It may be hyper or hypodomingeria are the right explanations for high and lows levels of dopamine affecting the regions of schizophrenia.
what is the neural correlates of schizophrenia ?
Neural correlates are measurements of the structure or functions of the brain that correlate with an experience in the case of schizophrenia. Both negative and positive symptoms have neural correlates.
what are neural correlates of negative symptoms?
One negative symptom avolition involves loss of motivation. Motivation involves the anticipation of a reward and regions of the brain like the ventral striatum in schizophrenia are involved in anticipation and the development of avolition. Juckel et al has measured activity levels in the ventral stratum in schizophrenia. They observed a negative correlation between activity levels in the ventral stratum.
what is the neural correlates of positive symptoms?
Allen scanned the brain of people experiencing auditory hallucinations and compared them to a control group as they identified pre-recorded speech as theirs or others. Lower activation levels in superior temporal gyrus and anterior cingulate gyrus were found in the hallucination group who also made more errors than the control group and there was reduced activity in the neural correlate causing auditory hallucinations.
what is the evaluation of biological explanations of schizophrenia?
strength= there is evidence with people from the gottesman study of genetic similarity and shared risk of schizophrenia. The adoption studies by peeka children that are from families of the disorder are more likely to inherent it even if they have been adopted to a family with no history of schizophrenia and Ripke showed that people who showed that some people are more vulnerable to getting disorders.
strength= sources for abnormal dopamine functioning in schizophrenia. Dopamine agonists like amphetamines that increase the level of dopamine make schizophrenia worse and produce schizophrenia like symptoms in people not diagnosed with schizophrenia. Antipsychotic drugs work by reducing dopamine activity. Both drugs were seen as important in schizophrenia. Radioactive labelling studies found chemicals needed to produce are taken up faster in the brains of people.
limitations= these brain symptom experiments leave questions unanswered like does the brain cause unusual activity in the region of the brain to cause the symptom. there may be a correlation between the levels of activity in the ventral striatum in causing negative symptoms.