schizophrenia GL

Question 1

Risperdal dosing

Answer 1

start 0.5-1
increase by 0.5-1 Q3D
target 2-6
max 8

Question 2

Olanzapine dosing

Answer 2

start 5-10
increase by 2.5-5 Q3D
target 10-20
max 20

Question 3

Quetiapine dosing

Answer 3

start 100
increase by 100 QD
target 300-800
max 800

Question 4

clozapine dosing

Answer 4

start 12.5-25
increase by 12.5-25 Q2D
target 300-600
max 900

Question 5

ariprprazole target

Answer 5

10-30

Question 6

ziprazidone target

Answer 6

80-160

Question 7

paliperidone target

Answer 7

3-15

Question 8

chlorpromazine target

Answer 8

300-1000 acute
300-600 maintenance
all typicals should be equivalent to this

Question 9

chlorpromazine equivalent for haldol and loxamine

Answer 9

100 chlorpromazine=10 loxapine=2 haldol

Question 10

haldol target

Answer 10

acute 6-20

maintenance 6-12

Question 11

FEP dosing

Answer 11

lower half of dose range except quetiapine: 500-600 mg needed

Question 12

difference between maintaining FGA and SGA

Answer 12

lower dose of FGA needed than acute

same dose of SGA needed as acute

Question 13

PORT approved psychosocial Tx (8)

Answer 13

FamilyTx
CBT
ACT
SUD
Wt mx
Token economy
supported emplyment
skills training

Question 14

psychosocial Tx with insufficient evidence acc to PORT

Answer 14

Peer intervention
cognitive remediation
interventions to increase adherence
special tx for FEP

Question 15

what to start in FEP?

Answer 15

CPA and texas: SGA except clozapine

PORT: FGA or SGA except clozapine and olanzapine

Question 16

what to start in MEP?

Answer 16

CPA and texas: SGA except clozapine

PORT: FGA or SGA except clozapine

Question 17

To start routine anticholinergic acc to PORT?

Answer 17

not for SGA

case by case for FGA

Question 18

neuromodulatoin in PORT?

Answer 18

rTMS rec for persistent positive sx
ECT=antipsychotics, not evidence it’s better for Tx resistance.
ECT is an augmentaion to clozapine acc to Texas