Schizophrenia and Psychotic Disorders Flashcards

1
Q

Psychosis definition?

A

An inability to distinguish between symptoms of delusion, hallucination and disordered thinking from reality
Lack of insght

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2
Q

Clinical presentation of psychosis?

A

Hallucinations

Delusional beliefs

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3
Q

Definition of delusion?

A

An unshakeable idea or belief which is out of keeping with the person’s social and cultural background

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4
Q

Examples of delusion?

A

Grandiose
Paranoid (persecutory)
Hypochondrial
Self referential

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5
Q

Most common cause of psychosis?

A

Schizophrenia

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6
Q

Epidemiology of schizophrenia?

A

1 per 100 population
M:F equal
Age of onset 15-35

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7
Q

Positive symptoms of schizophrenia?

A

Hallucinations
Delusions
Disordered thinking

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8
Q

Negative symptoms of schizophrenia?

A

Apathy
Lack of interest
Lack of emotions

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9
Q

For diagnosis of schizophrenia, at least one of…?

A
TAPP
Thought disorder
Auditory hallucinations
Passivity phenomenon
Delusional 'P'erceptions
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10
Q

For diagnosis of schizophrenia, and/or at least two of…?

A

Persistent hallucinations
Breaks or interpolations in the train of thought
Catatonic behaviour
“Negative” symptoms

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11
Q

Potential biological factors implicated in schizophrenia?

A

Obstetric complications
Maternal influenza
Winter birth
Substance misuse

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12
Q

Potential social and psychosocial factors implicated in schizophrenia?

A

Occupation and social class
Migration
Social isolation
Life events as precipitants

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13
Q

Differential diagnosis for schizophrenia?

A

Delirium or acute organic brain syndrome
Depressive episode with psychotic symptoms
Manic episode with psychotic symptoms
Schizoaffective disorder

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14
Q

Delirium?

A

Prominent visual experience, hallucination and illusions
Affect of terror
Persecutory delusions
Fluctuating, worse at night

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15
Q

Depressive episode with psychotic symptoms?

A

Delusions of guilt, worthlessness and perception

Derogatory auditory hallucinations

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16
Q

Manic episode with psychotic symptoms?

A

Delusions of grandeur, special powers or messianic roles

Gross overactivity, irritability and behavioural excitement

17
Q

Management of schizophrenia?

A
Treat early
Antipsychotic
Clozapine in treatment resistance
CBT
Family intervention
18
Q

Prognosis and recovery figures in schizophrenia?

A

80% after a first episode
Up to 50% have a moderate recovery
Small group with chronic symptoms and little recovery

19
Q

Good prognostic factors for schizophrenia?

A
Prompt treatment
Acute onset
Absence of family history
Clear precipitant
Good premorbid function
Mood disturbance
Maintenance of initiative, motivation
20
Q

Poor prognostic factors for schizophrenia?

A

Slow, insidious onset
Childhood onset
Prominent negative symptoms

1.6x higher mortality
9x suicide risk
Shorter life expectancy