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306(2): Psychiatry > Schizophrenia > Flashcards

Schizophrenia Flashcards

1
Q

First rank symptoms

A
  1. Auditory hallucinations
    - Running commentary/ thought echo/ secondary
  2. Passivity phenomena
    - Idea that body is being controlled externally
  3. Thought disorder
    - Insertion/ withdrawal/ broadcast.
  4. Delusion perceptions
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2
Q

Diagnosis of schizophrenia

A

Must have at least 2 of the following for 1 month, with continuous 6 month period affecting function.
At least one must be positive

  • Auditory hallucination
  • Thought disorder
  • Other hallucinations
  • Catatonia
  • Negative symptoms
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3
Q

Examples of negative symptoms

A

Avolition

Anhedonia

Impoverishment of speech

Flattening of affect/ blunting

Attention deficit.

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4
Q

Management of schizophrenia

A
  1. Atypical antipsychotic
    - Risperidone, olanzapine, quetiapine, aripiprazole
  2. Olanzapine

Consider typical if atypical do not work

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5
Q

Steps for starting antipsychotic medication

A
  1. Atypical antipsychotic at an effective doser
    - Olanzapine, risperidone, quetiapine
  2. Low potency first-generation antipsychotic
    - Chlorpromazine
    - Increase dose to reach clinical effect
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6
Q

List the EPS effects

A

Dystonia

Parkinsonism

Akathisia

Tremor

Tardive dyskinesia

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7
Q

______ can be used to treat parkinsonism caused by antipsychotics

A

Procylidine

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7
Q

______ can be used to treat parkinsonism caused by antipsychotics

A

Procylidine

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8
Q

examples of depot antipsychotics

A

Paliperidone

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9
Q

examples of depot antipsychotics

A

Paliperidone

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10
Q

Adverse effects of risperidone

A

Prolactinaemia

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11
Q

Adverse effects of risperidone

A

Prolactinaemia

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12
Q

Adverse effects of clozapine

A

Agranulocytosis (most fatal)

Hypersalivation

Constipation

Increased seizure risk

Postural hypotension

Myocarditis

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13
Q

Treatment resistance psychosis is defined as…

A

Failure to respond to maximum dose of at least 2 antipsychotics over 8 weeks
- At least 1 must be atypical

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14
Q

Investigations before starting antipsychotics

A

FBC, U+Es, Prolactin

Lipids

ECG

BMI

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14
Q

______ can be given for the management of severe neuroleptic malignant syndrome

A

Amantidine and IV fluids

15
Q

Features of neuroleptic malignant syndrome

A

Muscle breakdown and stiffness (raised CK, AKI)

Muscle tremors

Hyperthermia

Hypertension, tachycardia

15
Q

Adverse effects of aripriprazole

A

Most common (in first 2-3 weeks)
- Akathisia
- Insomnia

306(2): Psychiatry (9 decks)

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