Schizophrenia Flashcards
What are the positive symptoms of SZ?
Hallucinations - unusual sensory events
Delusions - irrational beliefs and paranoia
What are the negative symptoms of SZ?
Avolition - finding it hard to begin or keep up with goal directed activity
Speech poverty - changes in speech, lack fluency, quality and quantity of speech reduced
What affects the validity of classification?
Gender bias
Symptom overlap
What affects the reliability of classification?
Cultural differences
Co morbidity
What is symptom overlap
People with dissociative identity disorder actually have more SZ symptoms than those diagnosed with SZ
What is co- morbidity?
Another disorder is accompanied with SZ
What is the original dopamine hypothesis ?
An excess of dopamine in certain regions of the brain is associated with the positive symptoms of SZ.
Messages from neutrons that transmit dopamine fire too easily or too often, which leads to hallucinations and delusions
What is the revised dopamine hypothesis?
The symptoms of dopamine are caused by excess of dopamine in the subcortical areas of brain, particularly in the Mesolimbic pathway.
The negative symptoms of SZ are thought to arise deficit of dopamine in areas of the prefrontal cortex .
Evaluate the biological approach of SZ?
Reductionist - explained SZ in terms of just one gene or the action of one neurotransmitter
Deterministic
Socially sensitive - people with SZ family members may get upset
Practical implications - dopamine hypothesis
Dopamine abnormalities are not present in all people with SZ
What are typical antipsychotics used for?
Used primarily to combat the positive symptoms of SZ
How do typical antipsychotics work?
Typical antipsychotics bind to dopamine receptors and block its action.
In order for the pathways to be blocked a similar number of D2 receptors in the other areas of the brain must also be blocked causing undesirable side effects
What are atypical antipsychotics used for?
Combat positive symptoms but they are are also claimed to have beneficial effects on negative symptoms
How do atypical antipsychotics work?
Temporarily occupy the D2 receptors and rapidly dissociate to allow normal dopamine transmission
Evaluate biological treatment for SZ
Effectiveness - less relapse rate than placebo
Ethics - in extreme cases they are forced to take the drug, even if it is against their will
Appropriateness - requires little motivation and is relatively fast acting. Means it is good for patients who need urgent attention
Side effects - typical antipsychotics can cause movement problems
What are the 3 aspects of family dysfunction?
- high levels of arguments
- difficulty communicating with each other
- parents being excessively critical and controlling of their children