schizo Flashcards
What agents have high risk of QT prolongation?
chlorpromazine
thioridazine
haloperidone
ziprasidone
iloperidone
What agents have high metabolic risk?
olanzapine
clozapine
risperidone
paliperidone
quetiapine
What agents should you use if metabolic risk is a concern?
aripiprazole
ziprasidone
lurasidone
asenapine
What agents lower seizure threshold?
clozapine
chlorpromazine
What agents may cause insomnia?
aripiprazole, brexpiprazole
What agents may cause dizziness?
asenapine
iloperidol
brexpiprazole
cariprazole
What agents may cause impulsivity?
aripiprazole
What agents are prolactin-elevating?
FGAs
risperidone
paliperidone
olanzapine
What agents have anticholinergic effects?
chlorpromazine
thioridazine (highest)
clozapine
olanzapine
What agents have highest EPS?
haloperidol
fluphenazine
At high doses, which SGAs have EPS?
risperidone
paliperidone
Smoking has drug interaction with
olanzapine
clozapine
(reduces levels via CYP1A2)
Antacids have drug interaction with
(reduce absorption of) chlorpromazine
What has interactions with olanzapine-samidorphan?
3A4, 1A2, opioid withdrawal/dependence
What has interactions with lumateperone?
3A4
risperidone LAI frequency
2 weeks
paliperidone (Invega Sustenna) LAI frequency
1 month
paliperidone (Invega Trinza) LAI frequency
3 months
paliperidone (Invega Hafyera) LAI frequency
6 months
aripiprazole (Abilify Maintena) LAI frequency
1-2 months
aripiprazole (Aristada) LAI frequency
1-2 months