Schildklier, bijnier Flashcards

1
Q

Struma

A

Vergrote schildklier

Jodiumdeficientie

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2
Q

Nodus

A

50% > 50 jarigen

5% kwaadaardig

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3
Q

Klachten nodus

A

Heesheid
Drukkend gevoel platliggen
Passage en slikklachten
Zwelling lymfeklieren in hals

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4
Q

Papillair schildkliercarcinoom

A

Beste prognose

Tyreoectomie met radioactief jodium

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5
Q

Folliculair schildkliercarcinoom

A

Goede prognose
Thyreoectomie met radioactief jodium
Metasteert naar botten en longen

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6
Q

Medullair schildkliercarcinoom

A

Slechtere prognose
Erferlijk
Thyreoectomie, bij metastasen TK-remmers

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7
Q

Anaplastisch schildkliercarcinoom

A

Slechste prognose

Als mogelijk is thryeoectomie anders bestraling

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8
Q

NFkB

A

Upregulatie D2 promotor

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9
Q

IL-1, IL-6 en TNF-alpha

A

Afname D1

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10
Q

Thyereotrope as

A

Hypothalamus: TRH
Hypofyse: TSH
Perifeer: T3, T4

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11
Q

Gondadotrope as

A

Hypothalamus: GnRH
Hypofsye: LH/FSH
Perifeer: oestradiol, testosteron

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12
Q

Somatotrope as

A

Hypothalamus: GHRH
Hypofyse: GH
Perifeer: IGF-1

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13
Q

Corticotrope as

A

Hypothalamus: CRH
Hypofyse: ACTH
Bijnieren: cortisol

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14
Q

Dexamethason suppressie test

A

Zou bij gezond persoon voor daling cortisol zorgen

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15
Q

Addison crise symptomen

A

Misselijkheid en duizeligheid
Malaise
Verminderde eetlust
Orthostatische hypotensie

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16
Q

Zona reticularis

A

Androgene steroidhormonen

Binnenste van bijnier

17
Q

Zona fasciculata

A

Cortisol

Middelste bijnier

18
Q

Zona glomerulosa

A

Aldosteron

Buitenste bijnier