SBAs Flashcards
She has undergone a transcervical resection of fibroid , which agent should be used to prevent
intrauterine adhesions?
Hyaluronan gel
An 83 year old lady found to have gross ascites with an ovarian mass.
Which is the physiological process responsible for her ascites?
. Increased permeability of capillaries / exudative ascites - high in protein -
( and lymphatic
flow markedly decreases to levels as low as 15 ml per hour )
Which is the physiological process responsible for Nonmalignant ascites ?
increase in production of fluid and the lymphatic system
reaches capacity with flow rates of 200 ml of ascites per hour ( transudative ascites )- low in protein -
Which bariatric surgery is a malabsorptive procedure?
Roux-en-Y gastric bypass
Which factors has good evidence that bariatric surgery improves them ,
& Which has a paucity of evidence?
Good evidence:
Success rate of IVF
Resolution of PCOS rate
Maternal outcome
Fetal outcome
NOT : Miscarriage rate
A 60 year old woman is experiencing post menopausal bleeding. Her
BMI is 45.
Which type of cancer she is at risk of?
endometrioid endometrial cancer
she is found to have endometrioid endometrial cancer.BMI=42 , The MRI scan confirms the malignancy to be confined to the one half of the myometrium.
What is the first line of management for her?
Its FIGO Stage 1B
Laparoscopic hysterectomy + Bilateral salpingo-oophorectomy ( due to high BMI)
56 year old woman undergoes total abdominal hysterectomy for fibroid uterus. What are the steps for enhancing recovery ?
1- clear fluid allowed up to 2 hours prior to surgery,
2- avoiding long acting sedative
3- administration of antibiotic prior to incision
4- Thromboprophylaxis ♥️♥️
5- decreasing the volume of intravenous fluid with early feeding
How many women in UK are diagnosed with cervical cancer annually before the age of 45?
1000
. A 26 year old diagnosed with squamous cell cancer of the cervix. She is nulliparous. She has a 2cm tumour on her cervix.What should be the appropriate management?
Radical vaginal trachelectomy
( 2 cm is the upper limit of diameter to do this procedure)
A 34 year old is diagnosed CIN3 on colposcopy and CIN2 on cervical punch biopsy. She is adamant that she wants an ablation technique rather than an excision. What is the reason, why she will not be suitable for an ablation method.?
Her entire transformation zone is not visible
( there is no major discrepancy between the cytology and histology both high grade)
What is the depth/length of the tissue that should be removed in transformation zone
(TZ) type 1 /2 /3 ?
Type 1 at least 7mm (<10mm)
type 2 : 10 – 15mm
Type 3 :15- 25mm
A 27 year old is diagnosed with CIN1 and is on regular colposcopic monitoring. She is now 13 weeks pregnant. What should be her management?
🩷🩷Colposcopy should be performed now
A pregnant woman should have colposcopy in late first trimester or early 2nd
trimester for an abnormal cytology.
A 41 year old lady has been diagnosed with estrogen positive breast cancer. She is 16 weeks pregnant at present.What should be the management?
Systemic Chemotherapy can be given to this patient
1- Systemic chemotherapy is safe in the 2nd trimester of pregnancy but contraindicated in the 1st trimester of pregnancy
2- Radiotherapy & Tamoxifen is
contraindicated until delivery.
3- Breast surgery is considered safe in all trimesters of pregnancy without any risk to the fetus.
A 38 year old lady has been diagnosed with ER negative breast
cancer. She received adjuvant chemotherapy. She is planning to
conceive .
What should be the plan for further management?
🩷🩷ECHO should be performed in pregnancy to detect cardiomyopathy 🩷🩷
1- should wait at least 2 years after treatment, which is when the risk of cancer recurrence is highest.
2- there aren’t any increase in congenital malformations or stillbirth
among the offspring
3- Echocardiography should be performed during pregnancy in women at risk to detect cardiomyopathy
4- fertility is affected by treatment
When to deliver the baby if the mother is on chemotherapy sessions for breast cancer?
birth should be more than 2–3 weeks after the last chemotherapy session
What are the Considerations about lactation during treatment for breast Cancer?
- Women should not breastfeed when taking trastuzumab or tamoxifen or chemotherapy
For how long Women on tamoxifen are advised to stop this treatment before trying to conceive?
3 months
What advice should be given to women planning pregnancy following metastatic breast cancer?
should be advised against a further
pregnancy
What is the Impact of pregnancy on risk of recurrence of breast Cancer?
can be reassured that long-term survival after breast cancer is not adversely affected by pregnancy
🔱 The impact of pregnancy does not seem to be modified by tumour characteristics (e.g. size,
hormone receptor status)
What advice should be given to women wishing to breastfeed following treatment for
breast cancer?
they can breastfeed from the unaffected breast
What is the effect of adjuvant chemotherapy of breast Cancer on fertility ?
Chemotherapy-induced gonadotoxicity may cause permanent amenorrhoea with complete loss
of germ cells
What is the effect of adjuvant hormonal of breast Cancer therapy on fertility?
there is no evidence that it
impairs fertility, but pregnancy is not advised during treatment
What is the risk of endometrial hyperplasia without atypia progressing to endometrial cancer ?
<5% over 20 years
What should the first-line medical treatment of hyperplasia without atypia be?
for a minimum of 6 months :
1- The LNG-IUS should be the first-line medical treatment ( lower regression rate )(encouraged to retain the
for up to 5 years)
2- Continuous progestogens ( medroxyprogesterone 10–20 mg/day or
norethisterone
10–15 mg/day)
🛑 Cyclical progestogens should not be used because they are less effective in inducing regression of
endometrial hyperplasia without atypia
How should the follow-up for a patient with hyperplasia without atypia be?
At minimum of 6-monthly intervals
At least two consecutive 6-monthly negative biopsies should be obtained prior to discharge
What are the risk factors for relapse hyperplasia without atypia ? How to follow up the patients with those risks?
1- body mass index (BMI) of 35 or greater
2-those treated with oral progestogens
🩷 6-monthly endometrial biopsies are recommended. Once two
consecutive negative endometrial biopsies have been obtained then long-term follow-up should be
considered with annual endometrial biopsies
When is surgical management appropriate for women with endometrial hyperplasia without atypia?
- should not be considered as a first-line treatment
- is indicated in :
1-women not wanting to preserve their fertility
2-progression to
atypical hyperplasia occurs during follow-up
3-there is no histological regression of hyperplasia
despite 12 months of treatment
4-there is relapse of endometrial hyperplasia after completing
progestogen treatment
5-there is persistence of bleeding symptoms
6-the woman declines
to undergo endometrial surveillance or comply with medical treatment.
What is the role of Endometrial ablation in the management of endometrial hyperplasia without atypia?
not recommended
What should the initial management of atypical hyperplasia be?
should undergo a total hysterectomy by laparoscopic approach
🛑 There is no benefit from intraoperative frozen section analysis of the endometrium or routine
lymphadenectomy.
How should women with atypical hyperplasia who wish to preserve their fertility or who are not
suitable for surgery be managed?
Pretreatment investigations ( Histology, imaging and tumour marker results) to rule out invasive endometrial cancer or co-existing ovarian
cancer
♥️ First-line treatment with the LNG-IUS should be recommended, with oral progestogens as a
second-best alternative
How should women with atypical hyperplasia not undergoing hysterectomy be followed up?
endometrial biopsy every 3 months until two consecutive negative biopsies are obtained
long-term follow-up with endometrial
biopsy every 6–12 months is recommended until a hysterectomy is performed.
How should endometrial hyperplasia be managed in women wishing to conceive?
Disease regression should be achieved on at least one endometrial sample before women attempt to
conceive.
🔱 Assisted reproduction may be considered as the live birth rate is higher and it may prevent relapse
compared with women who attempt natural conception.
Which HRT preparations is suitable for Women with endometrial hyperplasia?
continuous
combined HRT preparation ( not sequential HRT preparation)
Or continuous progestogen intake using the LNG-IUS
What is the risk of developing endometrial hyperplasia on adjuvant treatment for breast cancer?
tamoxifen : increased risks of developing endometrial
hyperplasia and cancer.
aromatase inhibitors (such as anastrozole, exemestane and letrozole) : are not known to increase the risk of endometrial hyperplasia and
cancer
Should women on tamoxifen be treated with prophylactic progestogen therapy?
its routine use cannot be recommended
(The effect of the LNG-IUS on breast cancer recurrence
risk remains uncertain)
How should women who develop endometrial hyperplasia while on tamoxifen treatment for breast
cancer be managed?
1- The need for tamoxifen should be reassessed
2-management should be according to the histological
classification of endometrial hyperplasia
A 50 year old woman complains of menorrhagia.
The gold standard investigation for her is:
Hysteroscopy & Endometrial Biopsy
What size of hysteroscope should be used in the outpatient setting?
2.7mm hysteroscope with 3 – 3.5mm sheath
Do analgesics given before diagnostic outpatient hysteroscopy ?
Routine use of opiate analgesia should be avoided
should be advised to consider taking (NSAIDs) around 1 hour before
Does cervical preparation reduce uterine trauma in case of outpatient hysteroscopy?
should not be used in
the absence of any evidence of benefit
* Prostaglandin administration has no benefit in postmenopausal
women
What are the contraindications of Prostaglandins ?
1-uncontrolled asthma,
2-chronic adrenal failure,
3-acute porphyria,
4-renal or hepatic
impairment
5- breastfeeding
What is the difference between rigid & flexible hysteroscopes in the outpatient setting?
- Flexible : less pain
- rigid : provide better
images/ fewer failed procedures / quicker examination time / reduced cost
Which uterine distension medium should be used during outpatient hysteroscopy?
carbon dioxide or normal saline : neither is superior in reducing pain
normal saline : 1- reduce the incidence of vasovagal episodes.
2- improved image quality
3- hysteroscopy to be completed more quickly
4- it’s required when using bipolar electrosurgery
choose the best distention medium that will reduce her risk of
having vasovagal attack in outpatient hysteroscopy ?
Normal Saline
Should routine dilatation of the cervical canal be used before insertion of the hysteroscope
in an outpatient setting?
No , should be avoided
unnecessary in the majority of procedures
Should topical local anaesthetic be administered before outpatient hysteroscopy?
1- does not reduce pain during the procedure
2- may reduce the incidence of vasovagal reactions
3- should be considered where
application of a cervical tenaculum is necessary.
Should injectable local anaesthetic be administered to the cervix and/or paracervix before outpatient
hysteroscopy?
routine administration , particularly in:
1- postmenopausal women.
2- where
larger diameter hysteroscopes are being employed (outer diameter greater than
5mm)
3-need for cervical dilatation : (e.g. cervical stenosis).
What are the benefits of injectable local anaesthetic before outpatient
hysteroscopy?
reduction of the pain
🛑 is not
indicated to reduce the incidence of vasovagal reactions
Should conscious sedation be used to reduce pain associated with outpatient hysteroscopic procedures?
should not be routinely used
1 Does a vaginoscopic approach to outpatient hysteroscopy reduce pain and increase the feasibility of the
procedure?
Yes,& should be the standard technique for outpatient hysteroscopy where blind endometrial biopsy is not required
What should be the angle at which the primary trocar is inserted in diagnostic laparoscopy ?
90° to the skin
She was admitted for ectopic
pregnancy and needs laparoscopic salpingectomy. She gives history of previous midline laparotomy for bowel surgery.
What would be the best method for verress needle insertion?
Palmer’s point entry ( unless there is history of splenic surgery)
Hasson (open entry) technique can also be used
What is The rate of adhesion formation at the umbilicus following midline laparotomy?
& following low transverse incision ?
50% following midline laparotomy
23% following low transverse incision
A 21 year old young woman is booked for diagnostic laparoscopy for
chronic pelvic pain. Her BMI is 19.
Her highest risk of complication is:
Vascular injury
in very thin woman the aorta only lies 2.5cm away from the umbilicus
A woman is booked in for marsupialization of bartholin’s cyst. She is
being brought into theatre after having an anesthetic.
The following should be checked as per the WHO surgical checklist
🌸 Patient specific concern
What should be checked prior to induction on anesthesia as per the WHO surgical checklist?
Allergy status
If the risk of ovarian cyst being malignant at age of 46 y is
1:1000.
What would be the risk of malignancy when she turns 50?
3:1000
The risk of ovarian malignancy increases by threefold after the age of 50
What is the incidence of chemical peritonitis after laparoscopic ovarian cystectomy for dermoid cyst ?
0.2% - rare -
What blood tests should be performed in the assessment of women with ovarian masses?
👉 CA-125 assay does not need to be undertaken in all premenopausal women
👉 (LDH), α-FP and hCG should be measured in all women under age 40 with a
complex ovarian mass because of the possibility of germ cell tumours.
What is the single most effective way of evaluating an ovarian mass ?
transvaginal
ultrasonography
What is the role of the routine use of CT & (MRI) in the assessment of suspected ovarian masses?
does not improve the sensitivity or specificity obtained by transvaginal ultrasonography
What is the best way to estimate the risk of malignancy of ovarian masses?
Risk of Malignancy Index (RMI) is the most widely used model
serum CA-125 (CA-125); menopausal status (M); and ultrasound
score (U).
RMI = U x M x CA-125
What is the failure risk of hysteroscopic sterilization?
2 in 1000 - uncommon
A 65 year old lady is diagnosed with epithelial ovarian cancer
confined to the fallopian tube and ovary.
Her 5-year survival rate is:
80- 95%
after chemotherapy
A woman with Stage 1 ovarian cancer. What should
She have as first line management.
?
Staging surgery with Retroperitoneal lymph node assessment
🛑 Systemic retroperitoneal lymphadenectomy should not be done if it is confined to the ovaries
. A staging laparotomy for ovarian cancer involves the following:
1_Laparotomy +2- TAH +3- BSO +4- Infracolic Omentectomy +5- Biopsies of
peritoneal deposit + 6-Biopsy of pelvic & abdominal peritoneum +
7-retroperitoneal lymph node assessment
A 59 year old lady is diagnosed with high risk Stage 1c Ovarian
cancer (Grade 3)
She is offered adjuvant chemotherapy with:
6 cycles of carboplatin
The 2nd line drug
would be paclitaxel.
What is The FIGO staging of endometrial cancer the histology confirms that the tumour invades
the serosa.?
Stage IIIA
( Serosa or adnexa)
What is The FIGO staging of endometrial cancer the histology confirms that the tumour invades cervical stroma ?
Stage II
What is The FIGO staging of endometrial cancer the histology confirms that the tumour invades the vagina ?
Stage IIIB
( Vagina or parametrium )
What is The FIGO staging of endometrial cancer the histology confirms that the tumour invades pelvic lymph nodes?
Stage IIIC1
What is The FIGO staging of endometrial cancer the histology confirms that the tumour invades paraaortic lymph nodes ?
Stage IIIC2
What is The FIGO staging of endometrial cancer the histology confirms that the tumour invades bladder or bowel?
Stage 4 A
What is The FIGO staging of endometrial cancer the histology confirms that the tumour invades inguinale lymph nodes or distanct metastases?
Stage 4 B
What percentage of vulval cancer has association with lichen sclerosis?
33%
Which lymph node excision has the lowest morbidity in the management of vulval cancer ?
Sentinel node biopsy
What are The disadvantages of having a midline incision for ovarian surgery?
🌸Wound dehiscence risk is higher🌸
slow to enter the abdomen
it is not cosmetically best for the patient
What is The advantage of having a midline incision for ovarian surgery?
1- least hemorrhagic
2- least nerve damage than lower transverse incision.
What are the characteristic of the Mersilene tape for cervical suture ?
1- a braided suture ( not monofilament )
2- high tensile strength 🌸
3- low tissue
reaction
4- non- absorbable suture
Which material should the suprapubic catheter be made of to reduce complications?
100% silicone
What is the contraindication for suprapubic catheterization following a gynaecological surgery?
🩷 Anticoagulation therapy for blood clotting disorder
and if a pelvic mass is present.
What is The approximate incidence of fistula formation in laparoscopic gynaecological surgery complicated by bladder injury ?
5 %
What is the ureteric injury rates
at laparoscopic gynaecological surgery ?
from <1% to 2%
What is the method should be used for repair The injury in the
upper 1/3rd of the ureter laparoscopic gynaecological surgery ?
Uretero-ureterostomy
What is the method that should be used for repair an injury at
the middle third of the ureter happened during laparoscopic gynaecological surgery ?
uretero-ureterostomy as first choice
trans-uretero-ureterostomy (end-to-side anastomosis) - should
not be used as a first-line
What is the method that should be used for repair an injury at the lower third of the ureter happened during laparoscopic gynaecological surgery ?
uretero-neocystostomy (re-implantation of the ureter into
the bladder) should be preferred.
A 54 year old sustained bladder injury during laparoscopic assisted
vaginal hysterectomy. She had the catheter for 2 weeks. Prior to
removal of the catheter she needs:
Retrograde cystography
If contrast escape is noted then the
catheter should be left in situ and the test repeated in 1 week.
How can Most bladder injuries be sutured ?
in one or two layers
using a 2-0 or 3-0 absorbable suture (such as polyglactin)
A running non-locked repair with the sutures placed 0.5 to
1 cm apart and 0.5 to 1 cm lateral to the cystotomy angles
A 54 year old sustained bladder injury during laparoscopic assisted vaginal hysterectomy.what is the incidence of fistula formation ?
5%
What is the method that should be used for repair an injury at the lower third of the ureter in case of shortened ureter,?
psoas hitch or a Boari
flap
If fistula is suspected after labroscopic bladder injury, how to make the diagnosis?
Micturating cystourethogram
A 65 year old lady is having debulking surgery for ovarian cancer.
Excision of external iliac nodes was carried out. 2 months later, she presented with paraesthesia over mons pubis and labia.
Which nerve injury did she sustain during the surgery?
Genitofemoral Nerve
When performing hysteroscopy with a 30°
hysteroscope in a retroverted uterus. What should be the
position of the cervical os on view for appropriate hydrodilatation?
12 o’clock with the light cable up
When performing hysteroscopy with a 30°
hysteroscope in a antroverted uterus. What should be the
position of the cervical os on view for appropriate hydrodilatation?
6 o’clock with the light cable down
When performing hysteroscopy with a 0
hysteroscope , What should be the
position of the cervical os on view for appropriate hydrodilatation?
Central
A diagnosis of ruptured ectopic pregnancy is made and the decision for laparoscopy +/- salpingectomy is made. After discussion with her mother, she refuses to consent for the procedure
The Court of Protection could be approached as:
Her refusal is not valid as she is influenced by her mother
The validity of consent is based on 3 factors what are they ?
capacity, information and free will.
What are The ECG changes that may suggest pulmonary embolism ?
S wave in lead 1; Q wave in lead 3, Inverted T wave in lead 3
S1Q3T3
She presents with a pelvic mass. She also complains of hirsutism and voice change. Her testosterone level is 9nmol/L.
which type of ovarian tumor she is suspected to have?
Leydig cell tumor
In the risk reporting system in gynaecology. The Following incident need not be included in the trigger list:
Blood loss of 400mls during hysterectomy ( on ≥ 500mls)
In the risk reporting system in gynaecology. The Following incident need be included in the trigger list:
1-Delayed diagnosis of ectopic pregnancy
2-Pneumothorax during laparoscopy
3- Unplanned admission to ITU
4- Conflict between surgeons regarding management of case
Every trust should have a risk management team for a particular
specialty.
The following personnel need not be part of a gynaecology risk team ?
MDT Coordinator
Who should be part of a gynaecology risk team ?
A. Consultant Gynaecologist
B. Ultrasonographer
C. Theatre Practitioner
D. Service Manager
E. lead gynaecology nurse
When performing an audit on the outcome of Group B streptococcus infection in Obstetric patients.
She should be proceeding in the following sequence:
A. Identify a standard, Collect data to assess performance, Implement the changes if there is any, Collect data to determine whether care has been improved
The statistical test to compare two sets of observations on a single sample
would be:
. Wilcoxon matched pairs test
A study is designed to compare the age “distribution “ in patients
presenting with ectopic pregnancy. The null hypothesis is that there is
no difference in the age groups of women presenting with ectopic
pregnancy.
The appropriate statistical test is:
X2 test
🪙🪙💰
A researcher wants to measure the incidence of angular pregnancy.
The following research methodology should be used:
Longitudinal descriptive study
A researcher wants to obtain evidence of association of exposure of
pregnant women to passive smoking and the outcome.
The following research method is appropriate:
Randomised controlled study