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Respiratory > Sarcoidosis > Flashcards

Sarcoidosis Flashcards

1
Q

Common SBA Stem

A

Black
Female
20-40 years old

Bilateral hilar lymphadenopathy
Arthralgia
Erythema Nodosum

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2
Q

Sarcoidosis

A

Chronic multi-system disease, characterised by non caseating granulomas

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3
Q

Sarcoidosis - Primary symptom

A

SOB

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4
Q

Sarcoidosis - Lungs

A

Interstitial Lung Disease (Pulmonary Fibrosis)

Granulomas

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5
Q

Sarcoidosis - Liver (20% of patients)

A

Hepatitis
Liver nodules
Liver cirrhosis
Cholestasis

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6
Q

Sarcoidosis - Eyes (20% of patients)

A

Uveitis
Conjuctivitis
Glaucoma

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7
Q

Sarcoidosis - Skin involvement (15% of patients)

A

1) Erythema nodosum - tender red nodules on shins
2) Lupus Pernio - raised purple lesions across nose and cheeks
3) Granulomas in scar tissue

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8
Q

Sarcoidosis - Heart (5% of patients)

A

Inflammation (pericarditis/myocarditis)

Arrythmia (LBBB/RBBB)

Restrictive cardiomyopathy (granuloma in heart stops it filling properly)

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9
Q

Sarcoidosis - CNS (5% of patients)

A

Nodules in brain
Encephalitis
Diabetes insipidus

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10
Q

Sarcoidosis - PNS (5% of patients)

A

Bell’s Palsy

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11
Q

Sarcoidosis - Clinical Symptoms

A

Cough
SOB
Uveitis

Hypercalcaemia
Pericarditis - sharp chest pain that is relieved by sitting forward

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12
Q

Sarcoidosis Complications

A

Pulmonary Fibrosis

Cor Pulmonale

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13
Q

Lofgren’s Syndrome

A

Specific acute sarcoidosis presentation:

  1. Erythema Nodosum
  2. Arthralgia
  3. Bilateral hilar lymphadenopathy
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14
Q

Sarcoidosis Differentials

A 
TB 
Lymphoma 
EAA 
HIV 
Toxoplasmosis
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15
Q

Sarcoidosis Diagnosis

A

Raised serum ACE
Raised calcium
Raised IL 2 Receptors

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16
Q

Sarcoidosis CXR

A

Bilateral Hilar Lymphadenopathy -> Pulmonary Fibrosis

17
Q

Sarcoidosis CT

A

Hilar Lymphadenopathy

Pulmonary nodules

18
Q

Sarcoidosis MRI

A

Can rule out CNS involvement

19
Q

Sarcoidosis PET Scan

A

Can show active areas of inflammation

20
Q

Other investigations

A 
U and Es (kidneys)
Urine A:C and dipstick (nephritis) 
LFTs (hepatitis) 
Opathamology review
ECG and Echocardiogram 
USS Abdo
21
Q

No/mild symptoms management

A

No treatment

22
Q

Sarcoidosis management

A

6-24 months of steroids (+ Bisphosphonate cover)

Methotrexate/Azathioprine

Respiratory (9 decks)

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