Sarcoidosis

Question 1

What is the definition of Sarcoidosis?

Answer 1

• Autoimmune disorder

- Multi system granulomatous disorder of unknown cause

Question 2

What are the features of granulomas in Sarcoidosis?

Answer 2

Non caseating granulomas

Question 3

What is the incidence of ‘Sarcoidosis’

Answer 3

1. African american female

2. Previous infection with TB

Question 4

Name 3 general symptoms of ‘Sarcoidosis’

Answer 4

1. Fever
2. Weight loss
3. Fatigue
4. Uveitis / Conjunctivitis

Question 5

Name 2 lower respiratory symptoms of ‘Sarcoidosis’

Answer 5

1. Bihilar lymphadenopathy

2. Midzone fibrosis

Question 6

Name 3 GI symptoms of ‘sarcoidosis’

Answer 6

1. Hepatomegaly
2. Splenomegaly
3. Pancreatitis

Question 7

Name 3 Renal symptoms of ‘sarcoidosis’

Answer 7

1. Hypercalcaemia
2. Hyperuricaemia
3. Kidney stones

Question 8

Name 3 dermatological symptoms of ‘sarcoidosis’

Answer 8

1. Erythema nodosum - painful red nodules on shins
2. Lupus pernio - raised, dark purpule papules on nose, cheek and fingers
3. Athralgia

Question 9

What is ‘lofgren’s syndrome’

Answer 9

Acute form of sarcoidosis characterised by ;

1. Bihilar lymphadenopathy
2. Erythema nodosum
3. Polyathralgia
4. swinging fever