Sarcoidosis Flashcards
1
Q
What are the features of sarcoidosis?
A
erythema nodosum, bilateral lymphadenopathy, swinging fever, SOB (pulmonary fibrosis), malaise, weight loss
2
Q
What are the investigations for sarcoidosis?
A
raised serum ACE hypercalcaemia raised ESR and CRP spirometry (restrictive defect) tissue biopsy (non caseating granulomas)
3
Q
What is primary tuberculosis?
A
someone who is exposed to TB for the first time
the initial lesion (ghon complex) usually heals by fibrosis. those who are immunocompromised may develop disseminated miliary TB
4
Q
What is secondary tuberculosis?
A
a person who is immunocompromised who develops re-activation of the infection
generally occurs in the apex of the lungs
5
Q
Where are the extra-pulmonary infection sites of TB?
A
CNS (tuberculous meningitis) Pott's disease (vertebral bodies) cervical lymph nodes renal GI tract
6
Q
What investigations can you use to diagnose TB?
A
Mantoux test
ziehl-nelson staining
interferon-gamma blood test
7
Q
What is the treatment of active TB?
A
'RIPE' for first 2 months rifampicin isoniazid pyrazinamide ethambutol
