Sarcoidosis Flashcards
What is sarcoidosis
Non-caseating granuloma
What symptoms do you get
Pulmonary symptoms:
- dry cough, young-middle aged women
Extrapulmonary manifestations:
Erythema nodosum
Every other organ
Arthralgia on walking
Lupus pernio - purple rash on face
Non caseating granuloma meaning
Non-caseating = no infective debris in the middle of the granuloma
What might you get in the kidneys
High calcium - nephrocalcinosis; kidney stones
Other differentials
HIV
Toxoplasmosis
TB
Two key findings for sarcoidosis
ACE
High calcium
Other scans done besides CT
PET scan
Management of sarcoidosis
Oral pred
What do you give alongside steroids
PPIs
Do FRAX score, DEXA scan and then
Second line management of sarcoidosis
Dmards - methotrexate
Etanacerpt - TNF alpha
Final treatment if steroids don’t work
Lung transplant
