Saq Randoms Flashcards

1
Q

Disease where disease is different depending on mother/father inheritance and how it works?

A

Prader willi- maternal genes imprinting

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2
Q

5 signs of downs

A

Epicanthic folds, brushfield spots in eye, wide sandle gap, single palmar crease, flat occiput

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3
Q

Test to confirm downs

A

Karyotyping

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4
Q

3 tests in jaundice-
1haem
1 biochem
1microbio

A

Haem-haemoglobin
Biochem-bilirubin
Microbio-urine culture

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5
Q

3 classes of drugs other than dmards used in rheumatoid arthritis

A

Steroid, nsaid, antitnf (infliximab)

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6
Q

Sensation loss longterm after Ramsay Hunt called?

A

Post Herpetic Neuralgia

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7
Q

Major risks for Tretinoin?

A

Suicidality
Teratenogenic for women-need longterm contraceptive

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8
Q

Worse spots for prognosis for SCC

A

Lip and ear

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9
Q

Acne bacteria name

A

Popriobacterium. Acne

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10
Q

Ramsay hunt on nose sign called?

A

Hutchinson sign

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11
Q

Dye used in opthalm

A

Florescin

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12
Q

Casseating lesion
Non casseating lesion

A

Cass-TB
Non-Sarcoid

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13
Q

Important information with Steroids

A

Don’t stop suddenly

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14
Q

Sleep apnoea score

A

Epworth questionnaire

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15
Q

Sleep apnoea treatment

A

Cpap

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16
Q

Cor pulmonale signs on ecg

A

Right axis deviation

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17
Q

Af options to reestablish rhythm

A

Dc flecanide amiodarone

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18
Q

Enzyme simvastatin limits

A

HMGCOA

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19
Q

Bug for endocarditis
IV drug user bug

A

Strep viridans
Staph aureus

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20
Q

Diagnosis criteria for endocarditis

A

DUKE

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21
Q

Eye complication/sign endocarditis

A

Roth spots

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22
Q

Atrial fib ecg

A

Irregular Irregular
Tachy
Absent p waves

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23
Q

Atypical depression

A

Catatonic

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24
Q

Causes of infertility

A

Fibroids
Cervical failure
Pcos
Antiphospholid

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25
Q

Reiters triad in reactive arthritis

A

Can’t pee see climb tree
Urethritis Conjunctivitis arthritis

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26
Q

Ank Spondylitis signs in xray

A

Bamboo spine

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27
Q

Long term comps of parkinsons meds

A

On off fluctuations
Dyskenisia

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28
Q

Treatment options for postural hypotension

A

Fludrocortisone
Midodrine

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29
Q

Investigation for hypermesis gravidarum

A

Urine dip for ketones

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30
Q

Airway securing for unstable neck injury?

A

Jaw thrust
Chin lift contraindicated

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31
Q

Septic arthritis bugs

A

Staph aureus-generally
Gonorrhea-young people

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32
Q

Airway adjuncts

A

I gel-supraglottic
Nasopharyngeal
Guedel-oropharyngeal

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33
Q

Nikoskys sign

A

Layers crumble apart in Derm conditions such as
Pemphigus vulgaris
Stephen Johnson/Toxic epidermal necrolysis
Scalded skin sydrome

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34
Q

Psoriasis treatment

A

Emollient
Vit d
Steroids
Methotrexate

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35
Q

Why use Pen5 in tonsillitis

A

Doesn’t cause rash in mono
Which is possible differential of tonsilitis

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36
Q

Lymphoma mechanism

A

Malignant proliferation of b cells

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37
Q

Diabetic retinopathy treatment

A

Anti-VGEF
Panretinal photocoag

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38
Q

Abdomen space for metasteses

A

Peritoneum

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39
Q

Vaginal exam signs endometriosis

A

Tender uterus
Enlarged ovaries

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40
Q

Genetic mutation in ovarian cancer

A

Braca 1 and 2

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41
Q

Risk factors for ovarian cancer

A

Early menarche
Late menopause
Nulliparity

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42
Q

Primary vs secondary infertility

A

Primary-never been pregnant
Secondary-have been before but can’t now

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43
Q

Dermoid cyst origin

A

Germ cells

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44
Q

Checks in infertility

A

Fsh lh 21 day progesterone

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45
Q

Risk to newborn of gest diabetes mother

A

Hypoglycemia

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46
Q

4 lobes of liver

A

Right left caudate quadrate

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47
Q

Ligament of liver

A

Falciform

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48
Q

Hepatocellular carcinoma tumour marker

A

AFP-alphafetoprotein

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49
Q

Bile contains

A

Bile salts
Cholesterol
Phospholipids

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50
Q

Rfs for gallstone

A

Forty fat female fertile fair

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51
Q

Small vs Large bowel obstruction

A

Small- pain higher up, less distension, vomitting more common

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52
Q

Ileus vs mechanical obstruction sign

A

Tinkling-mechanical
Absent-ileus

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53
Q

Marker in pancreatitis

A

Lipase
Amylase too but less accurate

54
Q

Early comps of pancreatitis

A

Shock Sepsis DIC

55
Q

Long term comps of pancreatitis

A

Pancreatic necrosis, abscess, chronic pancreatitis

56
Q

Spleen action of Red and White pulp

A

Red- filter RBC
White- acts as lymphoid tissue

57
Q

Splenectomy longterm management of infection risk

A

Lifelong prophylactic antibiotics
Vaccinations

58
Q

Why Appendicitis pain moves

A

Starts in lif due to visceral pleura
Moves to rif when parietal pleura involved

59
Q

Stomach blood supply

A

Foregut-Celiac
Midgut-Sup Mesenteric
Hindgut-Inf Mesenteric

60
Q

Dermatomyositis
Red knuckles
Purple eyelids
Antibodies

A

Rk-gottrons papules
Pe-heliotrope
Jo1,ANA

61
Q

Scleroderma features

A

Calcinisosis-Calcium deposits in skin
Oesophagus issues
Sclerodactly
Telangectasia

62
Q

Sle antibodies

A

ANA, anti-dsDNA,anti-smith

63
Q

Sle issues

A

Livedo reticularis-Web wash
Coag defects
Thrombocytopenia
Antiphospholipd

64
Q

Test for blood type in babies/pregnancy

A

Direct Coombs test

65
Q

Resp distress syndrome causes

A

Prematurity
Diabetes
History of irds

66
Q

Cells produce surfactant

A

Type 2 pneumocytes

67
Q

Resp distress xray sign

A

Ground glass appearance

68
Q

Complex febrile seizure characterised by

A

Duration 15 mins
2 in 24 hrs
Incomplete recovery within the hour

69
Q

Intersussception mechanism

A

Bowel telescopes into other bit of bowel

70
Q

Intersussception treatments

A

Air insufflation
Laparoscpic surgery- if perforated, peritonitic, failed enema

71
Q

Acute vs chronic leukemia

A

Acute-immature blast cells
Chronic-mature white cells

72
Q

Treatment of CML

A

Imatinib oral
Tyrosine kinase inhibitor

73
Q

Bone pain in All/aml

A

Bone marrow infiltration

74
Q

Supportive treatment for chemo/stem cells

A

Transfusions for anaemia/low platelets
Prophylactic antibiotics
Counselling on diagnosis

75
Q

Haemoglobin cut off for transfusion

A

70

76
Q

Massive blood transfusion definition

A

Total blood transfused
10 units=total body blood volume

77
Q

Macrocytic 2 categories and examples

A

Megaloblastic-b12 folate
Non-meg-alcohol, hypothyroidism

78
Q

Pernicious anaemia testing

A

Parietal cell antibody

79
Q

Pernicious anaemia treatment

A

IM hydroxycobalamin (B12 injection)

80
Q

Swollen trapped leg diagnosis and treatment

A

Compartment syndrome
Fasciotomy

81
Q

Normal length
PR
QRS
QT

A

PR- 200
QRS- 100
QT-450

82
Q

Common CF infections

A

Staph aureus
Pseudomonas aeruginosa

83
Q

Cuases of bronchiectasis

A

CF Measles Pneumonia Tuberculosis

84
Q

Parkinson plus syndromes

A

Prog supranuclear palsy
Multi system atrophy
Corticobasal degen
Lewy body dementia

85
Q

Causes of parkinsons

A

Idiopathic
Drug induced
Parkinson plus syndromes

86
Q

Sites of absorption for b12 folate iron

A

IFB
Iron-duodenum
Folate-jejunum
B12-ileum

87
Q

3 inner ear parts

A

Vestibule cochlear semicircular canals

88
Q

Menieres prophylaxis

A

Betahistine

89
Q

SLE signs and symptoms

A

Fatigue joint pain weight loss malar rash lymphadenopathy hepatomegaly

90
Q

Comps of SLE

A

Anaemia lupus nephritis

91
Q

Gi bleed scores
Pre scope to assess severity
Post scope

A

Pre Blatchford
Post rockall

92
Q

Emergency treatment life threatening asthma attack

A

Oxygen 15l
5mg neb salbutomol
40mg oral prednisolone

93
Q

Osteopenia vs osteoporosis

A

T score -1 to -2.5

94
Q

Most common rectal cancer

A

Adenocarcinoma

95
Q

Blood marker for colorectal cancer

A

Cea- carcinoembryonic antigen

96
Q

Dangerous metabolic abnormality in rhabdomyolysis

A

Hyperkalaemia

97
Q

Menieres disease prophylaxis

A

Betahistine

98
Q

How is a fractured nof position/presented?

A

Abducted externally rotated and shorter limb

99
Q

Trigeminal neuralgia investigation

A

Mri head

100
Q

Trigeminal neuralgia treatment

A

Carbamazepine
Trigeminal nerve block

101
Q

Coarc of artoa symptoms

A

Weak pulses peripherally
Radio fem delay

102
Q

Sickle cell advise to reduce issues

A

Avoid dehydration cold
Avoid alcohol and smoking

103
Q

Pkd can cause what neuro complication

A

SAH

104
Q

How is antivgef given

A

Intravitreal injections

105
Q

How to treat legionella

A

Clarirthromycin

106
Q

Pencil in cup deformity associated with

A

Psoriatic arthritis

107
Q

Abnormal bloods in tumour lysis
And prevention med of tumour lysis

A

High K and phos
Low calcium
Allopurinol

108
Q

Blue vision drug cause

A

Blue pill-viagra

109
Q

Inf mono complications

A

Splenic rupture
Chronic fatigue

110
Q

Optic neuritis treatment

A

High dose Steroids

111
Q

Treatment of acute angle closure glaucoma

A

Laser iridotomy

112
Q

Mirizzi syndrome

A

Common hepatic duct obstruction
Compression from stone in cystic duct

113
Q

Cushing reflex

A

Hypertension bradycardia irregular breathing

114
Q

Stone formation most likely locations

A

Pelvic to ureter
Ureter to bladder
Pelvic brim

115
Q

Common renal stone composition

A

Calcium oxalate

116
Q

Pneumothorax signs

A

Resonance
Reduced breath sounds
Asymmetry of chest expansion

117
Q

Chest Drain location

A

Pecs lats 5th intercostal

118
Q

Amenorrhea
Primary vs secondary causes

A

Primary- Androgen insensitivity imperforate hymen
Secondary-Cushings Premature ovarian failure

119
Q

Pcos criteria score

A

Rotherdam

120
Q

Causes of glomerulonephritis

A

Post strep
Iga nephrop
Membranous nephrop

121
Q

Nephritis symptoms

A

Haematuria oliguria

122
Q

Lung and kidney problems caused by which condition

A

Good pastures antigbm

123
Q

Treatment of hypercalcaemia

A

IV Saline Fluids
Bisphosponates

124
Q

Quinsy unable to open mouth mechanism

A

Pus spasms pterygoid muscle

125
Q

Quinsy treatment

A

IV Fluids and analgesia
IV penicillin and metronidazole

126
Q

Analysis on exudate fluid

A

Micro, culture and sensitivity
Cytology

127
Q

Miscarriage treatment

A

Ergometrine-stop the bleeding
Anti D if rh Neg
Analgesia
Mifepristone/misopirstol

128
Q

Contraindicated drugs for Pregnancy in the 3rd trimester (late)

A

Nsaids-close ductus arteriosus
Ssris and nitrofurantoin

129
Q

Crystal composition
Gout
Pseudogout

A

Gout-monosodium urate
Pesudo-calcium pyrophosphate

130
Q

Lung and liver problems

A

A1AT disease diagnosed via liver biopsy

131
Q

Lead time vs length time

A

Lead time- don’t survive longer cos diagnosed earlier
Length time-shorter diseases less likely to be picked up

132
Q

Bradford Hill causality

A

Strength
Dose
Temporality
Reversibility
Consistency