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Sample Questions Flashcards

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1
Q

Osteoma M?F

A

M>F

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2
Q

How can you differentiate between an osteoma and a torus?

A

Torus does not grow

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3
Q

What are the features of Gardner’s Syndrome?

A 
epidermoid/sebaceous cysts
fibromas
impacted and supernumerary teeth
osteomas
premalignant intestinal polyps
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4
Q

Do osteomas contain tooth structure?

A

can contain odontogenic remnants, tooth structures, and osteodentin

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5
Q

What is the origin of ossifying fibromas?

A

PDL cells

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6
Q

What is the most common location of ossifying fibromas?

A

mandible posterior to the canine

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7
Q

Ossifying fibroma M?F

A

F>M

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8
Q

Aggressive form of ossifying fibroma

A

juvenile active ossifying fibroma

can cause bone expansion

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9
Q

Symptoms of ossifying fibroma

A

asymptomatic

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10
Q

Radiographic features of ossifying fibroma

A

marble shaped

lytic lesion with radiopaque foci

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11
Q

Ossifying fibroma resembles what radiographically?

A

fibrous dysplasia

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12
Q

Osteoblastoma M?F

A

M>F

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13
Q

Symptoms of osteoblastoma

A

progressively growing painful lesion
may cause expansion of cortical plates
tender on palpation

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14
Q

Most common site of osteoblastoma

A

molar and premolar areas of the mandible

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15
Q

Pathologic features of osteoblastoma

A

vascular stroma
trabeculae of osteoid and immature bone
trabeculae rimmed with active proliferating fibroblasts

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16
Q

What is the main difference between an osteosarcoma and an osteoblastoma?

A

cartilage may be present in osteosarcoma, not in osteoblastoma
malignant osteoid present in osteosarcoma

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17
Q

Age predilection of osteosarcoma

A

10-25y

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18
Q

Most common site of osteosarcoma

A

mandible

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19
Q

Symptoms of osteosarcoma

A

mass, lump, or swelling

pain, paresthesia, nasal obstruction, nose bleeds

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20
Q

Describe the bone present in an osteosarcoma

A

immature, thin, not well mineralized

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21
Q

What are the 2 pathologic features necessary to characterize lesion as an osteosarcoma

A

malignant tumor osteoid and cytologically malignant cells

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22
Q

What are the most common metastasis sites for osteosarcoma?

A

lung and cervical lymph nodes

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23
Q

Does a chondrosarcoma contain tumor osteoid?

A

No, but does contain fully developed cartilaginous structures

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24
Q

What are the symptoms of chondrosarcoma?

A

expansion, loose teeth, nasal discharge

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25
Chrondrosarcoma radiographic features
cotton wool calcifications thick walled radiolucency possibly widened PDL space
26
Which is more common in the jaws, a chondrosarcoma or a mesenchymal chondrosarcoma?
mesenchymal chondrosarcoma
27
Fibrosarcoma mandible?maxilla
mandible>maxilla
28
Symptoms of fibrosarcoma
mass or swelling | pain, paresthesia, trismus
29
Fibrosarcoma can clinically be confused for...
SCC | salivary gland tumor
30
Fibrosarcoma affects teeth how?
can move teeth | root erosion
31
Histologically, what bone tumor resembles a cross section of cable wire or fish swimming upstream?
fibrosarcoma
32
What are 2 syndromes associated with Langerhans cell histiocytosis?
Hand-Schuller-Christian syndrome | Letere-Siwe syndrome
33
In Langerhans cell histiocytosis, langerhans cells migrate from ? to ? to ?
from bone marrow to skin to lymph nodes
34
Chronic focal LCH M?F and age?
M>F | children and young adults
35
Chronic disseminated LCH characterized by
multifocal granulomas skull lesions exophthalmos diabetes insipidus
36
Acute disseminated LCH age predilection
infants
37
Radiographic features of LCH
teeth float in air | skull lesions punched out
38
LCH may mimic what in children (oral)?
juvenile periodontitis
39
Age predilection of central giant cell granuloma
children and young adults
40
Central giant cell granuloma M?F
F>M
41
Most common location of central giant cell granuloma
anterior mandible
42
Will a central giant cell granuloma perforate cortical plates?
no, though will expand them
43
How does a central giant cell granuloma affect teeth?
displacement and resorption of roots
44
Are there hard tissues in central giant cell ganulomas?
osteoid or bone spicules may be present
45
How can you tell the difference between a central giant cell granuloma and hyperparathyroidism brown tumors?
based on serum calcium and phosphorous levels
46
Cherubism M?F
M>F
47
Preferred site of cherubism
mandible
48
How does puberty affect cherubism?
stabilizes condition
49
Cherubism histologically resembles what common lesions?
giant cell lesions
50
How does cherubism affect teeth?
interferes with development
51
Is radiation an acceptable therapy for cherubism?
No, it's contraindicated
52
Does cherubism have malignant potential?
No
53
How is cherubism treated?
It's self limiting | bone will usually remodel by the patient's early 20s
54
Fibrous dysplasia is associated with what syndrome? What are the clinical features associated with this syndrome?
Albrights syndrome involves several bones endocrine abnormalities
55
How does puberty affect fibrous dysplasia?
fibrous dysplasia becomes quiescent
56
Fibrous dysplasia maxilla?mandible
Maxilla>mandible
57
Fibrous dysplasia M?F
F>M
58
Fibrous dysplasia age predilection
late childhood | almost never begins in childhood but can persist into adulthood
59
Genetic mutation implication in fibrous dysplasia
gain of function in GNAS1 gene
60
Symptoms of fibrous dysplasia
slow onset of jaw asymmetry unilateral painless
61
How does fibrous dysplasia affect teeth?
teeth are normal but displaced
62
Radiographic features of fibrous dysplasia
ground glass or orange peel radiolucency | not well circumscribed
63
Pathologic features of fibrous dysplasia
proliferation of differentiated fibroblasts in swirling arrangement osteoid and calcified bone
64
Treatment of fibrous dysplasia
self limiting, usually burns out after puberty | may opt for cosmetic surgery but there's no need to remove the entire lesion
65
What is the risk of treating fibrous dysplasia with radiation?
malignant transformation

Oral Pathology (3 decks)

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