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Oral Pathology > Sample Questions > Flashcards

Sample Questions Flashcards

1
Q

Osteoma M?F

A

M>F

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2
Q

How can you differentiate between an osteoma and a torus?

A

Torus does not grow

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3
Q

What are the features of Gardner’s Syndrome?

A 
epidermoid/sebaceous cysts
fibromas
impacted and supernumerary teeth
osteomas
premalignant intestinal polyps
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4
Q

Do osteomas contain tooth structure?

A

can contain odontogenic remnants, tooth structures, and osteodentin

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5
Q

What is the origin of ossifying fibromas?

A

PDL cells

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6
Q

What is the most common location of ossifying fibromas?

A

mandible posterior to the canine

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7
Q

Ossifying fibroma M?F

A

F>M

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8
Q

Aggressive form of ossifying fibroma

A

juvenile active ossifying fibroma

can cause bone expansion

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9
Q

Symptoms of ossifying fibroma

A

asymptomatic

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10
Q

Radiographic features of ossifying fibroma

A

marble shaped

lytic lesion with radiopaque foci

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11
Q

Ossifying fibroma resembles what radiographically?

A

fibrous dysplasia

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12
Q

Osteoblastoma M?F

A

M>F

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13
Q

Symptoms of osteoblastoma

A

progressively growing painful lesion
may cause expansion of cortical plates
tender on palpation

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14
Q

Most common site of osteoblastoma

A

molar and premolar areas of the mandible

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15
Q

Pathologic features of osteoblastoma

A

vascular stroma
trabeculae of osteoid and immature bone
trabeculae rimmed with active proliferating fibroblasts

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16
Q

What is the main difference between an osteosarcoma and an osteoblastoma?

A

cartilage may be present in osteosarcoma, not in osteoblastoma
malignant osteoid present in osteosarcoma

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17
Q

Age predilection of osteosarcoma

A

10-25y

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18
Q

Most common site of osteosarcoma

A

mandible

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19
Q

Symptoms of osteosarcoma

A

mass, lump, or swelling

pain, paresthesia, nasal obstruction, nose bleeds

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20
Q

Describe the bone present in an osteosarcoma

A

immature, thin, not well mineralized

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21
Q

What are the 2 pathologic features necessary to characterize lesion as an osteosarcoma

A

malignant tumor osteoid and cytologically malignant cells

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22
Q

What are the most common metastasis sites for osteosarcoma?

A

lung and cervical lymph nodes

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23
Q

Does a chondrosarcoma contain tumor osteoid?

A

No, but does contain fully developed cartilaginous structures

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24
Q

What are the symptoms of chondrosarcoma?

A

expansion, loose teeth, nasal discharge

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25
Q

Chrondrosarcoma radiographic features

A

cotton wool calcifications
thick walled radiolucency
possibly widened PDL space

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26
Q

Which is more common in the jaws, a chondrosarcoma or a mesenchymal chondrosarcoma?

A

mesenchymal chondrosarcoma

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27
Q

Fibrosarcoma mandible?maxilla

A

mandible>maxilla

28
Q

Symptoms of fibrosarcoma

A

mass or swelling

pain, paresthesia, trismus

29
Q

Fibrosarcoma can clinically be confused for…

A

SCC

salivary gland tumor

30
Q

Fibrosarcoma affects teeth how?

A

can move teeth

root erosion

31
Q

Histologically, what bone tumor resembles a cross section of cable wire or fish swimming upstream?

A

fibrosarcoma

32
Q

What are 2 syndromes associated with Langerhans cell histiocytosis?

A

Hand-Schuller-Christian syndrome

Letere-Siwe syndrome

33
Q

In Langerhans cell histiocytosis, langerhans cells migrate from ? to ? to ?

A

from bone marrow to skin to lymph nodes

34
Q

Chronic focal LCH M?F and age?

A

M>F

children and young adults

35
Q

Chronic disseminated LCH characterized by

A

multifocal granulomas
skull lesions
exophthalmos
diabetes insipidus

36
Q

Acute disseminated LCH age predilection

A

infants

37
Q

Radiographic features of LCH

A

teeth float in air

skull lesions punched out

38
Q

LCH may mimic what in children (oral)?

A

juvenile periodontitis

39
Q

Age predilection of central giant cell granuloma

A

children and young adults

40
Q

Central giant cell granuloma M?F

A

F>M

41
Q

Most common location of central giant cell granuloma

A

anterior mandible

42
Q

Will a central giant cell granuloma perforate cortical plates?

A

no, though will expand them

43
Q

How does a central giant cell granuloma affect teeth?

A

displacement and resorption of roots

44
Q

Are there hard tissues in central giant cell ganulomas?

A

osteoid or bone spicules may be present

45
Q

How can you tell the difference between a central giant cell granuloma and hyperparathyroidism brown tumors?

A

based on serum calcium and phosphorous levels

46
Q

Cherubism M?F

A

M>F

47
Q

Preferred site of cherubism

A

mandible

48
Q

How does puberty affect cherubism?

A

stabilizes condition

49
Q

Cherubism histologically resembles what common lesions?

A

giant cell lesions

50
Q

How does cherubism affect teeth?

A

interferes with development

51
Q

Is radiation an acceptable therapy for cherubism?

A

No, it’s contraindicated

52
Q

Does cherubism have malignant potential?

A

No

53
Q

How is cherubism treated?

A

It’s self limiting

bone will usually remodel by the patient’s early 20s

54
Q

Fibrous dysplasia is associated with what syndrome? What are the clinical features associated with this syndrome?

A

Albrights syndrome
involves several bones
endocrine abnormalities

55
Q

How does puberty affect fibrous dysplasia?

A

fibrous dysplasia becomes quiescent

56
Q

Fibrous dysplasia maxilla?mandible

A

Maxilla>mandible

57
Q

Fibrous dysplasia M?F

A

F>M

58
Q

Fibrous dysplasia age predilection

A

late childhood

almost never begins in childhood but can persist into adulthood

59
Q

Genetic mutation implication in fibrous dysplasia

A

gain of function in GNAS1 gene

60
Q

Symptoms of fibrous dysplasia

A

slow onset of jaw asymmetry
unilateral
painless

61
Q

How does fibrous dysplasia affect teeth?

A

teeth are normal but displaced

62
Q

Radiographic features of fibrous dysplasia

A

ground glass or orange peel radiolucency

not well circumscribed

63
Q

Pathologic features of fibrous dysplasia

A

proliferation of differentiated fibroblasts in swirling arrangement
osteoid and calcified bone

64
Q

Treatment of fibrous dysplasia

A

self limiting, usually burns out after puberty

may opt for cosmetic surgery but there’s no need to remove the entire lesion

65
Q

What is the risk of treating fibrous dysplasia with radiation?

A

malignant transformation

Oral Pathology (3 decks)

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