Salicylate overdose Flashcards
1
Q
On overdose of what drug sis responsible for salicylate posioning?
A
Aspirin
2
Q
How can an overdose of aspirin present?
A
Nausea
Vomiting
Tinnitus
Headache
3
Q
What symptoms can present in a severe overdose of aspirin?
A
Hyperventilation
Secondary respiratory alkalosis develops
4
Q
What is the initial management of overdoses if they are recent?
A
Administer activated charcoal.
5
Q
What is the management of a minor overdose?
A
Supportive therapy
6
Q
What do significant overdoeses require?
A
Alkalinisation with IV sodium bicarbonate
7
Q
Why is IV sodium bicarbonate administered?
A
To maintain blood pH at 7.5-8.0
8
Q
What metabolic disturbance occurs in salicylate overdose?
A
Metabolic acidosis with a raised anion gap
