Safety & Techniques part I Flashcards
Name 2 CPB related problems ?
- Prevention
- Treatment
What type of protein is Protamine ?
Polycationic
What type of molecule is Heparin ?
Polyanionic
What is a major protamine reaction ?
3 Risk Factors ?
- Catastrophic pulmonary vasoconstriction.
- Vasectomized males
- Hx of PPHN
- Seafood allergies
What would be the Classification of the following Protamine Reaction:
Hypotension from rapid administration.
Type I
What would be the Classification of the following Protamine Reaction:
Anaphylactic reaction
Type II a
What would be the Classification of the following Protamine Reaction:
Immediate Anaphylactic reaction
Type II b
What would be the Classification of the following Protamine Reaction:
Delayed Anaphylactic reaction
Type II c
What would be the Classification of the following Protamine Reaction:
Catastrophic vasoconstriction
Type III
Preventions/ preparations for Protamine Reaction.
- Slow Injection
- Give peripherially
- Careful history
- LV fx
- Vasectomized pts.
- Redo’s
- Fish allergies
- Keep circuit intact
Treatment / Response to a Protamine Reaction.
- Administer Fluids
- Administer O2, Steroids, Epi
- Positive Pressure Ventilation
- Alpha vasopressor
- Dopamine
- If unresponsive:
- Give Heparin
- Reinstituted CPB
Prevention / Preparation for an AIR EMBOLISM
- Careful priming
- Flush CO2
- Level sensor
- Bubble sensor
- Arterial filter
- Pre-CPB checklist
- Verify before infusion
- Limit traffic
Treatment / response
for an AIR EMBOLISM
- Automatic pump shut down, if possible
- Protocol for massive air embolism during CPB
- Retrograde cerebral perfusion
Prevention / Preparation for Oxygenator Failure
- Preform Drills
- Diagnosis algorithm
- Check all gas connections
- To oxygenator
- vaporizer
- Correct source
- Kink free
- Size oxygenator to patient
- Check oxygenator for leaks
- Pre-CPB
Treatment / response
for an Oxygenator Failure.
- Assuming all optimizing steps have failed:
- Communicate
- Consider cooling
- Change-out membrane
- Pre-primed if poss.