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Respiratory pharmacology > SABA, LABA, LABA+ICS, LAMAs > Flashcards

SABA, LABA, LABA+ICS, LAMAs Flashcards

1
Q

Salbutamol/ Albuterol

A

Ventolin
SABA
Available as: MDI, DPI (diskus), nebule
Dosage: MDI -100mcg (qid) , DPI - 200mcg, SVN - 2.5mg/0.5ml
Onset: 15 minutes
Peak: 30-60 minutes
duration: 4-6 hours

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2
Q

Terbutaline

A

Bricanyl
SABA
Available as: turbuhaler
Dosage: MDI - 0.5mg qid
Onset: 15 minutes
Peak: 60-90 minutes
duration: 4-6 hours

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3
Q

Ipratropium Bromide

A

Atrovent
SAMA** not saba
Available as: MDI, nebule, nasal spray
Dosage: MDI -20mcg 2 inhs bid, SVN - 0.5mg qid
Onset: 15 minutes
Peak: 30-60 minutes
duration: 4-6 hours
COPD only

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4
Q

Ipratropium and salbutamol

A

Combivent Respimat
SABA and SAMA
Available as: respimat, nebule
Dosage: 20mcg ipratropium + 100mcg salbutamol
Dosage nebule: 0.5mg ipratropium + 2.5mg albuterol
**combination is more effective in COPD than either agent alone

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5
Q

Formoterol (1)

A

Foradil
LABA
Selective beta-2 antagonist
Available as: MDI
Dosage: 12mcg bid
Onset: 3 minutes
duration: up to 12 hours
Indication: Asthma and COPD

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6
Q

Formoterol (2)

A

Oxeze
LABA
Selective beta-2 antagonist
Available as: turbuhaler
Dosage: 6 or 12mcg bid
Onset: 3 minutes
duration: up to 12 hours
Indication: Asthma only

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7
Q

Salmeterol

A

Serevent
LABA
Available as: diskus
Dosage: 50mcg bid
Onset: 20 minutes
Peak: 3-5 hours
duration: 12 hours
Indication: Asthma and COPD

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8
Q

Glycopyrronium

A

Seebri
LAMA
Available as: breezehaler
Dosage: 50mcg once daily
Indication: COPD only

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9
Q

Aclidinium Bromide

A

Turdoza Genuair
LAMA
Potent agonist for all muscarinic receptors
Available as: MDI
Dosage: 400mcg bid

Indication: COPD only

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10
Q

Umeclidinium Bromide

A

Incruse Ellipta
LAMA
Available as: DPI
Dosage: 62.5mcg once daily
Indication:
Potent antagonist for all muscarinic receptors

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11
Q

Olodaterol

A

Striverdi
LABA
Available as: Soft Mist Inhaler (SMI)
Dosage: 2.5mcg once daily
duration: ultra long lasting - up to 24 hours
Indication: COPD maintenance

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12
Q

Formoterol + Mometasone

A

Zenhale
LABA + ICS
Available as: MDI
Dosage: 100 or 200mcg mometasone with 5mcg formoterol bid
Onset: 20 minutes
Peak: 3-5 hours
duration: 12 hours
Indication: Asthma only

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13
Q

Formoterol + Budesonide

A

Symbicort
LABA + ICS
Available as: DPI
Dosage: 100, 200 or 400mcg of budesonide + 6mcg or 12 mcg Formoterol
Onset: 3 minutes
duration: up to 12 hours
Indication: Asthma and COPD (more COPD)

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14
Q

Salmeterol & Fluticasone (1)

A

Advair OR Wixela
LABA + ICS
Available as: DPI
Dosage - COPD:
100, 250 or 500mcg Fluticasone with 50mcg salmeterol bid
Dosage - Asthma:
125 or 250mcg Fluticasone with 25mcg Salmeterol
Onset: 20 minutes
Peak: 3-5 hours
duration: 12 hours
Indication: Asthma and COPD

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15
Q

Vilanterol

A

LABA - not available as monotherapy, has to be given with an ICS
Indication: Asthma and COPD

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16
Q

Fluticasone & Vilanterol

A

Breo Ellipta
LABA + ICS
Dosage: 100mcg fluticasone + 25mcg vilanterol (asthma may have 200mcg steroid dose) once daily
Duration: ultra long lasting -24 hours
Indication: Asthma and COPD

17
Q

Fluticasone & Umeclidium & Velanterol

A

Trelegy Ellipta
LABA + LAMA + ICS
(umeclidium = anticholinergic)
Dosage: 100mcg fluticasone + 62.5mcg umeclidium + 25mcg vilanterol once daily
(Steroid dose higher in asthma)
Duration: ultra long lasting - 24 hours
Indication: Asthma and COPD

18
Q

Indacterol

A

LABA - not available as monotherapy, has to be given with ICS
Indication: asthma only
B2-selective agonist in fixed combinations

19
Q

Mometasone & Indacterol

A

Atectura
LABA + ICS
Available as: breezhaler
Dosage: 80, 160 or 320mcg mometasone + 150mcg indacterol
once daily
Duration: ultra long lasting, 24 hours
Indication: Asthma

20
Q

Mometasone & Glycopyrronium & Indacterol

A

Enerzair breezhaler
LABA + LAMA + ICS
Available as: breezhaler
Dosage: 160mcg mometasone + 50mcg glycopyrronium + 150mcg indacterol
duration: ultra long lasting, 24 hours
Indication: Asthma

21
Q

Tiotropium Bromide & Olodaterol

A

Inspiolto Respimat
LAMA + LABA
Available as: SMI
Dosage: 2.5mcg tiopropium + 2.5mcg olodaterol once daily
Indication:

22
Q

Umeclidinium Bromide & Vilanterol

A

Anoro Ellipta
LAMA + LABA
Available as DPI
Dosage: 62.5 mcg umeclidinium + 25mcg vilanteral once daily
Indication:

23
Q

Aclidinium Bromide & Formoterol

A

Duaklir Genuair
LAMA + LABA
Available as:
Dosage:
Duration:
Indication: Asthma

24
Q

Glycoppyrolate bromide & Indacterol

A

Ultibro breezhaler
LAMA + LABA
Available as: DPI
Dosage: 50mcg Glycoppyrolate bromide + 110mcg indacterol once daily
Duration: 24 hours
Indication: COPD

25
Q

Budesonide, Glycopyrronium Bromide & Formoterol

A

Breztri Aerosphere
ICS + LAMA + LABA
Available as: MDI
Dosage: 182mcg budesonide + 8.2mcg glycopyrronium + 5.8mcg formoterol BID
Duration: 12 hours
Indication: COPD

26
Q

Tiotropium bromide

A

Spiriva
LAMA
M1 & M3 selectivity
Available as DPI or respimat
Dosage:
DPI - 18mcg once daily
Respimat (SMI) - 2.5mcg once daily
Indication: MDI for COPD, respimat for Asthma

Respiratory pharmacology (1 decks)

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