SA Flashcards

1
Q

Define conscious sedation and general anaesthesia

A
  • reducing or stopping physiological responses without loss of consciousness, cooperation or protective reflexes. Used to ease discomfort/ stress/pain/anxiety
    -depresses the CNS
    -verbal contact remains

-GA= absence of sensation, without the ability to maintain physiology function such as breathing and protective reflexes. Carried out in hospital setting

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2
Q

What drugs is used for conscious IV sedation and its dose. What is its reverse drug

A

-midazolam 5mg/5ml (3mg total usually over 3 mins)
0.5mg - sedated, 25g anaesthetised
-flumazenil - 200ug initially, 100ug/min, 1mg max (only used in emergencies, not speeding up recovery)

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3
Q

Indications/ Types of patients that benefit from sedation

A

*Moderate dental anxiety/ phobias
*Children - Used more routinely as part of behavioural management (eg. if uncooperative)
*Medically compromised patients - Stress precipitates conditions e.g. asthma, angina, hypertension
*Special needs patients -poor cooperation with mild learning disability, cerebral palsy, Parkinson’s etc.
*Poor Gag and swallow reflex
*Persistent fainting
*Traumatic dental procedures (MOS, implants)

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4
Q

Contraindications for IV sedation

A

-Allergy
-Unwilling/uncooperative
-Unaccompanied- no escort available
-Very old - liver and kidney affects metabolism
-Children<12 -Sensitive to dosage with young people. Restless in chair (opt for GA as safer)
-Severe psychiatric disease
-Severe or uncontrolled systemic disease- e.g. recent MI, COPD
-Hepatic or renal insufficiency -Won’t metabolise the drug
-Pregnancy and breastfeeding
-severe needle phobia
-poor veins
-methotrexate?
-high BMI (if >36) or sleep apnoea- done in hospital)
-responsibilities- caring for children
-recent alcohol or rec drugs

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5
Q

Contraindications for RA sedation

A

-poor nasal airway- heavy cold, deviated septum
-Claustrophobic patients
-Middle Ear/Sinus Infection (nitrous oxide can go into air filled cavities and increase pressure in these areas)
-Certain types of occular surgery
-Behavioural problems/Personality disorders, poor cooperation
-URTI
-Severe anxiety
-1st trimester of pregnancy (if essential then do 2nd trimester and 30% max)
-Methotrexate?
-Bleomycin therapy
-COPD

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6
Q

What affect does methotrexate have with nitrous oxide

A

The drug Causes depletion of folate. With nitrous oxide can cause dangerous low levels of folate

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7
Q

Why bleomycin sulphate is contraindicated with nitrous oxide

A
  • anti-neoplastic therapy
  • due to the increased incidence of pulmonary fibrosis and other lung diseases.
  • predisposed to respiratory failure following exposure to high concentrations of oxygen over 25%.
    -Since use of 100% oxygen is part of the standard sedation procedure (in both the initial and recovery phases) there is an increased risk of possible problems in these patients.
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8
Q

Where does metabolism and excretion of IV and inhalation drugs occur

A

-IV: liver metabolism, kidney excretion
-RA: small metabolism in liver. Excretion in lungs

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9
Q

Types of drugs that increase risk of respiratory depression and drop in BP with midazolam

A

-Antihypertensives= HUGE DROP IN BP
-ritonavir (antiviral) = extreme risk of respiratory depression

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10
Q

What is included in patient assessment before sedation (RA and IV) Instructions given to pt

A

-suitability (why it is needed)
-record baseline HR, BP, respiratory rate, BMI, oxygen saturation
-give instructions. Discuss risks
- MH
-gain written consent
-check understanding of procedure
-explain they need an escort home (only for IV), light meal before hand, no alcohol or rec drugs prior (synergistic effect)
-ask if had previous sedation (can help indicate how much to give)

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11
Q

What is the ASA classification system

A

-American Society of Anaesthesiologists
-Classification based on physical status
-Allocation of patients to grades according to:
o Medical status
o Operative/anaesthetic risk
-Estimation of fitness for sedation or GA
- I to V

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12
Q

What is ASA I. What is their BP

A

-patient without systemic disease; a normally healthy patient
-minimal anxiety
<60 years old
< 140 / 90 BP

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13
Q

What is ASA II

A

-MILD systemic disease - well-controlled (asthma, non-insulin diabetes, anaemia)
-very phobic, overweight (BMI 30-40), pregnant, special needs, drug allergy, smoker, alcoholic
-OR any healthy patient >60 years old (slower physiology)
< 160 / 95 BP

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14
Q

What conditions fit in the classification of ASA III.

A

-MODERATE systemic disease; which limits function but is not incapacitating
-poorly controlled insulin diabetes, epilepsy, angina, COPD, asthma etc
-Chronic bronchitis or emphysema
-Congestive heart failure or thyroid disease
< 200 / 115 BP
BMI>40

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15
Q

What is ASA IV

A

INCAPACITATING SYSTEMIC DISEASE; which is a constant threat of life
- sepsis, ongoing cardiac ischemia
-<3 months Post MI or CVA or TIA or stent
-COAD or CHF requiring O2 therapy
-Uncontrolled dysrhythmias
-Blood pressure > 200 / 115

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16
Q

What is ASA V and VI

A

5=moribund patient not expected to survive 24 hours unless treated
6= brain dead

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17
Q

Why someone with insulin dependant diabetes (type I) is at risk during sedation

A

-likely will go hypo as cannot eat the morning of sedation however will still take insulin = glucose stores will be depleted rapidly and pt becomes hypo – difficult to tell this is happening when sedated

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18
Q

Which ASA classifications (I-V) are suitable for sedation in a GDP

A

*ASA I = Suitable for sedation in GDP
*ASA II= Suitable for sedation in GDP; with appropriate precautions
*ASA III= Increased risk > usually refer to hospital
*ASA IV / V = Life-threatening disease = must be treated in hospital (should be by an anaeshtetist)

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19
Q

Indications for cannulation in dentistry

A

1.IV drug administration
-Prophylaxis (antibiotic/steroid cover)
-Medical Emergency
2. IV sedation

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20
Q

Sites for cannulation. Pros and cons for each

A
  1. Dorsal veins of the hand
    -Easily visible, superficial veins. No vital structures
  2. Antecubital fossa (basilic, cephalic, median cubital veins)
    -Large veins
    -Danger of brachial artery & median nerve
    -Problems with joint movement
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21
Q

Step by step technique of cannulation

A

-Draw up 0.9% saline into 5ml syringe
-Select 22g venous cannulae & check its working order
-Select an appropriate vein.
-Apply tourniquet, 10cm above cannulation site
-Wait for vein to become engorged (hand clenching, tapping vein)
-Alcohol Wipe surface
-Tense skin & insert cannula at an angle of 10-15 degrees through skin and into the vein
-A 1st flash-back of blood at white cap end indicates the cannula has entered the vein
-Withdraw the metal needle slightly (0.5cm) so can see needle end and flashback
-Advance cannula up to its hub
-Remove tourniquet
-Remove metal insertion needle & place end cap – be quick
-Secure cannula with tape & administer 2-5ml 0.9% saline into injection port (if lump appears then cannula is subcutaneous > so remove & resite)
-5mg in 5ml drawn into 5ml syringe. Injected 1mg every 1 minute

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22
Q

Complications that can arise during cannulation and how to overcome

A

1.Difficult Veins
=Be patient
2.Extra-venous Cannulation
-Pain on cannulation
-Formation of subcutaneous lump
=Resite cannula
3.Intra-arterial Injection
-Significant pain, bright red pulsatile blood
=remove needle, apply pressure (+/- refer)
4.Haematoma Formation
-Avoid multiple venepuncture
-Avoid penetrating opposite wall of vein
=apply Pressure after cannula removed
5. Pain in arm, fingers, back of hand

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23
Q

IV sedation procedure

A

-Cannulation
-Record arterial oxygen saturation (>97%) Respiratory rate, HR, BP every 5 mins
-Draw up midazolam 5mg/5ml in 5 ml syringe
-1mg injected slowly. Wait 1 minute. Then 1mg every minute thereafter
-Slow titration against to patient effect
-Flush with saline to make sure all in system
-Commence dental treatment

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24
Q

Why administer midazolam in increments

A

1mg over 1 minute (sometimes 0.5 mg if history of fast effect)
So you can monitor the patient while it takes effect as it take 40 seconds to get to brain

25
Q

Signs of sedation

A

-Slurring and slowing of speech
-Relaxed appearance
-Delayed response to commands
-Ptosis – drooping of upper eyelids
-Willingness to undergo treatment
-Feeling warm and tingly

26
Q

Things to check before discharging patient after IV sedation

A

-Monitor arterial oxygen saturation for at least 1 hour after last increment (>97%)
-Discharge: at least 1 hour after last increment, with escort, can walk in straight line, satisfactory BP and oxygen saturation
-written and verbal POIG: no drinking, driving, signing legal docs, operating machinery for 24 hrs

27
Q

Complications of IV sedation

A

-Respiratory depression: due to reduced arterial oxygen saturation
-Over-sedation
-Disinhibition – react in complete opposite way to expected= Uncooperative/ aggressive/ violent
-Medical emergencies (epilepsy seizure won’t occur)
-Allergy to midazolam

28
Q

What to do if oxygen saturation drops during sedation

A

=over sedation, respiratory depression. Signs=nausea, headache, vomitting, loss of consciousness
-Get patient to take deep breaths, tilt chin back and opening airway.
-If <94%: Supplement oxygen can be given - 3l/min
-If <90% then use faster flow of oxygen in mask
-Or if this does not work use flumazenil (reversal)

29
Q

Can you use sedation if pregnant or breastfeeding

A

If pregnant:
-No IV: can affect the baby
-No RA as can affect baby. If essential then in 2nd trimester as in 1st it can cause developmental issues and 3rd it can cause preterm birth

If breastfeeding:
-RA fine as out of system immediately
-Avoid IV, but can do if for 24 hours using formula or use pumped milk

-can’t be is same room as someone getting RA

30
Q

Differential diagnosis of loss of consciousness

A

-Vasovagal attack (faint)
-Over-sedation
-Cardiac arrest – no pulse/ not breathing
-Hypo-glycaemia – if pt has insulin but no breakfast – MH IMPORTANT
-Adrenal crisis
-Cerebrovascular Accident - stroke
-Epileptic seizure

31
Q

Signs and symptoms of vasovagal syncope

A

=Vasodilation in vessels going toward skeletal muscles – BP drops. Not enough Cardiac output to maintain blood to brain
-Cause - anxiety, pain, fatigue, fasting

Signs and symptoms:
-Nausea, pallor
-Sweating
-Pulse - weak/thready. rapid (conscious) then sudden slow (unconscious)
-Sudden loss of consciousness
-Fits & cyanosis

32
Q

Management of vasovagal syncope

A

-Supine + raise legs (ALLOWS BLOOD TO RUSH BACK TO BRAIN)
-Glucose drink & reassurance
-Oxygen (10 litres per min)
-Monitor breathing & pulse
-If recovery not rapid (within 1-2 mins), re-consider diagnosis

33
Q

Signs and symptoms of hypoglycaemia

A

-Cause: poorly controlled diabetes, Missed meal but has insulin, Infection, Fever

Warning (adrenergic signs):
-Irritable/uncooperative = less compliant with dental treatment
-Hunger, dry mouth
-tremor
-palpitations, sweating

Established signs:
-Drowsiness/ disorientation
-confusion
-aggression
-slurred speech
-Gradual loss of consciousness

34
Q

Management of hypoglycaemia

A

-Confirm glucose level (< 4 mmol/l)
-If Conscious = glucose/dextrose drink or tablets/gel
-If Unconscious = glucagon 1mg IM. Takes 10-15 mins to work + oral glucose once conscious
-Oxygen & monitor (glu >5mmol/l)
-Paramedics to check pt afterwards – pt will feel very sleepy afterwards

35
Q

Differential diagnosis of acute chest pain. And breathing problems

A

-Stable angina
-Acute coronary syndromes (unstable angina and MI) – persists with GTN
-GORD
-Pleuritic pain
-Pulmonary embolism
-Musculoskeletal
-Panic attack

-Asthma attack
-Anaphylaxis

36
Q

Causes of stable angina, signs and symptoms

A

-Reversible Myocardial ischemia -coronary artery blocked with atheroma, not enough O2 gets through when heart is stressed

Signs:
-Severe retrosternal pain (behind sternum) on exercising or stress
-May radiate down left arm and jaw
-Regular pulse

37
Q

Management of stable angina attack

A

-Glyceryl trinitrate (GTN) spray (400ug) – this treats it, unlike MI
-Sublingual – if swallowed, will go to liver and 90% will be broken down ASAP
-Repeat every 5 mins, up to 3 times
-Oxygen (10 litres per min)
-Monitor = if no relief, consider possibility of MI

38
Q

Signs and symptoms of acute coronary syndromes (unstable angina and MI)

A

*Causes
-Fissure of atheromatous plaque=Coronary occlusion
=Sudden ischaemia =Irreversible damage to heart muscle

*Signs
-Crushing retrosternal pain at rest
-Death-like appearance
-Breathless, vomiting, distress
-Weak, irregular pulse, loss of consciousness, potential cardiac arrest

39
Q

Management of unstable angina or MI

A

-Comfortable position
-Oxygen
-Call paramedics
-GTN Spray
-Nitrous oxide 50% with oxygen 50% (if available) – same analgesic effect as MORPHINE & it causes vasodilation
-Aspirin 300mg orally
-Monitor for cardiac arrest

40
Q

Signs and symptoms of asthma. Exacerbating factors

A

Exacerbated by anxiety, Stress, Exercise, Infection, Allergy, cold air, pollen
-Breathlessness
-Cannot form sentences
-High RR>25
-Wheezing on expiration/ cough
-Tachycardia >110
-Accessory muscles of respiration

Worrying sings= bradycardia, cyanosis, low RR, confusion, exhaustion, decreased level of concsiousness

41
Q

Management of asthma

A

-Sit upright
-2 puffs Salbutamol inhaler +/- spacer (100ug/puff) every 10 mins up to 10 puffs
-Oxygen (10 litres per min)
-Call paramedics (if no improvement or status asthmaticus)

42
Q

Cause of anaphylaxis. What type of hypersensitivity is it

A

-Immediate type I hypersensitivity reaction
-Exposure to antigen in a sensitised individual

-Antigen > attaches to IgE antibody on eosinophils & mast cells > degranulation & release of mediators
=Bronchospasm, vasodilatation, oedema, hypotension

43
Q

Signs and symptoms of anaphylaxis

A

-Facial flushing (vasodilation)
-Oedema
-Acute breathlessness (bronchospasm)
-Weak/ impalpable pulse (Severe hypotension)
-Loss of consciousness
-rash that blanches

44
Q

Management of anaphylaxis

A

-Supine and raise legs
-Adrenaline 1:1000 0.5ml (0.5mg) IM – NEVER IV
-If required repeat after 5 mins
-Oxygen
-Call paramedics

45
Q

List guidelines for conscious sedation

A

IACSD 2015
SDCEP 2017

46
Q

Indications for GA in dentistry

A

Routine extractions:
* Where LA/sedation has failed
* Acute infection
* Multiple primary extraction in very young patients
* (usually Not for orthodontic extractions)

Complex extractions – surgical extractions, full clearance
Routine dental treatment in special cases -Severe learning difficulties or movement issues

47
Q

Safety features incorporated into the inhalation sedation equipment

A

-colour coding (NO is blue, Oxygen is white)
-oxygen fail safe - nitrous oxide automatically cut off if oxygen run out
- oxygen flush- if pt feeling over sedated
-reservoir bag- Ensures patient is breathing correctly – easy to visualize
-minimum oxygen percentage of 30%
-Air entrainment valve: If gases run out the valve will open and allow patient to breath air
-gas pressure dials
-active scavenging system - vacuum to limit gas released into atmosphere
-one way valve
-emergency cut off

48
Q

How often is RA equipment serviced

A

6 monthly/yearly service
Daily checks before use- check bag inflates, correct flow rate, tubes connected properly

49
Q

Explain inhalation sedation

A

-A semi-hypnotic technique of conscious sedation in which nitrous oxide and oxygen produce physiological changes to alleviate anxiety so that the patient can co-operate sufficiently to allow dental treatment to take place
-The patient should remain conscious and co-operative through out with all vital reflexes intact. Should be able to communicate throughout

50
Q

Advantages of inhalation sedation over IV

A

-Rapid absorption and onset: 2-3 minutes for clinical signs
-Rapid peak action: 3-5 minutes
-Depth of sedation easily regulated
-Duration of sedation flexible
-Rapid elimination and recovery: 3-5 minutes on 100% oxygen
-Moderate analgesia effect
-Non-invasive-No injection
-Few side effects
-Drug not metabolised
-No adverse effects on the liver, kidneys, brain, cardiovascular system or respiratory systems
-Don’t need an escort (unless child)
-children react more predictably than IV so best option

51
Q

Disadvantages of RA

A

-Cost of equipment
-Space occupying equipment
-Not a potent agent
-A degree of co-operation is necessary- breathing through nose
-Possibility of chronic exposure
-drug must be administered continuously
-mask may get in way of treatment

52
Q

Pre-op instructions for RA

A

-A light meal 2 to 4 hours before appointment
-Children must be accompanied by a responsible adult and be supervised for rest of day
-Adults don’t need escort
-Transport home in car or taxi
-Children should not ride bikes, drive vehicles or operate machinery for the rest of the day
-If have a cold, ask if can breath through nose fine
-Pregnant mums or other children not allowed in room

53
Q

Step by step technique of RA administration

A

-Set dial to 100% oxygen
-Settle patient in the chair
-Turn on oxygen at a rate of 4-6L/min
-Ask patient to place nasal hood on nose, ensuring good seal and breathing through nose
-Continual reassurance: explain they are in warm sunny place with tingly hands and feet
-Turn dial to 90% oxygen, 10% nitrous oxide
-After 1 minute turn dial to 80% oxygen
-Continue 5-10% increments every minute until suitable level of sedation
-20%-50% nitrous oxide commonly allows good sedation
-If bag over inflated – reduce flow rate and vise versa
-Commence treatment
-When treatment complete switch to 100% oxygen
-Breath for 2- 3 minutes (to prevent Diffusion Hypoxia)
-Remove nasal hood & sit patient up, check not dizzy
-Discharge home with post-op instructions

54
Q

Causes of failure of RA technique

A

Nasal obstruction
Patient mouth breathing
Inefficient seal of nasal hood
Extreme anxiety
Fault in machine

55
Q

Management of RA over-sedation

A

Oxygen flush
Reduce nitrous oxide by 5 to 10%
Reassure patient
Monitor patient
Continue or postpone treatment

56
Q

Options if patient has large needle phobia and is very anxious

A

Ask what in particular about needles they don’t like- the sight, the feel etc and can work around it
-RA + IV
-nasal sedation + IV
-Oral pre-med (temazapam 10mg tablet or solution)
-Surface anaesthesia 1hr pre
-GA

57
Q

Action of benzodiazepine

A

-act on neuronal membrane within the brain and spinal cord
-act on GABA receptors which are inhibitory. More permeable to chloride ions and increase firing. Prolongs time it takes for re-polarisation. During this refractory period no further electrical stimuli can be transmitted across the synapse
-sensory messages are reduced
-produces pharmacological sedation, anxiolysis,
amnesia, muscle relaxation and anticonvulsant effects. Minimal cardiovascular depression
-flumazenil is an antagonist as has greater affinity for the benzodiazepine receptor than the active drugs and therefore displaces
them.

58
Q

What is the half life of midazolam

A

1-2 hours