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Digestive system disorders > S4 MTB - Colon cancer > Flashcards

S4 MTB - Colon cancer Flashcards

1
Q

What type of tumor does this cancer lead to

A

Adenocarcinoma

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2
Q

Principal gene involved in colon cancer

A

APC “APColon”

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3
Q

How does this cancer start?

A

All colon cancer starts with the presence of a polyp

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4
Q

Types of polyps (adenomas)

A
  • Tubular
  • Tubulovillus
  • Villous
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5
Q

Percentage of malignancy in regards to the types of polyps

A
  • 2.8% tubular
  • 8.4% tubulovillus
  • 9.5% villus
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6
Q

Polypus syndromes can be divided into 2 principal syndromes

A
  • Adenomatous
  • Hamartomatous
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7
Q
  • Familial Adenomatous Polypus
  • Gardner Syndrome
  • Turcot Syndrome
    These 3 are part of what subdivision of polypus syndromes
A

Adenomatous

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8
Q

-

A

Hamartomatous

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9
Q

Screening for colorectal cancer is done at what age?

A

Some literatures say at 50 years but recently it has been determined that by the age of 45 years

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10
Q

How is colorectal cancer screening done?

A
  • FIT: fecal immunochemical test
  • Colonoscopy can detect polyps; can get them removed there
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11
Q

Classic sign in cancer screening

A

Apple-bite sign

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12
Q

Symptoms of colon cancer

A

Patients are asymptomatic until it gets bad
- Anemia
- Bleeding
- “Heces acintadas”

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13
Q

TNM for colon cancer

A
  • T1: only at mucosa + submucosa
  • T2: at muscle
  • T3: at serosa
  • T4: ALL OF IT
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14
Q

Most common place for a colorectal cancer to do metastasis

A

Liver

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15
Q

Cure for colorectal cancer

A

SURGERY

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16
Q

How will the surgery be done

A

Depending on the location, taking all lymphatic nodules and irrigation with it.
Taking most of the colon, not partial:(

17
Q

Chemiotherapy for colorectal cancer

A
  • 5-FU/ LV/ mFOLFOX6
  • bolus of: 5-FU/LV/oxaliplatin (FLOX)
  • CapeOx (capecitabine/oxaliplatin)
18
Q

Screening for someone with a family relative that has FAP

A

10 to 15 years

19
Q

Treatment for FAP

A

Total colectomy between the age of 18 to 20 years

20
Q

Gene that’s mutated in Peutz-Jegers syndrome

A

SK11

21
Q

Criteria for diagnosing Lynch Syndrome

A

Amsterdam II criteria

22
Q
A

Digestive system disorders (8 decks)

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