S4) Blood Supply to the Brain Flashcards

1
Q

There are two paired arteries which are responsible for the blood supply to the brain.

What are they?

A
  • Vertebral arteries
  • Internal carotid arteries
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2
Q

What is the Circle of Willis?

A
  • The Circle of Willis is the anastomotic circle formed from the terminal branches of the ICA and vertebral arterie
  • From this circle, branches arise which supply the majority of the cerebrum
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3
Q

Describe the anatomical course of the internal carotid artery

A

⇒ Originates at the bifurcation of the common carotid artery (C4)

⇒ Move superiorly within the carotid sheath

⇒ Enter the brain via the carotid canal of the temporal bone

⇒ Pass anteriorly through the cavernous sinus

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4
Q

Distal to the cavernous sinus, the internal carotid artery gives rise to four branches.

Identify these branches as well as the respective region they supply

A
  • Ophthalmic artery – supplies structures of the orbit
  • Posterior communicating artery – acts as an anastamotic connecting vessel in the CoW
  • Anterior cerebral artery – supplies part of the cerebrum
  • Middle cerebral artery – supplies the lateral portions of the cerebrum
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5
Q

Describe the anatomical course of the vertebral arteries

A

⇒ Originates from the subclavian artery (medial to anterior scalene muscle)

⇒ Ascends up the posterior side of the neck, through the foramen transversarium

⇒ Enters the cranial cavity via the foramen magnum

⇒ Gives off branches, then converge to form the basilar artery

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6
Q

Within the cranial vault, the vertebral artery gives rise to three branches.

Identify these branches as well as the respective region they supply

A
  • Meningeal branch – supplies the falx cerebelli
  • Anterior and posterior spinal arteries – supplies the spinal cord, spanning its entire length
  • Posterior inferior cerebellar artery – supplies the cerebellum
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7
Q

There are three main paired constituents of the Circle of Willis.

Identify them as well as their origins

A
  • Anterior cerebral arteries – terminal branches of the internal carotid arteries
  • Internal carotid arteries – immediately proximal to the origin of the middle cerebral arteries
  • Posterior cerebral arteries – terminal branches of the vertebral arteries
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8
Q

To complete the circle, there are two connecting vessels present.

Identify these as well as their role

A
  • Anterior communicating artery: connects the two anterior cerebral arteries
  • Posterior communicating artery: connects the ICA to the posterior cerebral artery
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9
Q

There are three cerebral arteries.

Identify them as well as the respective portion of the cerebrum that they supply

A
  • Anterior cerebral arteries – supply the anteromedial portion of the cerebrum
  • Middle cerebral arteries – supply the majority of the lateral part of the brain
  • Posterior cerebral arteries – supply both the medial and lateral parts of the posterior cerebrum
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10
Q

The spinal cord is primarily supplied by three longitudinal arteries, as it descends from the brainstem to the conus medullaris.

Identify them as well as their origins

A
  • Anterior spinal artery – formed from branches of the vertebral arteries and travel in the anterior median fissure, terminating as sulcal arteries
  • Two posterior spinal arteries – originate from the vertebral artery / the posteroinferior cerebellar artery, anastomosing in the pia mater
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11
Q

Below the cervical level, longitudinal arteries offer insufficient blood supply. There is support via anastomosis with the segmental medullary and radicular arteries.

Describe the location of the segmental medullary arteries

A

Anterior and posterior segmental medullary arteries originate from spinal branches of many of arteries, then enter the vertebrae through the intervertebral foramina

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12
Q

Below the cervical level, longitudinal arteries offer insufficient blood supply. There is support via anastomosis with the segmental medullary and radicular arteries.

Describe the regions supplied by the radicular arteries

A
  • The radicular arteries supply the anterior and posterior nerve roots
  • Some radicular arteries may also contribute to supplying the spinal cord
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13
Q

What is the great anterior segmental artery of Adamkiewicz?

A

The great anterior segmental artery of Adamkiewicz reinforces circulation to the inferior 2/3 of the spinal cord, and is found on the left in the majority of individuals

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14
Q

What is a stroke?

A

A stroke is an acute development of a neurological deficit, due to a disturbance in the blood supply of the brain

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15
Q

There are four main causes of a cerebrovascular accident.

Identify and describe them

A
  • Thrombosis – obstruction of a blood vessel by a locally forming clot
  • Embolism – obstruction of a blood vessel by an emboli formed elsewhere
  • Hypoperfusion – lack of blood supply to the brain, due to systemically low blood pressure e.g shock
  • Haemorrhage – an accumulation of blood within the cranial cavity
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16
Q

What is the most common cause of a cerebrovascular incident?

A

Embolism – in many patients, an atherosclerotic emboli will arise from the vessels of the neck

17
Q

What is an aneurysm?

A
  • An aneurysm is a dilation of an artery, which is greater than 50% of the normal diameter
  • They are most likely to occur to occur in the vessels contributing to the Circle of Willis
18
Q

What is a spinal cord infarction?

A
  • A spinal cord infarction (aka spinal stroke) refers to the death of nervous tissue, which results from an interruption of the arterial supply
  • Clinical signs include muscle weakness, paralysis and loss of reflexes
19
Q

What are the most common causes of spinal infarction?

A
  • Vertebral fractures/dislocations
  • Vasculitic disease
  • Atheromatous disease
  • External compression e.g. abdominal tumours
20
Q

What are the lenticulostriate arteries?

A

The lenticulostriate arteries are small, deep penetrating arteries which branch from the middle cerebral artery