S1_L1-2: Approach to Diagnosis & Neuro Exam Flashcards
Signs/Symptoms of increased intracranial pressure (IICP) in NON-INFANTS
Headache, vomiting, papilledema, lateral rectus palsy (diplopia with internal squint), altered sensorium (deterioration in the level of consciousness), and Cushings Triad (↑ BP, ↓ Pulse, ↓ Respirations)
Signs/Symptoms of meningeal irritation
Headache, nuchal (neck) rigidity, Brudzinski’s Sign, Kernig’s Sign
Signs/Symptoms of increased intracranial pressure (IICP) in INFANTS
Bulging fontanel, separation of sutures, and rapid enlarging head size (Hydrocephalus)
What is the Normal Respiratory Rate (Breaths per minute)?
12-20 breaths per minute
Explain how to perform the Brudzinski’s Sign.
Patient is in supine and the examiner flexes the patient’s neck.
What is the expected findings in a (+) Brudzinski’s Sign?
Patient will involuntarily flex hip and knee. (+) wincing pain
Explain how to perform the Kernig’s Sign.
Patient is supine and the examiner flexes the patient’s hip, then extends the knee.
What is the expected findings in (+) Kernig’s Sign?
Patient feels an excruciating pain.
What is a secondary tumor of the brain?
A tumor that grows outside the CNS
What is a primary tumor of the brain?
A tumor that grows within the CNS
Type/Distribution of MASS LESION
Focal
Type/Distribution of PERIPHERAL NEUROPATHY
Diffuse
Type/Distribution of MULTIPLE SCLEROSIS
Multi-focal
Type/Distribution of NUTRITIONAL ENCEPHALOPATHY
Diffuse
A neurologic illness with a bulbar onset manifests with?
Swallowing and speech problems
Diagnostic test that is MORE SENSITIVE to mass lesions, strokes, brain abscess, and demyelinating disease COMPARED TO A CT SCAN?
Magnetic Resonance Imaging (MRI)
It is a cortical electrodiagnostic study
Electroencephalogram (EEG)
It is used to detect myopathies
Muscle Biopsy
Ancillary procedure for hypokalemic paralysis
Serum Potassium
The GOLD STANDARD of Angiograms
Digital Subtraction Angiogram / Catheter Angiogram
Angiogram that is NON-INVASIVE?
Magnetic Resonance Angiogram
Angiogram that is the MOST ACCURATE BUT INVASIVE?
Catheter Angiogram / Digital Subtraction Angiogram
Diagnostic test used to detect TB of the spine?
Spine X-ray
Medical term for TB of the spine?
Pott’s Disease
What is the Transcranial Doppler Ultrasound (Ultrasonography) used for?
Stroke, Hydrocephalus
What is the purpose of the ancillary procedure: Serologic Test
It is used to identify the different types of bacteria or virus causing the infection
Diagnostic test for Myoneural Junction (Neuromuscular Junction) Disorders?
Nerve Stimulation Studies (NSS)
Components of the Cushings Triad?
↑ BP, ↓ Pulse (Bradycardia), and ↓ Respirations
What are the prominent bladder signs?
Bowel or bladder incontinence, constipation, dysuria, and no bowel movement.
A lesion that is bilateral and often presents with a symmetrical deficit is in the level of the _____?
Spinal cord
TRUE OR FALSE: The cerebrum is responsible for fine movements.
False
TRUE OR FALSE: Cerebellar affectation presents with incoordinated movements. It does not present with weakness.
Both statements are true.
Cause of Amyotrophic Lateral Sclerosis (ALS)
Degenerative
Cause of Alzheimer’s Disease, Dementias
Degenerative
Cause of Myasthenia Gravis
Immunologic, autoimmune
Cause of Spina Bifida
Congenital / Developmental
Cause of subarachnoid hemorrhage
Trauma / neurotrauma
Cause of Hyponatremia
Toxic / metabolic
Cause of brain abscess
Infection
Cause of Stroke
Vascular / Circulatory problem
Source: Merritt’s Neurology, 14th ed.
Due to cerebral ischemia or hemorrhage. It strikes “out of the blue” and manifests as hemiparesis or other focal brain signs
Cause of Arteriovenous Malformation (AVM)
Congenital / Developmental
Cause of B1, B6, B12 Defiency
Nutritional
What is the most common vascular / circulatory problem?
Stroke
Cause of Parkinson’s Disease
Degenerative
Cause of Landry-Guillain-Barre Syndrome
Demyelinating and autoimmune
Cause of meningitis
Infection
Cause of intracerebral hemorrhage
Trauma / neurotrauma
Cause of aneurysm
Congenital / Developmental
TRUE OR FALSE: In a spinal cord lesion, there are normal findings above the level of the lesion.
True
TRUE OR FALSE: Atrophy occurs with time in a peripheral nerve lesion.
True
Other name for Bilateral Pyramidal Tract Signs
Pathologic Reflexes
Cause of Craniostenosis
Congenital / Developmental
Cause of hypercalcemia
Toxic / metabolic
Cause of Encephalitis
Infection
What is a tumor?
A tumor is an abnormal enlargement or proliferation of cells.
Cause of Multiple Sclerosis
Demyelinating and immune
Cause of epidural and subdural hematomas
Trauma / neurotrauma
Onset of trauma
Acute
Onset of degenerative disease (slowly progressive)
Chronic
Onset of intoxication
Alcohol, exposure to poison or chemicals
Subacute
Onset of mass lesions
Chronic
Onset of infections
Subacute
Onset of vascular diseases
Acute
Onset of nutritional disorder/lesion
E.g. lack of thiamine, lack of pyridoxine
Subacute
Onset of metabolic diseases
Subacute
Onset of acute demyelinating disease
Acute
Type/Distribution of VASCULAR DISEASE
Focal
Type/Distribution of Metastasis
Multiple Tumors
Multi-focal
Type/Distribution of Metabolic Encephalopathy
Diffuse
What does a focal type/distribution of lesion mean?
The lesion is restricted to one area
What does a multi-focal type/distribution of lesion mean?
Lesion is present in multiple areas
Type/Distribution of a demyelinating disease
Multi-focal
Type/Distribution of Toxic Encephalopathy
Diffuse
Diagnostic Test for Fractures
Skull X-Ray
Diagnostic Test for Guillain-Barre’s Syndrome
Nerve Stimulation Studies (NSS)
Diagnostic Test for Seizures
Electroencephalogram (EEG)
Diagnostic Test for Aneurysm
Angiogram
Diagnostic Test for Dermatomyositis
Total Creatine Phosphokinase (CPK)
Diagnostic Test for Subarachnoid Hemorrhage
Lumbar Puncture
Diagnostic Test for Myasthenia Gravis
Nerve Stimulation Studies (NSS)
Diagnostic Test for Arteriovenous Malformation (AVM)
Angiogram
Diagnostic Test for Polymyositis
Total Creatine Phosphokinase (CPK)
Diagnostic Test for Neuropathies
Nerve Stimulation Studies (NSS)
In performing Babinski sign, we use the (1) end of the key to strike the (2) aspect of the end of the foot going (3) towards the (4).
- Pointed
- Lateral
- Upwards
- Big toe/Great toe
Normal Response of Babinski Sign is —–. Abnormal Response of Babinski Sign is —–.
Normal: Plantarflexion (flexion) of all toes
Abnormal: Extension of big toe and flexion / fanning of small toes
TRUE OR FALSE: Babinski sign is present during the first year of life.
True. Reason: The corticospinal tract is not myelinated until the end of the first year of life. (Source: Snell)
A +++ grade in DTR / MSR indicates:
Increased reflex
Which segments are tested in the Brachioradialis reflex?
C5-C6
TRUE OR FALSE: Deep tendon reflex is more accurate than muscle stretch reflex.
False.
TRUE OR FALSE: In DTR, reflex muscle contraction mediated by the upper motor reflex arc.
False. It is mediated by the lower motor reflex arc.
Hyperreflexia is caused by a (1), while hyporeflexia is caused by a (2).
- Upper motor neuron lesion
- Lower motor neuron lesion
Cause of cerebral contusion / concussion
Trauma / Neurotrauma
Cause of Post-infectious and postvaccinal encephalomyelitis
Immunologic and demyelinating (neurologic or infectious in nature)
Arrange the components of a neurological examination (USUAL PRACTICE) in chronological order.
(1) Motor system
(2) Gait
(3) Cranial nerve exam
(4) Coordination / Cerebellar
(5) Sensory system
(6) Mental Status exam
(7) Reflexes
(6) Mental Status exam
(3) Cranial nerve exam
(1) Motor system
(4) Coordination / Cerebellar
(7) Reflexes
(5) Sensory system
(2) Gait
What is the tool used for sensory examination to check for equal sensations on the body?
Wartenberg Pin-Wheel
Name the sensory limb and the motor limb of the corneal reflex.
Sensory: Ophthalmic division of Trigeminal nerve
Motor: Facial nerve
Differentiate the affected areas of the face between stroke and bell’s palsy.
Stroke: Lower half of face
Bell’s Palsy: Whole half of face
TRUE OR FALSE: Air conduction is longer than bone conduction.
True.
Rinne’s Test and Weber’s Test are used to examine which cranial nerve?
Vestibulocochlear, Cranial nerve VIII
Shoulder shrug tests the (1) and head rotation tests the (2).
- Trapezius muscle
- Sternocleidomastoid muscle (Contralateral)
In a hypoglossal affectation, where is the tongue protruding/pushing?
Towards the weak / affected side
Fasciculations are (1) that are present in (2) and (3).
- Muscle twitches
2-3. Amyotrophic Lateral Sclerosis & Lower Motor Neuron disease
Semipurposeful flowing movements that flit from one part of the body to another. Chaotic or unpredictable movements. Swift grimaces and sudden movements of the head or limbs are examples of this condition.
Present in Huntington’s disease
Chorea
Wild, flinging/flailing movements that represent large amplitude proximal movements.
Rare form of involuntary movement confined to one side of the body.
Hemiballismus
Brief, sudden shock-life jerks, muscular contractions of a portion of a muscle, an entire muscle, or a group of muscles.
Patients with this condition can have seizures.
Myoclonus
Slow, sinuous, “snakelike”, writhing movements in distal limbs (fingers and toes).
Piano like movements in fingers & toes.
Athetosis
Alternating pronation-supination: Ask the patient to pronate and supinate the forearms rapidly.
This is a test for?
Dysdiadochokinesia
This test assesses unilateral hearing loss (conductive or sensorineural)
Weber’s Test
Eyebrow elevation, forehead wrinkling, eye closure, smiling, cheek puff, and whistling
can be used to examine which cranial nerve?
Facial nerve, cranial nerve VII
When testing this cranial nerve, the symmetry of nasolabial folds is examined at rest and at motion
Facial nerve, cranial nerve VII
We test the visual fields by —–.
Confrontation
Diagnostic test for muscle disease
Total Creatine Phosphokinase (CPK)
Diagnostic test for CNS infections (e.g. meningitis, encephalitis)
Lumbar puncture
TRUE OR FALSE: In papilledema, there’s clear disk margins, visible blood vessels, and double vision.
True
Frequent, Maintained/Sustained contraction of both agonist & antagonist muscles, frequently causing twisting & repetitive movements/abnormal postures. May present like a mannerism.
Dystonia
TRUE OR FALSE: When mapping a region of sensory loss, move from the affected area into the normal region
True
Steady resistance through the entire movement of a joint. An example is Parkinson’s disease
Rigidity
Diminished tone, suggests LMN disease
But may be observed acutely following UMN disease, such as stroke
Flaccidity
Clasp-knife reaction: When passive movement of a joint is attempted, —-produces resistance. The muscles, on stretching, suddenly give way due to neurotendinous organ-mediated inhibition.
Spasticity
Source: Snell
tone which is also velocity dependent but predictably increases with increased speed of movement and decreases at lower speeds
Paratonia
When asked to flex the neck, the whole body flexes except the neck
(+) neck rigidity
Segment/s of knee reflex
L2, L3, L4
Slow movements accompanied by tremors
Bradykinesia with tremors
Extremity tone indicative of UMN problem
Hypertonia
Assessing upper extremity strength and looking for pronator drift is part of which neuro exam?
Motor System
TRUE OR FALSE: CN VIII is affected in Bell’s Palsy along with CN VII.
False
Test for perception/conduction of air or bone
Rinne’s Test
TRUE OR FALSE: Distal sensorimotor deficit is present in a peripheral nerve problem.
True
TRUE OR FALSE: Examples of Inferior frontal lobe disease are meningioma/tumors that cause unilateral anosmia
True
TRUE OR FALSE: Gag reflex is checked by stimulating lateral pharyngeal wall on each side
FALSE. Posterior pharyngeal wall