S1: Cholinergic System Flashcards
1
Q
What does vecuronium do?
A
- It acts as an classical competitive antagonist
- Outcompetes acetylcholine for same binding site on Nic
- Therefore reduces stimulation
2
Q
What does suxamenthonium do?
A
- Agonist with poor dissociation
- Stays at synapse for a long time producing sustained EJP
- VgNA channels become inactivated due to continual absolute refractory period
- Prevents AP generation
- No contraction
3
Q
What do muscarinic agonist cause?
A
GI tract disturbances
Blurred vision
Excess salivation and sweating