S1: Cholinergic System Flashcards

1
Q

What does vecuronium do?

A
  • It acts as an classical competitive antagonist
  • Outcompetes acetylcholine for same binding site on Nic
  • Therefore reduces stimulation
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2
Q

What does suxamenthonium do?

A
  • Agonist with poor dissociation
  • Stays at synapse for a long time producing sustained EJP
  • VgNA channels become inactivated due to continual absolute refractory period
  • Prevents AP generation
  • No contraction
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3
Q

What do muscarinic agonist cause?

A

GI tract disturbances
Blurred vision
Excess salivation and sweating

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