RxPrep StudyGal Tips & Mnemonics

Question 1

G <3 PACMAN

common CYP inhibitors

Answer 1

Grapefruit
protease inhibitors
azole antifungals
cyclosporine, cobicistat
Macrolides (not azithro)
Amiodarone (dronedarone)
Non-DHP CCBs

Question 2

PS PORCS

Common CYP inducers

Answer 2

Phenytoin
Smoking
Phenobarbital
Oxcarbazepine
Rifampin
Carbamazepine
St. John’s wort

Question 3

Inducers

Answer 3

Super cops
smoking
U
Phenytoin
E
Rifampin
Carabmazepine (auto inducer)
OxcarbaRpine
Phenobarbital
St. John’s wort

Question 4

Inhibitors

Answer 4

Campaign
Cimetidine, cobicistat, cyclosporine
Azole antifumgals
Macrolides except azitjromyxin
Protease inhibitors
Amiodafone
I
Grapefruit
Non-DHP CCB

Question 5

Pgx- HLAB

Answer 5

Abacavir, carbamazepine, phenytoin
5701- hypersensitivity
1502- SJS TENS

Question 6

Pgx- factor v Leiden

Answer 6

Estrogen OC
risk of thromboembolic

Question 7

Pgx- cyp2c19

Answer 7

Clopidogrel, PPI
2/3 poor - alt
*17 rapid - higher dose

Question 8

Pgx- codeine (prodrug)

Answer 8

Ultra rapid- toxic
Poor - ineffective

Question 9

Pgx- cyp2d6 (tramadol)

Answer 9

Ultra rapid- ineffective
Pooor - toxicity

Question 10

Pgx- cyp2d6

Answer 10

Warfarin
2/3 med-poor - risk of bleed

Question 11

Pgx- cyp2a6

Answer 11

Nicotine
Poor - easier to quit, less dependency

Question 12

Pgx-ugt1a1

Answer 12

Irinotexan; promoter risk neutropenia

Question 13

Pgx- HER2

Answer 13

Trastuzumab, pertuzumab, lapatinib
Only use if her2 + over expression

Question 14

Pgx-kras

Answer 14

If kras +, do not use cetuximab, panitumumab