RXPREP Chapter 6: Controlled substances part 1 Flashcards
What does CSA stand for
controll substance act
- the DEA, under the DOJ, enforces the requirements in the CSA
the schedule is determined based on wheter the drug has currently accepted…
medical use,
its relative abuse potential
and the potential for it to cause dependence when abused
the higher the abuse potential the higher/lower the schedule number
lower
schedule I drugs have the highest abuse potential and are considered to have no accepted medical use
(heroin and LSD)
Schedule __-__ drugs are considered to have currently accepted medical uses
schedule II-V
What schedule?
no currently accepted medical use; high potential for abuse and lack of accepted safety under medical supervision
schedule I
what schedule?
high potential for abuse and may cause severe psychologiacl or physical dependence
schedule II
lower abuse potential than schedules I and II; abuse may cause moderate or low potential for physical dependence or high psychological dependence
schedule III
low potential for abuse relative to the next schedule, abuse may cause limited physical or psychological dependence
schedule IV
low potential for abuse relative it the next schedule, abuse may cause limited physical or psychological dependence relative to schedule IV
schedule V
MDMA GHB Heroin LSD Marijuana/Cannabis sativa mescaline peyote what schedule?
I
Alfentanil
codeine
fentanyl
hydrocodone, single ingredient
what schedule?
II
hydrocodone combo products
hydromorphone/ Diluadid
levorphanol
meperidine / Demerol
what schedule?
II
methadone/ Methadose
morphine / Kadian, MS Contin
oxycodone single ingredient/ OxyContin, Roxicodone
what schedule?
II
oxycodone combo products/ Endocet, Percocet, Percodan
oxymorphone
sufentanil
tapentadol
what schedule?
II
Actiq
what schedule?
fentanyl
II
Duragesic
what schedule?
fentanyl
II
Hysingla ER
what schedule?
hydrocodone
II
Zohydro ER
what schedule?
hydrocodone
II
Lortab, Norco, Tussicaps, Tussionex, vicodin, vicoprofen
what schedule?
hydrocodone combo products
II
Opana
what schedule?
oxymorphone
II
Nucynta, Nucynta ER
Tapentadol
II
Focalin, Focalin XR
what schedule?
amphetamine/dextro
II
Dexerdrine
what schedule?
dextroamphetamine
II
Cocaine
what schedule?
II
Dronabinol solution (Syndros)
what schedule?
II
Levo-alpha-acetyl-methadol (LAAM(
what schedule?
II
Phentobarbital
what schedule?
II
Secobarbital
what schedule?
Benzphetamine
what schedule?
III
Buprenorphine, single ingredient (Butrans)
III
Buprenorphine/naloxone (Suboxone)
III
Butabarbital
III
Butalbital (Fioicet with codeine, Fiorinal, Fiorinal with codeine)
III
Codiene/acetaminophen (tylenol with codeine #3, tylenol with codeine #4)
III
Dronabinol capsules (Marinol)
III
NOTE: solution (Syndros is schedule II)
Ketamine
III
Paregoric
III
Perampanel (Fycompa)
III
Phendimetrazine
III
Sodium oxybate (Xyrem)
III
Testosterone and all anaboolic steroids (look for andro)
Androderm, Androgel
III
What schedule are benzos?
IV
alprazolam/xanax, lorazepam/ativan, all the pams!
Chlordiazepoxide (Librium)
benzo
IV
Clobazam (Onfi)
benzo
IV
Klonopin
benzo, IV
Clorazepate (Tranxene-T)
benzo, IV
Diastat AcuDial, Valium
benzo, IV
Estazolam
benzo, IV
Flurazepam
benzo, IV
Versed
midazolam, IV
Byfavo
Remimazolam, IV
Restoril
Temazepam, IV
Halcion
Triazolam, IV
What schedule are hypnotics?
IV
Lunesta, Sonata, Ambien, Edluar, Zolpimist
IV
Suvorexant, Lemborexant, Zaleplon
IV
Weight loss drugs are what schedule?
IV
Adipex-P
Qysmia
Diethylpropion
Armodafinil/Nuvigil
Modafinil
schedule IV
Butorphanol (Stadol)
schedule IV
Carisoprodol (Soma)
schedule IV
Difenoxin/atropin
IV
eluxadolin
IV
Phenobarbital
IV
tramadol (Ultram)
tramadol/APAP (Ultracet)
IV
Brivacetam
V
Codeine containing cough syrups (codeine/promethazine, codeine/peomethazine/phenylephrine, codeine/guaifenasin)
V
Ceratussin AC
anything with AC
Diphenoxylate/atropine (Lomotil)
V
Lacosamide
V
Vimpat
PRegabalin
V
lyrica
when a schedule change occurs, a pharmacy must complete …
an inventory of the drug on the DATE of the changes becomes EFFECTIVE
barbiturate schedules–
a single entity oral formulation, such as pentobarbital is scheduled as:
when it is used in combination and formulated as a supposititory, schedule:
II
III
phenobarbital: IV
federally non control –> Fioricet, but iowa i think it is scheduled
Codeine schedules:
single entitiy products:
combination tablets/capsules:
combination cough syrups:
II
III
V
Dronabinol schedules:
Oral solution:
oral capsules:
II (Syndros)
III (Marinol)
The scheduling of some opioid-containing combintation drugs depends on the
opioid concentration compared to the other non-narcotic active ingredients
**we must know how to calculate the opioid concentration
if a drug exceeds the “not more than” quantity for schedule V, look to the next/more restrictive schedule cirtera
A drug will be classified as schedule ____ if the opioid quantity is NMT:
1.8g of codeine per 100mL or 90mg per dosage unit when combined with an equal or greater quantity of an isoquinoline alkaloid of opium
schedule III
rule of 3
A drug will be classified as schedule ____ if the opioid quantity is NMT:
1.8g of codeine per 100mL or 90mg per dosage unit when combined with one or more active non narcotic ingredient
schedule III
rule of 3
A drug will be classified as schedule ____ if the opioid quantity is NMT:
1.8g of dihydrocodeine per 100mL or 90mg per dosage unit when combined with one or more active non narcotic ingredient
III
rule of 3
A drug will be classified as schedule ____ if the opioid quantity is NMT:
50mg per 100mL or 100g per dosage unit when combined with one or more active non narcotic ingredient
III
rule of 3
A drug will be classified as schedule ____ if the opioid quantity is NMT:
1mg difenoxin and lot les than 25mcg of atropine sulfate per dosage unit
IV
A drug will be classified as schedule ____ if the opioid quantity is NMT:
200mg of codeine per 100mL or per 100g when combined with one or more active non nacotic ingredient (robitussin AC cough syrup)
V
rule of 5
A drug will be classified as schedule ____ if the opioid quantity is NMT:
100mg of dihydrocodeine per 100mL or per 100g when combined with one or more active non nacotic ingredient (dihydrocodeine/clorpheniramine/phenylephrine cough syrup)
V
rule of 5
A drug will be classified as schedule ____ if the opioid quantity is NMT:
2.5mg of diphenoxylate and not less than 25mcg of atropine sulfate per dosage unit (lomotil)
V
rule of 5
Epidiolex (cannabidiol) the first FDA approved CBD derived product that is indicated for seizures associated with several disorders, is what schedule?
NON-CONTROLLED. (containing no more than 0.1% (w/w) residual THC
Dronabinol (synthetic THC) is what schedule?
schedule II: syndros (oral solution)
schedule III (marinol oral capsule)
Nabilone (Cesamet) what schedule?
II
Legally, can CBD be extracted from hemp and used in topical products?
yes
FDA still regulates hemp and hemp-derived products, but they are no longer classified as schedule I – allows retail pharmacies to sell CBD containing topical products in select states