RX 260 Flashcards
- Symptoms of menopause
- Endometrial hyperplasia and carcinoma (polyp due to pro-estrogen effect in endometrium…weird)
Tamoxifen ADRs
Metronidazole ADRs (below diaphragm while Clinda is above)
- Rash, UTICARIA, YELLOW discoloration of the skin
- OPTIC NERVE DAMAGE
- N/V, dizziness, HA
Vancomycin ADRs
- “Red man syndrome”
- PHELBITIS
- Nephrotoxicity and ototoxicity
Ceftriaxone ADRs
-Elevated liver enzymes
-Pseudomembranous colitis
-Nephrotoxicity
(Hypersensitivity rxns, diarrhea, nausea)
Albuminocytologic dissociation (elevated protein, normal WBC count)
-Characteristic of GUILLAIN-BARRE syndrome
Stages of Shock: Class II
Blood loss: 15-30%
HR: Increased
BP: Normal
CNS symptoms: Anxious
Stages of Shock: Class IV
Blood loss: >40%
HR: Increased
BP: Decreased
CNS symptoms: Lethargic
Stages of Shock: Class III
Blood loss: 30-40%
HR: Increased
BP: Decreased
CNS symptoms: Confused
- Tachycardia one of earliest symptoms
- Sympathetic activation: vasoconstriction, cool mottled skin, hypothermia, acidosis, and diversion of blood from organs (like kidneys)
Hemorrhagic shock
Parinaud syndrome
- Pressure on pretectal region of midbrain
- Vertical gaze and pupil abnormalities
Enlarged adenoids and Morning headaches…
Sleep apnea in children
Pineoblastomas
- ICP due to OBSTUCTION OF CSF FLOW (main presenting symptom)
- May produce excess melatonin
- Pineal mass btw thalamic bodies
Diabetic Ketoacidosis
- Insulin deficiency and increase in glucagon
- Liver generates ketones
- Hyperglycemia osmotic diuresis→volume depletion→POLYDIPSIA and POLYURIA
- Hyperkalemia slash overall total body K+ deficit
Pseudohyponatremia
- Serum sodium is low but urine excretion of Na+ not increased
- Ex: Hyperglycemia→osmotic shift that pulls fluid from cells into the blood stream→Increase in fluid makes serum Na+ seem low but it really is the same
Clozapine (atypical) MOA and ADR (4)
- Blocks 5-HT and dopamine receptors
- AGRANULOCYTOSIS→severe reduction in WBC (WEEKLY blood monitoring for WBC count)
- Weight GAIN
- Seizures
- QT prolongation