Rutas metabólicas del colesterol Flashcards

1
Q

Productos del colesterol

A

1 sales biliares
2 Corticosteroides
3 Hormonas sexuales

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2
Q

Dónde se sintetiza el colesterol para formar sales biliares

A

Hígado

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3
Q

Enzima que con ayuda de NADPH transforma el COLESTEROL

A

7a-hidroxilasa dando como resultado 7a-hidroxicolesterol

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4
Q

cuantos tipos de ácidos biliares hay

A

Primarios y secundarios

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5
Q

Cuáles son los ácidos biliares primarios

A

Ac Cólico (+7a-deshidroxilasa)

Ac Quenodesoxicólico(+7a-deshidroxilasa)

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6
Q

Cuáles son los ac Biliares secundarios

A

ácido desoxicólico (previamente ac cólico)

ácido litocólico (previamente ácido quenodesoxicólico)

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7
Q

Cuál es el producto después de que las bacterias interactuan con el ac biliar secundario

A

Sales biliares: Glicina (Previamente ácido desoxicólico) y Taurina (previamente ácido litocólico)

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8
Q

(CORTICOIDES) Síntesis de colesterol para formar progesterona

A

Corteza suprarrenal

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9
Q

(CORTICOIDES) Zona glomerular

A

Aldosterona

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10
Q

(CORTICOIDES) Zona fascicular

A

cortisol

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11
Q

(CORTICOIDES) Zona reticular

A

Androstenediona

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12
Q

(CORTICOIDES) Colesterol entra a la mitocondria

A

Pregnenolona

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13
Q

(CORTICOIDES) pregnenolona sale de la mitocondria

A

progesterona

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14
Q

(CORTICOIDES) progesterona +17 a-hidroxilasa

A

17a-HIDROXIPROGESTERONA

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15
Q

(CORTICOIDES) 17a-Hidroxiprogesterona+21 hidroxilasa

A

11desoxicortisol

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16
Q

(CORTICOIDES) 11desoxicortisol+ Bhidroxilasa

A

cortisol (Zona Fascicular)

17
Q

(Mineralcorticoides) progesterona+21hidroxilasa

A

Aldosterona

18
Q

(Mineralcorticoides) Aldosterona

A

´Principal mineral corticoide (Zona glomerular)

19
Q

(Androgenos) Reduccion de androstenediana en 17c

A

testosterona

20
Q

(Androgenos) Estrogeno da lugar a

A

estrona, estradiol y estriol

21
Q

(Androgenos) testosterona +5a-reductasa

A

dihidrotestosterona

22
Q

(Androgenos) potencia de estrogenos

A

b-estradiol, estrona, estriol y a-estradiol