RSI Medications Flashcards

1
Q

Rocuronium Class

A

Neuro-Muscular Blocking Agent for paralysis

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2
Q

Suxamthonium Class

A

Neuro-Muscular Blocking Agent for paralysis

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3
Q

Fentanyl Class

A

Opioid (synthetic) Analgesic

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4
Q

Morphine Class

A

Opioid Analgesic

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5
Q

Midazolam Class

A

Benzodiazepine

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6
Q

Ketamine Class

A

General Anaesthetic

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7
Q

Propofol Class

A

General Anaesthetic

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8
Q

Fentanyl MOA

A

Binds to opioid receptors, results in hyperpolarisation of cells and inhibiition of nerves leading to reduced pain

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9
Q

Morphine MOA

A

Binds to mu-receptors of CNS and PNS, inhibits nocieceptive receptors reducing transmisson that reduces pain

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10
Q

Propofol MOA

A

Inhibits GABBA

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11
Q

Ketamine MOA

A

Interacts with NMDA, muscarinic, monoaminergic, opioid, voltage gated Ca receptors in brain producing dissociative/sedative state.

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12
Q

Midazolam

A

Acts on GABBA receptors, increasing activity that increases chloride channel opening producing muscle relaxation/anaesthesia

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13
Q

Suxamethonium MOA

A

Depolarising NMBA. Prolonged depolarisation of muscles to a membrane potential above what an action potential can be triggered. Causes vesiculations.

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14
Q

Rocuronium

A

Non-depolarising NMBA. Inhibits neuromuscular transmission by blocking acetylcholine at synaptic terminals preventing depolarization and muscle contraction

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15
Q

Fentanyl duration and half life

A

Onset 60seconds
Peaks 2-5minutes
Duration 30-60minutes
Half life 90minutes

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16
Q

Fentanyl preparation

A

100mcg/2ml + 8ml NaCl = 10mcg/10ml

500mcg/10ml + 40ml NaCl = 500mcg/50ml

17
Q

Fentanyl Contraindications

A

Allergy

Hepatic/renal impairment (pref then morph)

18
Q

Fentanyl side effects

A

Hypotension (in hypovolaemia)
N+V
RR depression

19
Q

Morphine preparation

A

10mg/1ml + 9ml NaCl = 10mg/10ml

10mg/1ml (x2) + 30mg + 47ml NaCl = 50mg/50ml

20
Q

Morphine Contraindications

A

RR depression

Serotonin Syndrome

21
Q

Morphine side effects

A
Bradycardia 
Hypotension 
CNS depression 
N+V 
Urinary retention
22
Q

Morphine duration and Half life

A

Onset 6-30minutes

Half-life 2-3hrs