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RSI Drugs Flashcards

1
Q

Generic name for Versed

A

midazolam

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2
Q

Common name for midazolam

A

Versed

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3
Q

midazolam (Versed) Class

A

CNS depressant, benzodiazepine, anticonvulsant, anxiolytic

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4
Q

midazolam (Versed) Indications

A

seizures, chemical restraint for psychotic episodes

sedation for RSI

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5
Q

midazolam (Versed) MOA

A

supresses seizures, reduces anxiety, relaxes skeletal muscles through short-term CNS depression

produces amnesia (RSI)

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6
Q

midazolam (Versed) Side Effects

A

respiratory depression, apnea, bradycardia, hypotension, drowsiness, nausea, vomiting, laryngospasms, bronchospasm, tachycardia, PVCs, blurred vision, headache, cough, altered loc, pain during injection, phlebitis

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7
Q

midazolam (Versed) Contraindications

A

allergic, hypotension, shock, acute narrow angle glaucoma, head injury, drug/ETOH on board

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8
Q

midazolam (Versed) Precautions

A

use flumazenil (Romazicon) to treat overdose unless convulsing or hx of seizures,support pt’s airway s/p severe respiratory depression, use caution when administering elderly/COPD/hepatic/renal pts, use caution when giving during MI s/p cardiogenic shock

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9
Q

midazolam (Versed) Interactions

A

using with CNS depressants or other benzos will potentiate (drastically increase) the effects

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10
Q

midazolam (Versed) Administration

A

Routes: SLOW IVP (1mg/min),IO, IM, IN

Onset: 1-3 min

Duration: 2-6 hrs (consider redose after 30 min)

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11
Q

midazolam (Versed) Dosage

A

0.01-0.05 mg/kg IV
(MAX 5mg per dose)

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12
Q

Generic name for Amidate

A

etomidate

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13
Q

Common name for etomidate

A

Amidate

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14
Q

etomidate (Amidate) Class

A

CNS depressant, anesthetic, sedative, hypnotic

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15
Q

etomidate (Amidate) Indications

A

cardioversion or pacing

sedation (RSI)

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16
Q

etomidate (Amidate) MOA

A

sedation, anesthesia, amnesia; short acting non-barbiturate

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17
Q

etomidate (Amidate) Side Effects

A

nausea, vomiting, hypotension, hypoventilation, apnea, dysrhythmias, laryngospasms

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18
Q

etomidate (Amidate) Contraindications

A

allergic, status asthmaticus, HIV/AIDS/transplants/chemo pts, adrenal issue pts (i.e. Addison’s Disease, suppresses the adrenal gland’s production of steroids)

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19
Q

etomidate (Amidate) Precautions

A

respiratory depression

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20
Q

etomidate (Amidate) Interactions

A

use with verapamil may increase CNS depression and anesthesia; use with diuretics, calcium channel blockers, and antihypertensives may increase hypotension; use with other CNS depressants increases sedative effects

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21
Q

etomidate (Amidate) Administration

A

Routes: SLOW IVP, IO

Onset: immediate

Duration: 3-5 minutes

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22
Q

etomidate (Amidate) Dosage

A

0.2-0.6 mg/kg SLOW IVP (over 1 min)

Common RSI dose: 20mg

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23
Q

Generic name for Ketalar

A

ketamine

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24
Q

Common name for ketamine

A

Ketalar

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25
Q

ketamine (Ketalar) Class

A

CNS depressant, anesthetic, sedative, dissociative hypnotic, analgesic

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26
Q

ketamine (Ketalar) Indications

A

pain management, chemical restraint, epileptic seizures, bronchodilator (COPD)

sedation prior to RSI (or other painful procedures, i.e. cardioversion, pacing)

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27
Q

ketamine (Ketalar) MOA

A

non-barbituate CNS depressant that causes profound anesthesia and analgesia without causing skeletal muscle relaxation or respiratory depression in proper doses, dissociative agent that allows pts to be awake but distant from pain

28
Q

ketamine (Ketalar) Side Effects

A

severe hallucinations, tachycardia, hypertension, hypersecretions, laryngospasm, drowsiness, nausea, vomiting

29
Q

ketamine (Ketalar) Contraindications

A

allergic, head injury

30
Q

ketamine (Ketalar) Precautions

A

ETOH on board, be prepared to handle severe hallucinations and psychosis when waking up

31
Q

ketamine (Ketalar) Interactions

A

CNS depressants increase the effects of ketamine

32
Q

ketamine (Ketalar) Administration

A

Routes: IV, IO, IM, IN

Onset: 3-5 min

Duration: 20-30 min

33
Q

ketamine (Ketalar) Dosage

A

Analgesia: 0.3-0.5 mg/kg IV
Behavior Management (restraint): 3mg/kg IM OR 1mg/kg IV

RSI Sedation: 1-2mg/kg IV or 4mg/kg IM

34
Q

Generic name for Anectine

A

succinylcholine

35
Q

Common name for succinylcholine

36
Q

succinylcholine (Anectine) Class

A

depolarizing neuromuscular blocker, paralytic

37
Q

succinylcholine (Anectine) Indications

38
Q

succinylcholine (Anectine) MOA

A

binds with cholinergic receptor sites at neuromuscular endplate and causes depolarization of skeletal muscle cells (fasciculations) followed by paralysis due to the continued binding of the receptor site and blockage of acetylcholine

39
Q

succinylcholine (Anectine) Side Effects

A

increased intraocular pressure, muscle stiffness or pain, hypotension, bradycardia, tachycardia, prolonged respiratory depression, bronchospasm, dysrhythmia, flushing of skin, hyperkalemia, malignant hyperthermia

40
Q

succinylcholine (Anectine) Contraindications

A

hypersensitivity, acute narrow angle glaucoma or penetrating eye injury (increases intraocular pressure), malignant hyperthermia, myasthenia gravis or other neuromuscular diseases

41
Q

succinylcholine (Anectine) Precautions

A

use caution in patients with burns, crush injuries, fractures, cardiac disease, respiratory disease, the elderly and children less than two years old

42
Q

succinylcholine (Anectine) Interactions

A

diazepam (Valium) may shorten duration; theophylline and cardiac glycosides may cause dysrhythmias; narcotics and oxytocin may increase neuromuscular blockade

43
Q

succinylcholine (Anectine) Administration

A

Route: IV, IO

Onset: 1 min

Duration: 6-10 min

44
Q

succinylcholine (Anectine) Dosage

A

1-1.5 mg/kg IV

45
Q

What is the Generic name for Zemuron

A

rocuronium

46
Q

What is the common name for rocuronium

47
Q

rocuronium (Zemuron) Class

A

non-depolarizing neuromuscular blocker, paralytic

48
Q

rocuronium (Zemuron) Indications

A

RSI, skeletal muscle relaxation

49
Q

rocuronium (Zemuron) MOA

A

competes for and binds with cholinergic receptor sites to inhibit neuromuscular transmission and cause paralysis

50
Q

rocuronium (Zemuron) Side Effects

A

hypotension, hypertension, respiratory depression, apnea, tachycardia, bronchospasms, urticaria, nausea, vomiting

51
Q

rocuronium (Zemuron) Contraindications

A

hypersensitivity

52
Q

rocuronium (Zemuron) Precautions

A

use caution in patients with hepatic or renal failure; will cause respiratory depression, be prepared to aggressively ventilate and intubate; does not cause sedation or analgesia, administer a benzodiazepine or narcotic prior to giving rocuronium to create sedation; use a combination of physostigmine, edrophonium and/or neostigmine to reverse the effects of rocuronium

53
Q

rocuronium (Zemuron) Interactions

A

use with succinylcholine (Anectine), anesthetics, lidocaine (Xylocaine), quinidine, procainamide (Pronestyl, Procan), beta blockers, diuretics and magnesium can prolong paralysis and respiratory depression

54
Q

rocuronium (Zemuron) Administration

A

Route: IV, IO, IVPB

Onset: 30-60 sec

Duration: 30-60 min

55
Q

rocuronium (Zemuron) Dosage

A

IV: 0.6-1.2 mg/kg (1mg/kg)
IVPB: 0.1-0.2 mg/kg/min

56
Q

What is the Generic name for Norcuron

A

vecuronium

57
Q

What is the common name for vecuronium

58
Q

vecuronium (Norcuron) Class

A

non-depolarizing neuromuscular blocker, paralytic

59
Q

vecuronium (Norcuron) Indications

60
Q

vecuronium (Norcuron) MOA

A

competes for and binds with cholinergic receptor sites to inhibit neuromuscular transmission and cause paralysis

61
Q

vecuronium (Norcuron) Side Effects

A

respiratory depression, apnea, prolonged paralysis

62
Q

vecuronium (Norcuron) Contraindications

A

hypersensitivity, myasthenia gravis and other neuromuscular diseases

63
Q

vecuronium (Norcuron) Precautions

A

use caution in patients with renal failure, pregnant women on magnesium sulfate and children younger than two years old; vecuronium does not cause sedation or analgesia; administer a benzodiazepine or narcotic prior to giving vecuronium to create sedation

64
Q

vecuronium (Norcuron) Interactions

A

use with narcotics or other neuromuscular blockers can prolong paralysis and respiratory depression; vecuronium is typically refrigerated

65
Q

vecuronium (Norcuron) Administration

A

Route: IV

Onset: 1 min

Duration: 30 min

66
Q

vecuronium (Norcuron) Dosage

A

0.1 mg/kg IV

Paramedic (1 decks)

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