RR - key associations Flashcards
Actinic (solar) keratosis
Precursor to squamous cell carcinoma
Acute gastric ulcer associated w/ CNS injury
Cushing’s ulcer (increased ICP stimulates vagal gastric secretion)
Acute gastric ulcer associated w/ severe burns
Curling ulcer (greatly reduced plasma volume results in sloughing of gastric mucosa)
Alternating areas of transmural inflammation and normal colon
Skip lesions (Crohn’s)
Aneurysm, dissecting
Hypertension
Aortic aneurysm, abdominal and descending aorta
Atherosclerosis
Aortic aneurysm, arch
Tertiary syphilis, vasa vasorum destruction
Aortic aneurysm, ascending
Marfan’s (idiopathic cystic medial degeneration)
Atrophy of mammillary bodies
Wernicke’s encephalopathy (thiamine deficiency causing ataxia, ophthalmoplegia and confusion)
Autospenectomy (fibrosis and shrinkage)
Sickle cell
Bacteria associated with gastritis, peptic ulcer disease and stomach cancer
H. pylori
Bacterial meningitis (adults and elderly)
S. pneumo
Bacterial meningitis (newborns and kids)
Group B strep (newborns), S. pneumo/N. meningitidis (kids)
Bleeding disorder with GpIb deficiency
Bernard soulier syndrome (defect in platelet adhesion to vW factor)
Brain tumor (adults)
Supratentorial: metastasis > astrocytoma (including GBM) > meningioma > schwannoma
Brain tumor (kids)
Infratentorial: medulloblastoma (cerebellum)
Supratentorial: craniopharyngioma
Breast cancer
Infiltrating ductal carcinoma (in the US, 1 in 9 women will develop breast cancer)
Breast mass
Fibrocystic change, carcinoma (in postmenopausal women)
Breast tumor (benign)
Fibroadenoma
Cardiac primary tumor (kids)
Rhabdomyoma, often seen in tuberous sclerosis
Cardiac manifestation of lupus
Libman-Sacks endocarditis (nonbacterial, affecting both sides of mitral valve)
Cardiac tumor (adults)
Metastasis, primary myxoma (4:1 left to right atrium; “ball and valve”)
Cerebellar tonsillar herniation
Chiari malformation (often presents with progressive hydrocephalus or syringomyelia)
Chronic atrophic gastritis (autoimmune)
predisposes to gastric carcinoma (can also cause pernicious anemia)
Clear cell adenocarcinoma of the vagina
DES exposure in utero
Compression fracture
Osteoporosis (type 1: postmenopausal; type 2: elderly man or woman)
Congenital adrenal hyperplasia, hypotension
21-hydroxylase deficiency
Congenital cardiac anomaly
VSD
Congenital conjugated hyperbilirubinemia (black liver)
Dubin Johnson (inability of hepatocytes to secrete conjugated bilirubin into bile)
Constrictive pericarditis
Tuburculosis (developing world); SLE (developed world)
Coronary artery involved in thrombosis
LAD > RCA > LCA
Cretinism
Iodine deficit/hypothyroid
Cushing’s syndrome
Iatrogenic cushings (from corticosteroid therapy)
Adrenocortical adenoma
ACTH secreting pituitary adenoma
Paraneoplastic Cushing’s (due to ACTH from other tumors)
Cyanosis (early, less common)
Tetralogy of Fallot, transposition, truncus (also TAPVR and tricuspid atresia)
Cyanosis (late, more common)
VSD, ASD, PDA
Death in CML
Blast crisis
Death in SLE
Lupus nephropathy
Dementia
Alzheimer’s, multiple infarcts
Demyelinating disease in young women
MS
DIC
Severe sepsis, obstetric complications, cancer, burns, trauma, major surgery
Dietary deficit
Iron
Diverticulum in pharynx
Zenker’s (diagnosed by barium swallow)
Ejection click
Aortic/pulmonic stenosis
Esophageal cancer
Squamous (worldwide), adeno (USA)
Food oisoning (exotoxin mediated)
S. auerus, B. cereus
Glomerulonephritis (adults)
Berger’s IgA nephropathy
Gynecologic malignancy
Endometrial carcinoma (USA), cervical carcinoma (worldwide)
Heart murmur, congenital
Mitral valve prolapse
Heart valve in bacterial endocarditis
Mitral>aortic (rheumatic fever), tricuspid (IV drug abuse)
Helminth infection (US)
Enterobius vermicularis, ascaris lumbricoides
Hematoma-epidural
Rupture of middle meningeal artery (trauma, lentiform shaped)
Hematoma-subdural
Rupture of bridging veins (crescent shaped)