Routes of Administration, Onset Of Action, Peak Effect, Duration Of Action Flashcards
ABIXIMAB
route of administration, onset of action, peak effects & duration
Routes of Administration: Intravenous bolus followed by infusion
Onset of Action: A few minutes
Peak Effects: In less than 30 minutes
Duration of Action: Two phased elimination results in restoration of platelet function to >50% after 24 hours, approximately 85% after 48 hours and low levels of GP IIb/IIIa receptor blockade present for up to 10 days post infusion.
ACETYLSALICYLIC ACID, ASPIRIN, ASA
route of administration, onset of action, peak effects & duration
Routes of Administration: Oral
Onset of Action: 20-30 minutes
Peak Effects: 2 hours
Duration of Action: 4-6 hours
ACETYLSALICYLIC ACID, ASPIRIN, ASA (EMT Administration)
route of administration, onset of action, peak effects & duration
Routes of Administration: Oral
Onset of Action: 20-30 minutes
Peak Effects: 2 hours
Duration of Action: 4-6 hours
ADENOSINE
route of administration, onset of action, peak effects & duration
Routes of Administration: Rapid IV push
Onset of Action: Seconds
Peak Effects: Seconds
Duration of Action: 10-12 seconds (1/2 life 5 seconds)
ALUTEROL SULFATE
route of administration, onset of action, peak effects & duration
Routes of Administration: Nebulized, mouth piece or in-line via mask Inhaler, patients own ET/NT in-line
Onset of Action: 5-15 minutes
Peak Effects: 30 minutes - 2 hours
Duration of Action: 3-4 hours
AMIODARONE
route of administration, onset of action, peak effects & duration
Route of Administration: IV/IO bolus, IV/IO infusion
Onset of Action: Variable
Peak effects: Variable
Duration of Action: Half-life may exceed 40 days.
ATROPINE SULFATE
route of administration, onset of action, peak effects & duration
Routes of Administration: Intravenous, intraosseous, intrathecal, or intramuscular (using AtroPen); okay for endotracheal use if necessary.
Onset of Action: Rapid, 1 minute
Peak Effects: IV – 2-5 minutes IM – 30 minutes
Duration of Action: Half-life – 2 to 3 hours Terminal half-life – 12.5 hours
BUMETANIDE
route of administration, onset of action, peak effects & duration
Onset of Action: IV – immediate
Peak Effect: IV – 15 to 30 minutes
Duration of Action: 2 to 4 hours
CALCIUM CHLORIDE
route of administration, onset of action, peak effects & duration
Routes of Administration: IV bolus
Onset of Action: Seconds
Peak Effects: 3 - 5 minutes
Duration of Action: 15-30 minutes
CALCIUM GLUCONATE GEL, 2.5%
route of administration, onset of action, peak effects & duration
Onset of Action: Immediate
Peak Effects: Unknown
Duration of Action: Unknown
CHARCOAL, ACTIVATED (without sorbitol)
route of administration, onset of action, peak effects & duration
Routes of Administration: Oral (po), nasogastric tube (ng), orogastric (og)
Onset of Action: Immediate
Peak Effects: Not applicable
Duration of Action: Dependent upon GI function; acts until excreted
CIMETIDINE
route of administration, onset of action, peak effects & duration
Routes of Administration:
IV infusion – Piggy back
Onset of Action: Unknown
Peak Effects: Immediate
Duration of Action: Unknown
DEXAMETHASONE SODIUM PHOSPHATE
route of administration, onset of action, peak effects & duration
Routes of Administration: IV/IO/IM
Onset of Action: 4-8 hours
Peak Effects: 6-12 hours
Duration of Action: 24-72 hours
DEXTROSE 50%
route of administration, onset of action, peak effects & duration
Routes of Administration: IV bolus (rapid)
Onset of Action: Seconds
Peak Effects: Variable
Duration of Action: Variable
DIAZEPAM
route of administration, onset of action, peak effects & duration
Routes of Administration:
Slow IV push
Rectally for children < 6 years
Onset of Action: Minutes
Peak Effects: Minutes
Duration of Action:
20 minutes to 50 minutes
DILTIAZEM
route of administration, onset of action, peak effects & duration
Route of Administration: Intravenous bolus(es) followed by a maintenance infusion
Continuous infusion for maintenance
Dosage: 5 to 10 mg/hr initially; may be adjusted to 15mg/hr if needed
Onset of Action: IV - immediately
Peak Effects: IV - 2 hours or less
Duration of Action: IV - 4 to 6 hours
DIPHENHYDRAMINE HCL
route of administration, onset of action, peak effects & duration
Routes of Administration: IV/IO, Deep IM
Onset of Action: IV 5 - 10 minutes
Peak Effects: 1 hour
Duration of Action: 3-6 hours
DOPAMINE
route of administration, onset of action, peak effects & duration
Routes of Administration: IV infusion
Onset of Action: Almost immediate, upon presentation to central circulation
Peak Effects: 5-10 minutes
Duration of Action: Effects cease almost immediately when infusion is shut off
EPINEPHRINE AUTO-INJECTOR
route of administration, onset of action, peak effects & duration
Route of Administration: IM, only into the anterolateral aspect of the thigh (through clothing if necessary)
Onset of Action: Seconds
Peak Effects: Minutes
Duration of Action: Several minutes
EPINEPHRINE HCL
route of administration, onset of action, peak effects & duration
Routes of Administration:
Cardiac: IV push, IV infusion, ET, or IO
Asthma/anaphylaxis/bronchiolitis: IM, SC, SL injection, IV, ET, IO
Onset of Action: Seconds
Peak Effects: Minutes
Duration of Action: Several minutes
EPTIFIBATIDE
route of administration, onset of action, peak effects & duration
Routes of Administration: Intravenous bolus followed by infusion
Onset of Action: A few minutes
Peak Effects: Early peak in less than 30 minutes, infusion steady state peak in 4 to 6 hours.
Duration of Action: Platelet function restores 2 to 4 hours after eptifibatide infusion is discontinued
ETOMIDATE
route of administration, onset of action, peak effects & duration
Route of Administration: IV
Onset of Action: 1 minute
Duration of Action: 3-5 minutes
FAMOTIDINE
route of administration, onset of action, peak effects & duration
Routes of Administration: IV infusion – Piggy back
Onset of Action: 1 hour
Peak Effects: 1-4 hours
Duration of Action: 12 hours
FENTANYL CITRATE
route of administration, onset of action, peak effects & duration
Routes of Administration: Usually given IV/IO in the field, can be given IM or IN.
Peak Effects: Within 5-15 minutes when given IV/IO/IN. Less predictable when given IM. Peak respiratory depressant effect within 5-15 minutes after onset of analgesic effect.
FUROSEMIDE
route of administration, onset of action, peak effects & duration
Routes of Administration: Slow IV push
Onset of Action: 5 minutes (vasodilation)
Peak Effects: 20-60 minutes (diuresis)
Duration of Action: Variable
GLUCAGON
route of administration, onset of action, peak effects & duration
Routes of Administration: Hypoglycemia: IM or SC administration avoids possibility of inducing encephalopathy in a thiamine-deficient patient
Onset of Action: (dose and route dependent)
1 mg IM, 8-10 minutes IV, 1 minute
Peak Effects: (does and route dependent)
1 mg IM, 12-14 minutes IV, 3-6 minutes
Duration of Action: (dose and route dependent)
1 mg IM, 12-27 minutes IV, 20 minutes
HEMOSTATIC AGENTS
route of administration, onset of action, peak effects & duration
Routes of Administration: Topical gauze or dressing
Onset of Action: Immediate
Peak Effects: 5 minutes
Duration of Action: Unknown
