Routes of administration

Question 1

What is enteral dosage form

Answer 1

Through the GI tract

Question 2

What is rectal

Answer 2

Through the anus

Question 3

What are parental

Answer 3

Given through tissue

Question 4

What is respiratory

Answer 4

Drugs that are inhaled through the respiratory system

Question 5

Local

Question 6

What is sublingual administration

Answer 6

Drug is placed under the tongue

Question 7

What is buccal administration

Answer 7

The drug is placed on the surface of the cheek

Question 8

What is the peroral route

Answer 8

When a drug enters through the mouth into the GI tract then through the hepatic portal vein into the liver before entering circulation

Question 9

What is the primary absorption site of the GI tract

Answer 9

The duodenum, it has a large SA due to the villi and microvilli.

Question 10

Disadvantages of the oral delivery

Answer 10

Incomplete absorption and the hostile environments of the GI tract may alter the drug

Question 11

Advantages of the rectal route

Answer 11

Can be used when patient is unable to take oral route e.g. vomiting. Also when doesn’t pass through the liver.

Question 12

Disadvantages to the rectal route

Answer 12

Absorption isn’t consistent

Question 13

What are the three main types of parental administration

Answer 13

Intravenous, intramuscular and subcutaneous

Question 14

What is subcutaneous

Answer 14

Injection into the fatty tissue under the skin. Low vascularity so slow absorption

Question 15

What is intrathecal

Answer 15

Injection into the spinal cord

Question 16

What is intraarticular

Answer 16

Into a joint

Question 17

What is intravitreal

Answer 17

Injection into the eyes

Question 18

What intra-osseous

Answer 18

Into the marrow of long bones

Question 19

What is intra-dermal

Answer 19

Into the upper layer of skin

Question 20

What is intra-peritoneal

Answer 20

Into the peritoneal, (the area that contains abdominal muscles)

Question 21

What are the two types of IV injection

Answer 21

Bonus and infusion
Bonus is injecting the blood stream with a drug to have an immediate effect
Infusion is constant input into the veins e.g. plasma drug

Question 22

What is intra-arterial

Answer 22

Injecting into a specific artery to create a high concentration in that specific area before distribution int the rest of the body.

Question 23

What is intramuscular

Answer 23

Injecting into a skeletal muscle. The rate of absorption dependant on the vascular it’s of the muscle. Long lasting action.

Question 24

Topical route

Answer 24

Drug is applied onto the surface of the skin. Non invasive and absorption varies depending on the site of application

Question 25

Intranasal

Answer 25

Drug is administered into the nose

Question 26

Advantages of Intranasal

Answer 26

Rapid absorption, safe, non-invasive, easy to administer and avoids the kidney.

Question 27

Disadvantages of nasal administration

Answer 27

Mucus eliminates the drug, nasal congestion wit colds and improper administration techniques lower absorption

Question 28

What is pulmonary absorption (periorally)

Answer 28

When drugs are absorbed into the lungs through the mouth

Question 29

Disadntages of the

Question 29

Disadntages of the