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Psych shelf > Round 3 > Flashcards

Round 3 Flashcards

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1
Q

What is the Schizophrenia prevalence in the general population?

A

0.5%-1%

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2
Q

What is the Schizophrenia prevalence for a sibling?

A

10%

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3
Q

What is the Schizophrenia prevalence for a monozygotic twin?

A

50%

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4
Q

What drug is purple gray metallic rash over sun exposed areas and jaundice?

A

Chlorpromazine

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5
Q

What drug is prolonged QTc and pigmented retinopathy?

A

Thioridazine

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6
Q

If a patient has drug induced Parkinsonism, what do you not give?

A

L-Dopa

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7
Q

What is the incidence of bipolar in the general population?

A

1%

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8
Q

What is the incidence of bipolar in a brother who’s brother has bipolar?

A

80-90%

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9
Q

What stroke would cause bipolar in an older adult?

A

Right Frontal Hemisphere stroke

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10
Q

Possible EKG signs of Lithium?

A

T-wave flattening and U-waves

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11
Q

What is the atypical agent with highest risk of EPS and increased prolactin?

A

Risperidone

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12
Q

What atypical is weight neutral but prolongs QTc, anti-psychotic?

A

Ziprazodone

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13
Q

What atypical is weight neutral but increases akathisia?

A

Aripiprazole

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14
Q

Which atypical agent is associated with weight gain?

A

Olanzapine

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15
Q

Which anti-psychotic can cause orthostasis and cataracts?

A

Quietiapine (alpha blocking properties)

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16
Q

What are the two lab values to worry about for clozapine?

A

WBC less than 3000 and ANC less than 1500

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17
Q

What sex based thing can SSRIs be used for?

A

Premature Ejaculation

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18
Q

What three drugs can really cause depression?

A

IFN-gamma, methyl-dopa, and Beta Blockers

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19
Q

Left Middle Cerebral Artery, what can that cause?

A

Depression

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20
Q

What SSRI has the most drug-drug interactions?

A

Paroxetine

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21
Q

What SSRI do you not have to taper, due to a short half life?

A

Fluoxetine

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22
Q

What SSRI has the fewest drug-drug interactions?

A

Citalopram

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23
Q

What is the rationale for depression and sleep issues?

A

Depression decreases REM latency, the faster I get into REM the more REM I have, and the less rested, I am

Your body rests best not in REM, slow wave sleep

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24
Q

SSRI discontinuation syndrome, what is the most common drug that can cause it? Name 2

A

Sertraline and Fluvoxamine

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25
Q

What can you not give bupropion too?

A

Alcoholics, Bulimia, and Epileptics

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26
Q

Venlafaxine is bad for what type of patients? Particularly with St. John’s wort

A

Hypertension patients

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27
Q

Hypertensive crisis with MAOi, what do I use?

A

Phentolamine 5 mg

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28
Q

What is leaden paralysis in the morning, sleeping more and gaining weight?

How is it best treated?

A

Atypical Depression, can affect social functioning

Treated best with MAOi

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29
Q

Children, age 1-3, what are they big for?

A

Object Permanence, objects are there even when they cannot be seen

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30
Q

Children, age 3-5, what are they big for?

A

Pre-operational egocentric, child can only understand his perspective, not another perspective

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31
Q

Children, age 6-11, what are they big for?

A

Concrete Operational, death is permanent

32
Q

Children, age 11 and above, what are they big for?

A

Children can learn to think abstractively

33
Q

Macrocephaly, long face, and macroorchism, young child, mentally handicapped, what is this?

A

Fragile X

34
Q

Café-au-laitspots, seizures large head. Autosomal dominant

A

Neurofibromatosis

35
Q

Coarse facies, short stature, cloudy cornea. Autosomal recessive.

A

Hurler Syndrome

36
Q

Broad, square face, short stature, self-injurious behavior. Deletion on Chr17

A

Smith Magenis

37
Q

Hypotonia, hypogonadism, hyperphagia, skin picking, agression. Deletion on paternal Chr15.

A

Prader-Willi

38
Q

Seizures, strabismus, sociable w/ episodic laughter. Deletion on maternal Chr15.

A

Angelman

39
Q

Elfin-appearance, friendly, increased empathy and verbal reasoning ability. Deletion on Chr7.

A

Williams

40
Q

ADHD-like sxs, microcephaly, smooth philtrum. Most common cause of mental retardation.

A

Fetal Alcohol Syndrome

41
Q

Seizures, chorioretinitis, hearing impairments, periventricular calcifications, petechiae@ birth, hepatitis.

A

Congenital CMV infection.

42
Q

Seizures, hearing impairments, cloudy cornea/retinitis, heart defects, low birth weight.

A

Congenital Rubella Syndrome

43
Q

Abnormal muscle tone, unsteady gait, seizures, mental retardation or learning disability.

A

Cerebral Palsy from birth asphyxia.

44
Q

IUGR, hypertonia, distinctive facies, limb malformation, self-injurious behavior, hyperactive.

A

Cornelia de Lange

45
Q

Coloboma, heart defects, choanal atresia, growth retardation, GU anomalies, ear deformity and deafness. Chr8.

A

Charge Syndrome

46
Q

Autism spectrum sxs, heart disease, palate defects, hypopastic thymus, hypoCa. Chr22 deletion.

A

DiGeorge Syndrome

47
Q

Vomiting, seizures, lethargy, coma. Acidosis w/ stress, illness. Causes neurological damage.

A

Maple Syrup Urine Disease

48
Q

Exclusively in girls, normal development for 6-8mo, then regression, handwringing, loss of speech and use of hands. X-linked dominant deletion of MECP2.

A

Rett Syndrome

49
Q

Normal development until age 2 then major loss of verbal, social skills w/ autistic like behavior.

A

Childhood Disintegrative Disorder

50
Q

Lack of mother-child eye contact, language delay/repetitive language, pre-occupation w/ “parts of toys” before age 3.

A

Autism

51
Q

Problems with social skills (usually recognized in preschool) w/ reserved verbal ability.

A

Asperger

52
Q

Methylphenidate, what is the MOA?

What disease is it used in?

A

Blocks DA reuptake

ADHD

53
Q

Amphetamine, what is the MOA?

What disease is it used in?

A

Blocks DA/NE reuptake

ADHD

54
Q

Atomoxetine, what is the MOA?

What disease is it used in?

A

NE reuptake inhibitor

Non stimulant****
ADHD

55
Q

Clonidine, Guanfacine, what is the MOA?

What disease is it used in?

A

Alpha 2 agonists, reduce peripheral SNS

ADHD

56
Q

Tic disorder, what is the first line drug?

What is most effective?

A

Clonidine

Haloperidol/Pimozide Dopamine Receptor Antagonists

57
Q

7 year old complains of frequent abdominal pain resulting in many missed school days. He never gets the pain on the weekends or in the summer. What disorder is this?

A

Separation Anxiety Disorder

58
Q

6 year old adopted child is brought in because she has not formed a relationship with her adoptive parents. She is inhibited and hyper vigilant. What disorder is this?

A

Reactive Attachment Disorder

59
Q

An 18mo old baby has recently been regurgitating and re-chewing her food. She had previously been eating normally. What disorder is this?

A

Rumination Disorder

60
Q

Patient has dementia, motor dysfunction, and dysarthria, what disease is this?

What is the anatomical problem?

A

Marchiafava-Bignami Disease

Corpus Callosum problem, and surrounding white matter problems

Chronic Alcohol use induced

61
Q

What is a disorder of anterograde amnesia, disorientation that lasts less than a day, is reversible, and is not associated with a comorbidity?

A

Transient Global Amnesia

62
Q

Dissociative Amnesia usually involves what?

A

Trauma to the person, has to go past more than the event itself

63
Q

How long do we need illness anxiety disorder to make this a thing?

A

6 months

64
Q

What is low in CSF that is increased with aggression and impulsiveness?

A

Serotonin

65
Q

If I was going to win a long time Benzo, what would I most likely have?

A

Insomnia

66
Q

What is the DOC for narcolepsy?

A

Sodium Oxybate

67
Q

What is used for RLS?

A

Dopamine agonists and Benzodiazepines

68
Q

How long should I wait after an MAOi to use an SSRI?

A

2 weeks

69
Q

Which SSRI is most likely to cause weight gain?

A

Paroxetine

70
Q

What pathway is positive symptoms?

A

Mesolimbic

71
Q

What pathway is negative symptoms?

A

Mesocortical

72
Q

What is lamotrigine used for?

A

Bipolar Depression

73
Q

What is the not so good side effect of Amitriptyline?

A

Visual hallucinations

74
Q

When I have fast EEG activity, what do I have?

A

Delirium Tremens

75
Q

When I have delirium from too many girl scout cookies, what does my EEG look like?

A

Diffuse Background on EEG

76
Q

What patients are very sensitive to EPS symptoms and should not be given anti-psychotics?

A

Lewy Body Dementia

77
Q

What is the strong emotional reaction patients may experience when retrieving traumatic memories?

A

Abreaction

Psych shelf (3 decks)

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