Rotation 3 pharm quiz

Question 1

Dosage forms of atenolol

Answer 1

25 mg
50 mg
100 mg

Question 2

Average daily dosages of atenolol

Answer 2

HTN: 50-100 mg daily

Angina pectoris: 50-200 mg daily

Question 3

Common indications for atenolol

Answer 3

HTN

Angina pectoris

Question 4

MOA of atenolol

Answer 4

Cardioselective beta-1 adrenergic receptor blocker which results in decreased HR and CO

Question 5

Common SEs of atenolol

Answer 5

Drowsiness
Dizziness
Bradycardia
Hypotension
Fatigue

Question 6

Renal or hepatic dosage adjustments for atenolol

Answer 6

Renal: CrCl 15-35: max dose 50 mg/day

CrCl <15: max dose 25 mg/day

Question 7

BBW for atenolol

Answer 7

Withdrawn abruptly can cause acute tachycardia, HTN, and/or ischemia

Question 8

Clinically significant drug interactions for atenolol

Answer 8

May decrease effect of clonidine

Verapamil increases toxicity effect of atenolol

Question 9

Major counseling points of atenolol

Answer 9

May mask hypoglycemic sx in pt with DM.
Use caution while operating machinery or when mental alertness is required.
Rise slowly when standing up from sitting and lying position.
Do not abruptly d/c

Question 10

Monitoring parameters of atenolol

Answer 10

BP

HR

Question 11

Dosage forms of montelukast

Answer 11

Tablets 10 mg
Chewable tablets 4 mg, 5 mg
Granules 4 mg per foil packet

Question 12

Average daily doses of montelukast

Answer 12

Adolescents and adults 15 yrs of age and older: one 10 mg tablet daily to be taken in the evening

Question 13

Common indications for montelukast

Answer 13

Prophylaxis and chronic tx of asthma and adults and children 2 yrs of age and older.
Relief of seasonal rhinitis and perennial allergic rhinitis
Prevention of exercise-induced bronchoconstriction

Question 14

MOA of montelukast

Answer 14

Selective leukotriene receptor antagonist that inhibits the cysteinyl leukotriene receptor

Question 15

Common AEs of montelukast

Answer 15

HA
Influenza
Cough
Abd pain
Dyspepsia
Dizziness

Question 16

Clinically sig drug interactions of montelukast

Answer 16

Phenobarbital may increase metabolism

May decrease the metabolism of paclitaxel, rosiglitazone, and repaglinide

Question 17

Major counseling points for montelukast

Answer 17

Indicated for chronic tx of asthma and should be taken regularly even when the pt is asymptomatic. Not intended to treat asthmatic attacks.
Singulair granules can be given either directly in the mouth or mixed with a spoonful of soft food

Question 18

Monitoring parameters for montelukast

Answer 18

FEV1
Peak flow
Unusual changes in mood
Improvement in S/Sx of asthma

Question 19

Dosage forms of clonazepam

Answer 19

Tablets 0.5 mg, 1 mg, 2 mg

Orally-disintegrating wafers 0.125 mg, 0.5 mg, 1 mg, 2 mg

Question 20

Average daily dosages of of clonazepam

Answer 20

1.5-2 mg daily

Question 21

Common indications for clonazepam

Answer 21

Lennox-Gastaut syndrome
Akinetic and myoclonic seizures
Absence seizures with succinimide failure
Panic disorder
GAD

Question 22

MOA of clonazepam

Answer 22

Binds to and enhances activity of GABA receptors

Question 23

Common AEs of clonazepam

Answer 23

Drowsiness
Ataxia
Fatigue
Dizziness

Question 24

Clinically significant drug interactions of clonazepam

Answer 24

Increased CNS depression with EtOH and other CNS depressants

Caution in pts taking opioids d/t increased risk of sedation and resp depression

Question 25

Major counseling points of clonazepam

Answer 25

May cause drowsiness Avoid EtOH while taking this medication May be habit-forming Do not stop taking this med abruptly Store in a cool dry place away from kids and sunlight If a dose is missed, take it ASAP If it is closer to the time of your next dose, skip the missed dose and return to nl dosing schedule- do not double doses

Question 26

Monitoring parameters of clonazepam

Answer 26

Improvement in sx of anxiety | Misuse, abuse, decreased seizure activity

Question 27

Dosage forms of penicillin

Answer 27

Powder: 125 mg/5 mL, 250 mg/5 mL Tablet: 250 mg, 500 mg

Question 28

Average daily dosages of penicillin

Answer 28

250- 1,000 mg/day

Question 29

Common indications of penicillin

Answer 29

Various infections

Question 30

MOA of penicillin

Answer 30

Inhibits cell wall mucopeptide biosynthesis

Question 31

Common AEs of penicillin

Answer 31

Black tongue Diarrhea Vomiting

Question 32

Renal or hepatic dose adjustments for penicillin

Answer 32

Consider dose adjustments with either renal or liver failure

Question 33

Clinically sig drug interactions with penicillin

Answer 33

May result in an increased INR when taken by a warfarin pt

Question 34

Major counseling points for penicillin

Answer 34

Take till empty | May effect the effectiveness of contraceptives

Question 35

Monitoring parameters of penicillin

Answer 35

Improvement in S/Sx of infection, WBC

Question 36

Dosage forms of Augmentin

Answer 36

PO suspension Tablets Tablets ER Tablets chewable

Question 37

Average daily doses of Augmentin

Answer 37

875 mg every 12 hrs

Question 38

Common indications of Augmentin

Answer 38

Tx of OM, sinusitis, and infections caused by susceptible organisms involving the lower resp tract, skin and skin structure, and urinary tract

Question 39

Common AEs of Augmentin

Answer 39

Diarrhea GI upset Vomiting

Question 40

Renal or hepatic dose adjustments for Augmentin

Answer 40

Renal- CrCl 10-30: dose every 12 hrs, CrCl <10: dose every 24 hrs. Do not use ER tablets in pts with hemodialysis

Question 41

Major counseling points of Augmentin

Answer 41

``` Do not skip any doses Take with food Refrigerate suspension If a rash develops contact physician Ask for PCN allergy ```

Question 42

Monitoring parameters of Augmentin

Answer 42

Improvement of S/sx of infection, WBC

Question 43

Dosage forms of meloxicam

Answer 43

Tablets 7.5 mg, 15 mg | Oral suspension 7.5 mg/5 mL

Question 44

Average daily dosages of meloxicam

Answer 44

7.5-15 mg daily

Question 45

Common indications for meloxicam

Answer 45

OA | RA

Question 46

MOA of meloxicam

Answer 46

Inhibits cylooxygenase resulting in a decreased biosynthesis of prostaglandins

Question 47

Common AEs of meloxicam

Answer 47

``` Abd pain Diarrhea Dyspepsia Flatulence Nausea ```

Question 48

Renal or hepatic dosage adjustments for meloxicam

Answer 48

Caution with sig renal and hepatic impairment

Question 49

BBW for meloxicam

Answer 49

Use is contraindicated for tx of perioperative pain in the setting of CABG surgery. Associated with an increased risk of adverse cardiovascular thrombotic events (MI, stroke) Increased risk of GI irritation, inflammation, ulceration, bleeding, and perforation

Question 50

Clinically sig drug interactions of meloxicam

Answer 50

Increase risk of bleeding in pts taking warfarin and other NSAIDs Chronic use with NSAIDs and SSRIs/SNRIs increase risk of GI bleeds

Question 51

Major counseling points of meloxicam

Answer 51

Avoid EtOH and concomittant use of other NSAIDs | May require up to 2 wks to see noticeable improvement in arthritic conditions.

Question 52

Monitoring parameters of meloxicam

Answer 52

Improvement in inflammation/pain