Rosh Material #3 Flashcards

1
Q

age requirements for dx of antisocial pd

A

adults >18 w. symptoms occurring since age 15

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2
Q

t/f: pharm is not generally recommended for antisocial pd

A

t!

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3
Q

categories of EPS

A

dystonia
parkinsonism
akathisia
TD

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4
Q

compulsive repetitive motions
agitation

A

akathisia

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5
Q

lip smacking
worm-like tongue movements
fly-catching

A

TD

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6
Q

pharm for acute dystonias (spasms of tongue, neck, face, back)

A

diphenhydramine

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7
Q

tx for akathisia

A

propranolol

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8
Q

tx for parkinsonism EPS

A

amantadine

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9
Q

parenteral exposure to what agent is associated w. development of ADHD

A

tobacco

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10
Q

which SSRI is most likely to cause weight gain

A

paroxetine

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11
Q

which SSRI has the longest half life

A

fluoxetine

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12
Q

s.e of TCAs

A

anticholinergic: can’t see, pee, spit, shit
antihistamine: drowsy, weight gain, confusion
cardiac: prolonged QT, orthostatic hypotn, tachy

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13
Q

moa for TCAs

A

inhibition of reuptake of norepinephrine and serotonin

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14
Q

pscyh comorbidity mc associated w. illness anxiety d.o

A

gad

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15
Q

which antidepressant is best for neuropathic pain

A

duloxetine

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16
Q

staging of anorexia

A

extreme: BMI < 15
severe: BMI 15-15.99
moderate: BMI 16-16.99
mild: BMI > 17

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17
Q

what personality d.o is mc associated w. bulimia nervosa

A

borderline pd

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18
Q

which SGA is associated w. hyperprolactinemia, amenorrhea, and hypogonadism

A

risperidone

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19
Q

which SGA has lowest probability of hyperprolactinemia, amenorrhea, and hypogonadism

A

aripiprazole

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20
Q

t/f: antipsychotics are most effective for treating negative sx of schizophrenia

A

f!

negative sx don’t respond well to pharm

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21
Q

which pd is associated w. increased risk for suicide

A

borderline pd
antisocial pd

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22
Q

mc adverse effect of lithium

A

nephrogenic diabetes insipidus

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23
Q

most effective tx for severe refractory psychiatric conditions

A

ECT

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24
Q

indications for ECT

A

-refractory/resistant
-need rapid response - ex pregnant/suicidal intent/food refusal
-contraindications to pharm
-previous response to ECT
psychotic features
-catatonia
-persistent suicidal intent

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25
Q

first line tx for cyclothymic d.o

A

lithium

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26
Q

what drug produces the metabolite benzoylecgonine

A

cocaine

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27
Q

criteria used to dx serotonin syndrome

A

hunter

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28
Q

what are the second gen antidepressants

A

SSRIs
SNRIs

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29
Q

what are the atypical antidepressants

A

mirtazapine
bupropion
agomelatine

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30
Q

what are the serotonin modulator antidepressants

A

nefazodone
trazodone

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31
Q

name 2 MAOIs

A

phenelzine
isocarboxazid

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32
Q

name 2 SNRIs

A

duloxetine
venlafaxine

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33
Q

what are the SSRIs

A

citalopram
escitalopram
sertraline
paroxetine
fluoxetine
fluvoxamine

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34
Q

assessment tool for postpartum dpn

A

edinburgh postnatal depression scale

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35
Q

mainstay tx of smoking cessation in pregnant women

A

non pharm: behavioral interventions

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36
Q

what psychiatric condition is mc associated w. panic d.o

A

mdd

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37
Q

avoidance of occupational activities that may involve criticism

A

narcissistic pd

38
Q

self mutilation and increased suicide risk

A

borderline pd

39
Q

2 antipsychotics that are best for pt w. hx of substance abuse

A

risperidone
aripiprazole

40
Q

name 4 first gen antipsychotics

A

haldol
chlorpromazine
perhenazine
thiothixene

41
Q

what distinguishes adjustment d.o from anxiety d.o, mood d.o, and stress d.o

A

adjustment d.o’s are completely situational

42
Q

3 red flags for bipolar d.o w. mixed features

A

agitation
anxiety
irritability

43
Q

best type of therapy for panic d.o

A

CBT:
-teaching the pt about nature of d.o and encouraged to keep mood diary and record of attacks
-breathing techniques/muscle relaxation
-address maladaptive thoughts
-exposure in a graduated manner

44
Q

2 stages of sleep

A

NREM
REM

45
Q

divisions of NREM sleep

A

N1
N2
N3

46
Q

lightest stage of sleep
theta waves

A

N1

47
Q

longest percentage of total sleep is stage

A

N2

48
Q

benzos are associated with increased _ stage of sleep

A

NREM - N2

49
Q

deep sleep/slow wave sleep
delta waves

A

NREM - N3

50
Q

sleep spindles and K complexes

A

NREM - N2

51
Q

in what stage of sleep do parasomnias occur

A

NREM - N3

52
Q

low voltage
sawtooth waves
atonia

A

REM sleep

53
Q

vivid dreaming is associated w. what stage of sleep

A

REM

54
Q

moa for stimulants

A

dopamine and NE reuptake inhibitors

55
Q

moa for atomoxetine

A

selective NE reuptake inhibitor

56
Q

what 2 drugs used for ADHD are alpha 2 adrenergic agonists

A

guanfacine
clonidine

57
Q

functional GI d.o in which ingested food regurgitates into the mouth after meals

A

rumination syndrome

58
Q

management of rumination syndrome

A

diaphragmatic breathing
baclofen

59
Q

what med used for bipolar can cause neural tube defects/spina bifida

A

carbamazepine

60
Q

2 serious s.e of carbamazepine

A

agranulocytosis
SJS/TEN

61
Q

moa for varenicline

A

blocks nicotinic Ach receptors -> decreased craving and withdrawal sx

62
Q

s.e of varenicline

A

n/v
ha
insomnia
appetite changes
abnormal dreams
altered mood
dpn/suicidality
psychosis

63
Q

t/f: ketamine has proven efficacy in decreasing suicidal ideation in suicidal pt’s

A

t!

64
Q

initial tx for somatic sx d.o and illness anxiety d.o

A

regularly scheduled visits w. clinician

65
Q

acute side effects of inhalants

A

lethargy
confusion
HA
sz
CNS dpn
ventricular tachydysrhythmias
myocarditis
sudden cardiac death
pneumonitis
hypoxia

66
Q

4 s.e of chronic inhalant use

A

leukoencephalopathy
myeloneuropathy
sensorimotor peripheral neuropathy
hepatotoxicity

67
Q

risk of carbamazepine toxicity is increased in pt’s who are _ positive

A

HLA-B*1502

68
Q

tx for cannabis withdrawal for patients who are experiencing negative effects in work/school/relationships

A

donabinol
gabapentin
+/- zolpidem if insomnia

69
Q

which antidepressant requires discontinuation x 5 weeks before initiating an MAOI

A

fluoxetine

70
Q

if you have to use pharm for mood stabilization in pregnancy, what med do you choose

A

lamotrigine

71
Q

what mood stabilizer has the highest risk for congenital malformations

A

valproate

72
Q

childhood lifetyle behavior that increases the risk of panic d.o as an adult

A

childhood smoking

73
Q

moa for bupropion

A

DA and NE reuptake inhibitor

74
Q

in order for dx of ASD, what 2 factors must be present

A

-atypical social communication/interaction
AND
-narrow/restricted/repetitive patterns of interests or activities

75
Q

which segment of the brain is responsible for processing fear

A

amygdala

76
Q

hyperactivity in the amygdala is associated with what 2 psychiatric conditions

A

specific phobia
PTSD

77
Q

_ has been associated w. a greater risk of relapse or recurrence of mdd after successful tx

A

childhood maltreatment

78
Q

the risk of recurrence of mdd is greatest w.in _ after treatment

A

the first few months

79
Q

what do you think when you see a patient who is distressed by violent images of himself driving a vehicle over his partner of 5 years - he has never been violent and is very loving

A

OCD

obsessions: recurrent and persistent impulses, thoughts, or images

80
Q

what medication has been shown to aid in weight gain and decrease symptoms of obsesiveness that are commonly associated w. anorexia

A

olanzapine

81
Q

general SSRI dosing for gad

A

half the starting dose that is used for dpn

82
Q

phobia that results from being involved in a specific situation

A

direct conditioning

83
Q

phobia that develops as a result of observing or seeing someone react to a situation

A

vicarious acquisition

84
Q

phobia that develops as a result of hearing stories about something happening

A

informational transmission

85
Q

3 possible findings of schizophrenia on imaging

A

excess synaptic pruning
ventricular enlargement
gray matter loss

86
Q

cyanosis that does not improve w. supplemental O2

A

methemoglobinemia

87
Q

management of methemoglobinemia

A

supportive care
supplemental O2
methylene blue

88
Q

4 PE findings of methemoglobinemia

A

ABG O2 sat normal
pulse ox ~85%
chocolate blood
cyanosis

89
Q

causes of methemoglobinemia

A

amyl nitrite
dapsone
nitrates
antimalarials
-aines
naphthalene (moth balls)

90
Q

what rxn mediates the formation of methemoglobinemia from amyl nitrite exposure

A

oxidation

91
Q

what differentiates sleep terrors from nocturnal panic attacks

A

with sleep terrors:
non REM sleep arousal
associated confusion/unresponsiveness
amnesia for the attack