Rosh Information Flashcards
What antibiotic is best known for causing aplastic anemia?
Chloramphenicol
Differential for pancytopenia
Aplastic anemia Chloramphenicol Leishmania donovani Megaloblastic anemia Paroxysmal nocturnal hemaglobinuria Radiation sickness Transfusion associated GVHD
Most common cause of lower GI bleeding
Diverticulosis
Harsh systolic murmur loudest in early or mid-systole
Mitral regurgitation
2/2 endocarditis, MI and/or trauma
PE: dyspnea, signs of cardiogenic shock
Mid diastolic rumbling murmur
Mitral stenosis
What other syndrome is treated similarly to WPW but does not have a wide QRS or delta wave?
Lown-Ganong-Levine syndrome
Definitive treatment for WPW
Radio frequency ablation
Absolute contraindications of fibrinolytics
Prior ICH Known malignant intracranial neoplasm Know cerebral vascular lesion Ischemic stroke over last 3 months Significant head trauma within 3 months
What alternative fibrinolytic has a relatively high rate of allergic reactions?
Streptokinase
Most common cause of transient aplastic crisis in patients with sickle cell disease?
Parvovirus B19
Most common long term sequelae of myocarditis?
Dilated cardiomyopathy
Most common etiology worldwide for dilated cardiomyopathy
Chagas disease
Most common infectious cause of myocarditis in the US?
Parvovirus B19
What other class of medications may trigger tumor lysis syndrome early in the course of chemotherapy?
Corticosteroids
Findings of a patient with B12 deficiency
Vegan
Fatigue, weakness and peripheral neuropathy
Pallor and glossitis
MCV>100, hypersegmented neutrophils, elevated homocysteine, elevated methylmalonic acid
