[ROQs] Benign Flashcards
What is the 5- and 10-yr LC for a desmoid tumor s/p RT or surgery or both?
- 5-yr: 71%
- 10-yr: 69%
What are the 5-yr survival rates for FAP-associated desmoid tumors according to stage?
I: 95%
II: 100%
III: 89%
IV: 76%
What is the usual RT dose for desmoid tumors?
50-56 Gy
What is the primary treatment modality for a new/recurrent desmoid tumor?
- Active surveillance for at least 1 yr
- Growth can trigger tx
How do you distinguish b/w desmoid tumor and STS?
- Bx
- No specific imaging characteristics of desmoid tumors
- They appear as low-grade sarcomas w/o the nuclear and cytoplasmic features of a malignancy, mitoses, or necrosis
What are the indications for RT for a desmoid tumor?
- Unresectable disease
- Recurrent disease
- R2 resection (residual gross disease)
- or close surgical margins with no possibility of re-resection
Which genetic condition is a/w desmoid tumors?
- FAP
- Desmoid tumors in these pts can form at previous surgical sites, so if they had a colectomy, they could present w/ bowel obstruction and ischemia
What % of paraganglogliomas produce catecholamines?
5%
What is the RT dose for plantar fasciitis fibromatosis?
e-: 30 Gy in 10 fx BID
What is the RT dose for Kaposi sarcoma?
- 8 Gy in 1 fx
- 24 Gy in 12 fx
- 30 Gy in 10-15 fx
What is the cell of origin of Paragangliomas?
- Glomus cells (chemoreceptors along blood vessels)
- Paraganglogliomas aka glomur tumors
What is the long-term control rate for glomus tumors s/p RT?
~90%
What is the classic SRS and conventional doses for glomus tumors?
- SRS: 12-18 Gy (Avg. 15 Gy)
- CF-RT: 45-54 Gy
What % of glomus tumors undergo shrinkage, no growth, and progression post-SRS?
- Shrinkage: ~30%
- No growth: ~60%
- Progression: ~6%
What is the classic appearance of paragangloglioams on MRIs?
Salt and Pepper
What is the BED required for the tx of keloids?
- BED ≥ 60 Gy
What is the first-line treatment for Grave’s ophthalmopathy?
Prednisone: 30 mg/day x 4 weeks
What is the RT dose for Grave’s ophthalmopathy?
20 Gy in 10 fx
What is the formula for various isodose lines for electrons of incident energy Eo?
- 5-4-3-2 rule! (Dmax, D90, D80, Range)
– 4 is actually 3.2
– 3 is actually 2.8
Dx = Eo/x
(X is either 5, 4, 3, or 2 depending on which depth you want!)
What is the relative and absolute risk reduction in HO recurrence w/ RT as compared to NSAIDS (Indomethacin, etc)?
- Absolute: ~1%
- Relative: ~50%
What medication can be used for gynecomastia ppx for men undergoing ADT?
Tamoxifen
What is the RT dose for Duputren’s contracture?
- 30 Gy in 10 fx w/ an 8 week break halfway through RT
- 21 Gy in 7 fx
What is the RT dose for gynecomastia?
- e- to the 85% IDL. Rx include:
– 12 Gy in 3 fx
– 10 Gy in 1 fx - no bolus
What is the staging system for glomus jugulare tumors?
Glomus Jugulare → Glasscock Jackson
