Role of the Nurse Flashcards
Are generic and trade name drugs identical?
No. Fillers and interactions may differ.
What are the four phases for therapeutic drug review?
1) Preclinical investigation
2) Clinical investigation
3) Review of the NDA
4) Postmarketing surveillance
What is the average time to get new drugs on the market?
11 years
What is withdrawal?
Physical discomfort felt by an individual when substance is no longer available.
What did the controlled substances act of 1970 implement?
Schedules, federal oversight. Every dose must be accounted for.
Other drugs with abuse potential?
Nicotine, alcohol, caffeine.
How many levels are there for drug abuse potential? What is the least likely and most likely abuse category?
Five levels of abuse potential. Class 1 is most likely to abuse and class 5 is least likely to abuse.
1 - Abuse potential (highest), Physical dependency (high), psychological dependence (high)
2 - Abuse potential (high), physical dependence (high), psychological dependence (high)
3 - abuse potential (moderate), physical dependence (moderate), psychological dependence (high)
4 - abuse potential (lower), physical dependence (lower), psychological dependence (lower)
5 - abuse potential (lowest), physical dependence (lowest), psychological dependence (lowest)
What are some examples of class 1 drugs?
Heroin, Marijuana, ecstasy
What are some examples of class 2 drugs?
Hydromorphone, methadone, oxycodone, codeine, morphine, meperidine, oxycontin.
What are some examples of class 3 drugs?
<15 mg hydrocodone, ketamine, anabolic steroids, benzphetamine.
What are some examples of class 4 drugs?
Alpazolam, diazepam, clonazepam.
What are some examples of class 5 drugs?
Cough preparations <200 mg codeine
What is a teratogen?
Substance that has the potential to cause a defect in an unborn child during pregnancy.
What are the categories for classifying pregnancy risk? Which is the safest and most dangerous.
A, B, C, D, and X
Category A is the safest
Category X poses the most danger.
Describe pregnancy category A?
No risk to fetus.