Role of Radiation Flashcards
What aspects of care of head and neck cancer patients is radiology required for?
Diagnosis
Staging
Pre-radiotherapy
Checking treatment response/recurrence
Checking for post-op complications
Dental rehabilitation
What imaging is used in diagnosis of cancer?
Oral cavity- exophytic soft tissue mass or non-healing socket
-> Take OPT to look for bone involvement
If neck lump- ultrasound
What are the radiological signs that may indicate a cancer diagnosis?
Moth eaten bone- areas of ill-defined radiolucency and sclerosis
Pathological fractures
Non-healing sockets
Floating teeth
Unusual perio bone loss- marked around one tooth
Spiculated periosteal reaction
Widening of PDL- with no occlusal trauma
Loss of bony outline for anatomical structures- IDC, walls of antrum
Thinning of cortico-endosteal margin
Atypical aggressive root resorption
What are the other causes of moth-eaten bone?
MRONJ
ORN
Osteomyelitis
What are the common metastases of Adenoid Cystic Carcinoma?
Ribs
Spine
Lungs
What are the signs on ultrasound of cancer in neck lumps?
- LNs- appearing round (should be kidney shaped/rugby ball shaped)
- Enlargement in short axis (if over 10mm- concerning)
- Conglomerate nodes- LNs fuse together
- Necrosis of nodes
- Increased vascularity- normally through hilum, if increased/avascular it is concerning or hilum is lost
- Internal calcification- only present in metastatic SSC/papillary carcinoma of thyroid
- Extracapsular spread- outline of node disappears and extends to involve other tissues like BVs
What else must we consider when looking at neck lumps?
Are they unilateral/bilateral
Are they single or mutliple
What level of neck are they on
What are the levels of the neck?
- Level 1- submental/mandibular region
- Level 2-4- cervical chain
- Level 5 posterior triangle
- Level 6 midline
How does a normal node appear on ultrasound?
- Kidney bean shaped
- Hilum appears white
- Black capsule
What is the difference between FNA and Core biopsy?
FNA- cells for cytopathology
Core biopsy- histopathological sample
What staging is used for tumours?
TNM8
-> different between oropharyngeal, oral cavity, maxillary sinus
-> We consider HPV status and depth of invasion
What is required in order to come to a TNM staging?
Requires imaging in 3D of brain, pelvis, chest and abdomen with large field of view to look for metastases
-> CT
-> MRI
TNM brief description:
T 1-4 (smallest to advanced)
N 0-3
- No nodes up to bilateral
- Size
- Extracapsular spread
Metastases- distant metastases from original site
CT vs MRI:
CT
-> quick
-> good for soft tissue and bone
-> iodinated contrast must be given (enhances tumour)
MRI
-> no radiation
-> Good for soft tissue, marrow involvement, perineurial spread
What must be tested before iodinated contrast can be given for CT?
Blood test- eGFR, creatinine
-> check kidney function