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Internal Medicine > Roi Loan Lipid > Flashcards

Roi Loan Lipid Flashcards

0
Q

TG ngoai sinh?

A

Chylomicron: ruot non-sau an- mo ngoai sinh( nhieu TG it Chole) den gan va mo khac.
Chylo remnant: LDL-receptor o gan,
LPL phong TG

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1
Q

Cau truc lipoprotein?! Bao nhieu loai, xep theo thu tu nao?!

A

Loi: TG va cholesterol ester
Vo: phospholid va apolipoprotein
5 loai:
Chylomicron-VLDL-IDL-LDL-HDL: giam duong kinh, tang ti trong

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2
Q

TG noi sinh?

A

TG - acid beo tu do trong mau.
VLDL: gan –) IDL: gan+LPL–) LPL dua choles den mo la chu yeu
HDL: gan+ruot: cholesterol ve gan

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3
Q

Nong do LDL?

A

LDL-receptor
HMG-CoA reductase
Chu trinh gan ruot: mat- doan cuoi hoi trang

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4
Q

RL lipid mau la gi?

A

Tang Choles/TG

Giam HDL

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5
Q

Nguyen nhan nguyen phat?

A

4 nn: da gen, lipid gia dinh, chole gia dinh, TG gia dinh

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6
Q

NN thu phat?

A

Suy giap, DTD, cushing, than hu, than man/giai doan cuoi, gan u mat, gan tac nghen, ruou, thuoc( thiazid, beta block, GC, estrogen tong hop)

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7
Q

NCEP-ATP 3: lich

A

Tu 20 tuoi, 5 nam mot lan

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8
Q

B1+ khoang cua BiLan lipid

A 
Bilan 12h doi
TG: 149 150-199 200-499 500
Chole TP : 199 200-239 240
HDL 40 60
LDL 99 100-129 130-159 160-189 190
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9
Q

B2:

A

BMV: tien can NMCT, dau that nguc khong on dinh, thu thuat mach vanh hay co bang chung thieu mau co tim trrnls
Tuog duong
DM ngoai bien, phinh dm chu bung, hep dmcanh trieu chung: thieu mau nao thoang qua, stroke do hep hon 50%
Teuduong
)=2 ytnc va Fra 10 nam )20%

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10
Q

YTnC tim mach chinh B3

A 
Thuoc la
Huyet ap
HDL (40
Gia dinh nam (55 nu (65
Tuoi nam)45 nu )55
HDL)60: tru di mot ytnc chinh
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11
Q

B4

A

)=2 ytnc chinh khong BMV hay tiong duong

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12
Q

Nguy co rat cao?

A 
BMV+
- nhieu ytnc db DTD
- ytnc nanng kho kiem soat: thuoc la
HC chuyen hia
Hc vanh cap
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13
Q

B5

A 
LDL muc tieu
Rat cao:(70
Cao(100 BMV va tuog duong 
Cao trung binj ( 130 2ytncc va Fra)20%
Trung vinh (130 2ytncc ca Fra10-20
Thap (160 0-1ytncc
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14
Q

B6

A

Dieu tri
Cao: loi song+ thuoc
Other: loi song–) thuoc

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15
Q

Loi song?

A

Che do an: thuco + khau phan
Tang the luc
Can nang ly tuing

16
Q

Theo doi

A

Loi song 3 thang kiem tra lai, ko muc tieu thi thuoc

Thuoc : 6-8 tuan trong 4-6 thang

17
Q

Huog dan:

A

If TG)500: Niacin/ fibrat
Not
LDL ve muc tieu roi den TG va HDL

18
Q

B8: HC chuyen hoa

A 
Bung: nam )90 nu ) 80
HA 135/80
FBG: 110mg/dl
HDL (40 nam (50 nu
TG)150
19
Q

B9 dat duoc LDL mong muon, dieu tri TG

A

)150 loi song
)200 non-HDL: muc tieu LDL +30
Tang lieu statin
Phoi hop fibat/ niacin

20
Q

HDL thap?

A

TG)200: theo nonHDL

(200: bn co BMV hay tuong duong thi dub Niacin va Fibrat

21
Q

Cac nhom thuoc

A 
Statin : dau tay
Niacin acid Nicitinic
Fibrat dan xuat acid fibric
Chat gan acid mat
Chat uc che hap thu cholesterool
Dau ca
22
Q

Nu 55 tuoi ko tc benh mach vanh den kham va tu van suc khoe. HA135/85 ko thuoc la, ko DTD, man kinh 3 nam BMI 24. Chole TP 240 HDL 55 TG 85 LDL 180. Gia dinh khong mac benh mach vanh som
Muc tieu LDL
Sau tap the duc 3 thang ko cai thien
If dau cach hoi khi di bo

A

Jb

23
Q

Nam 40 tuoi ko tien can noi khoa, cha NMCT 45 tuoi. Thuoc la 23 goi.nam. LDL 170 HDL 35 TG 140 xn khac binh thuong
Muc tieu LDL
Dung thuoc ko?! Thuoc gi?

A

Ndfn

24
Q

Nu 65 tuoi beo phi, DTD THA. Chole cao nhung dang trong che do chole thap duoc 6 thang. Nghiem phap gang suc binh thuong nam ngoai truoc khi phau thiat thay khop goi va ko co trieu chung tim mqch. LDL 130 HDL 30 TG 300 HbA1C 6,5
Ldl muc tieu
Dieu trii
Xet nghiem them gi

A

Cvv

25
Q

Nhom statin

A

Artovas, ruvast tac dung ngan, uong dem
Giam tong choles; tang thu the LDL, giam tong VLDL
Tang men gan, dau co khop, kho tieu

26
Q

Nhom gan acid mat

A

Chole-
Tang LDL
Tang bai tiet mat; tang thu the LDL
Tang TG, day hoi, tao bon

27
Q

Niacin

A

Tang LDL, gian HDL, tang TG
Giam tong VLDL
Tang men gan , tang duong huyet, tang ure huyet, do da, tao bon

28
Q

Fibrat

A

Tang TG, tang phan thua
Tang hoat LPL, giam tong VLDL
Tang men gan, soi mat, dau co, kho tieu

29
Q

Dau ca

A

Tang TG cao
Giam Chylomicron, giam VLDL
Tieu chay, hoi tho mui ca, kho tieu

30
Q

Uc che hap thu choolesterol

A

Tang LDL
Giam hap thu choles
Tang men gan

Internal Medicine (3 decks)

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