Roi Loan Lipid

Question 0

TG ngoai sinh?

Answer 0

Chylomicron: ruot non-sau an- mo ngoai sinh( nhieu TG it Chole) den gan va mo khac.
Chylo remnant: LDL-receptor o gan,
LPL phong TG

Question 1

Cau truc lipoprotein?! Bao nhieu loai, xep theo thu tu nao?!

Answer 1

Loi: TG va cholesterol ester
Vo: phospholid va apolipoprotein
5 loai:
Chylomicron-VLDL-IDL-LDL-HDL: giam duong kinh, tang ti trong

Question 2

TG noi sinh?

Answer 2

TG - acid beo tu do trong mau.
VLDL: gan –) IDL: gan+LPL–) LPL dua choles den mo la chu yeu
HDL: gan+ruot: cholesterol ve gan

Question 3

Nong do LDL?

Answer 3

LDL-receptor
HMG-CoA reductase
Chu trinh gan ruot: mat- doan cuoi hoi trang

Question 4

RL lipid mau la gi?

Answer 4

Tang Choles/TG

Giam HDL

Question 5

Nguyen nhan nguyen phat?

Answer 5

4 nn: da gen, lipid gia dinh, chole gia dinh, TG gia dinh

Question 6

NN thu phat?

Answer 6

Suy giap, DTD, cushing, than hu, than man/giai doan cuoi, gan u mat, gan tac nghen, ruou, thuoc( thiazid, beta block, GC, estrogen tong hop)

Question 7

NCEP-ATP 3: lich

Answer 7

Tu 20 tuoi, 5 nam mot lan

Question 8

B1+ khoang cua BiLan lipid

Answer 8

Bilan 12h doi
TG: 149 150-199 200-499 500
Chole TP : 199 200-239 240
HDL 40 60
LDL 99 100-129 130-159 160-189 190

Question 9

B2:

Answer 9

BMV: tien can NMCT, dau that nguc khong on dinh, thu thuat mach vanh hay co bang chung thieu mau co tim trrnls
Tuog duong
DM ngoai bien, phinh dm chu bung, hep dmcanh trieu chung: thieu mau nao thoang qua, stroke do hep hon 50%
Teuduong
)=2 ytnc va Fra 10 nam )20%

Question 10

YTnC tim mach chinh B3

Answer 10

Thuoc la
Huyet ap
HDL (40
Gia dinh nam (55 nu (65
Tuoi nam)45 nu )55
HDL)60: tru di mot ytnc chinh

Question 11

B4

Answer 11

)=2 ytnc chinh khong BMV hay tiong duong

Question 12

Nguy co rat cao?

Answer 12

BMV+
- nhieu ytnc db DTD
- ytnc nanng kho kiem soat: thuoc la
HC chuyen hia
Hc vanh cap

Question 13

B5

Answer 13

LDL muc tieu
Rat cao:(70
Cao(100 BMV va tuog duong 
Cao trung binj ( 130 2ytncc va Fra)20%
Trung vinh (130 2ytncc ca Fra10-20
Thap (160 0-1ytncc

Question 14

B6

Answer 14

Dieu tri
Cao: loi song+ thuoc
Other: loi song–) thuoc

Question 15

Loi song?

Answer 15

Che do an: thuco + khau phan
Tang the luc
Can nang ly tuing

Question 16

Theo doi

Answer 16

Loi song 3 thang kiem tra lai, ko muc tieu thi thuoc

Thuoc : 6-8 tuan trong 4-6 thang

Question 17

Huog dan:

Answer 17

If TG)500: Niacin/ fibrat
Not
LDL ve muc tieu roi den TG va HDL

Question 18

B8: HC chuyen hoa

Answer 18

Bung: nam )90 nu ) 80
HA 135/80
FBG: 110mg/dl
HDL (40 nam (50 nu
TG)150

Question 19

B9 dat duoc LDL mong muon, dieu tri TG

Answer 19

)150 loi song
)200 non-HDL: muc tieu LDL +30
Tang lieu statin
Phoi hop fibat/ niacin

Question 20

HDL thap?

Answer 20

TG)200: theo nonHDL

(200: bn co BMV hay tuong duong thi dub Niacin va Fibrat

Question 21

Cac nhom thuoc

Answer 21

Statin : dau tay
Niacin acid Nicitinic
Fibrat dan xuat acid fibric
Chat gan acid mat
Chat uc che hap thu cholesterool
Dau ca

Question 22

Nu 55 tuoi ko tc benh mach vanh den kham va tu van suc khoe. HA135/85 ko thuoc la, ko DTD, man kinh 3 nam BMI 24. Chole TP 240 HDL 55 TG 85 LDL 180. Gia dinh khong mac benh mach vanh som
Muc tieu LDL
Sau tap the duc 3 thang ko cai thien
If dau cach hoi khi di bo

Answer 22

Jb

Question 23

Nam 40 tuoi ko tien can noi khoa, cha NMCT 45 tuoi. Thuoc la 23 goi.nam. LDL 170 HDL 35 TG 140 xn khac binh thuong
Muc tieu LDL
Dung thuoc ko?! Thuoc gi?

Answer 23

Ndfn

Question 24

Nu 65 tuoi beo phi, DTD THA. Chole cao nhung dang trong che do chole thap duoc 6 thang. Nghiem phap gang suc binh thuong nam ngoai truoc khi phau thiat thay khop goi va ko co trieu chung tim mqch. LDL 130 HDL 30 TG 300 HbA1C 6,5 Ldl muc tieu Dieu trii Xet nghiem them gi

Answer 24

Cvv

Question 25

Nhom statin

Answer 25

Artovas, ruvast tac dung ngan, uong dem Giam tong choles; tang thu the LDL, giam tong VLDL Tang men gan, dau co khop, kho tieu

Question 26

Nhom gan acid mat

Answer 26

Chole- Tang LDL Tang bai tiet mat; tang thu the LDL Tang TG, day hoi, tao bon

Question 27

Niacin

Answer 27

Tang LDL, gian HDL, tang TG Giam tong VLDL Tang men gan , tang duong huyet, tang ure huyet, do da, tao bon

Question 28

Fibrat

Answer 28

Tang TG, tang phan thua Tang hoat LPL, giam tong VLDL Tang men gan, soi mat, dau co, kho tieu

Question 29

Dau ca

Answer 29

Tang TG cao Giam Chylomicron, giam VLDL Tieu chay, hoi tho mui ca, kho tieu

Question 30

Uc che hap thu choolesterol

Answer 30

Tang LDL Giam hap thu choles Tang men gan