RNA VIRUSES Flashcards

1
Q

Diagnosis of ROTA VIRUS is by-

A

VP6 antigen detection by ELISA in stool

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2
Q

Vaccine for rota virus

A

Vp4 and vp7 recombinant vaccine- orally

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3
Q

S/e of rota virus vaccine

A

Intussuseption

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4
Q

Viruses that cause infantile gastroenteritis are_

A

1) rota virus - most common cause
2) Calci virus → Norovirus(Norwalk) &sapo virus
3) Astro virus
4 toga virus
5) Adeno 40,41(DNA viruses)

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5
Q

Types A, B &c of influenza virus are based on _

A

Nucleo capsid

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6
Q

Strain of mumps vaccine

A

Jerry Lynn strain.

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7
Q

Incubation period for mumps

A

7-23 days

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8
Q

Parainfluenza type 1 and 2 causes

A

Croup(laryngatracheobronchitis)

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9
Q

Para influenza type 3 causes (most prevalent serotyne)

A

Pneumonia

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10
Q

Most common complication of measles virus is

A

Otitis media

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11
Q

Measles diarrhea and malnutrition causes what deficiency

A

Vitamin A

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12
Q

Cns complications of measles within 1 year is

A

Post measles encephalitis - autoimmune - and most common

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13
Q

Cns complication of measles in 1-5 years is

A

Mlbe (measles inclusion body encephalitis)

D/t viral reactivation

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14
Q

Cns complication of measles in 5-25 years is

A

Sspe (subacute sclerosing panencephalitis)

viral reactivation

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15
Q

Measles diagnosis from the days of onset of rash _

A

1-7 days → PCR of nasopharyngeal swab

7-28 days → ab detection by ELISA

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16
Q

Measles vaccine strain

A

Edmonton Zagreb strain

17
Q

Genotype of measles virus

A

B3 is mc world wide

In India → d8

18
Q

Rubella vaccine -

A

RA 27/3

19
Q

Rubella causes

A

Exanthematous lesions and keratitis

20
Q

Bronchiolitis is caused by

A

Rsv>hmpv

21
Q

Picarno Virus causing acute hemorrhagic conjunctivitis.

A

Coxsackie A24

Entero 70

22
Q

Picarno virus causing aseptic meningitis is /are

A

Entero 70,71

23
Q

Picarno Virus causing encephalitis and exanthem is

A

Entero 71

24
Q

Picarno Virus causing hand, foot and mouth disease are

A

Coxsackie A 16

Entero 71

25
Q

Picarno Virus causing herpangina are

A

Coxsackie A 1-10, 16, 22

26
Q

Coxsackie B 1-6 viruses cause?

A

Pleurodynia/bornholm disease→ devil’s grip
Myocarditis/pericarditis
Aseptic meningitis
Sudden death.

27
Q

Corona SARS 2003 outbreak strain

A

HCov oc23

28
Q

Most sensitive investigation (ante-mortem) for Rabies Virus is

A

Immuno peroxidase and immunofluorescence using antirabies monoclonal ab

29
Q

Other investigations for Rabies are

A

Ab in Csf

Pcr in brain tissue

30
Q

Diagnosis for dengue

A

Within 5 days → NS1 antigen detection

After 5 days → ig M ELISA (IOC)

31
Q

Dengue Vaccine

A

Recombinant vaccine type 1-4

32
Q

Investigation for chikungunya

A

Ig M ELISA

33
Q

Ioc for zika Virus

A

Ig M capture ELISA

34
Q

Investigation forJE virus and vaccination _

A

Ab detection

VACCINE - SA 14-14-2

35
Q

Vaccine for yellow fever

A

17D vaccine