RNA VIRUSES

Question 1

Diagnosis of ROTA VIRUS is by-

Answer 1

VP6 antigen detection by ELISA in stool

Question 2

Vaccine for rota virus

Answer 2

Vp4 and vp7 recombinant vaccine- orally

Question 3

S/e of rota virus vaccine

Answer 3

Intussuseption

Question 4

Viruses that cause infantile gastroenteritis are_

Answer 4

1) rota virus - most common cause
2) Calci virus → Norovirus(Norwalk) &sapo virus
3) Astro virus
4 toga virus
5) Adeno 40,41(DNA viruses)

Question 5

Types A, B &c of influenza virus are based on _

Answer 5

Nucleo capsid

Question 6

Strain of mumps vaccine

Answer 6

Jerry Lynn strain.

Question 7

Incubation period for mumps

Answer 7

7-23 days

Question 8

Parainfluenza type 1 and 2 causes

Answer 8

Croup(laryngatracheobronchitis)

Question 9

Para influenza type 3 causes (most prevalent serotyne)

Answer 9

Pneumonia

Question 10

Most common complication of measles virus is

Answer 10

Otitis media

Question 11

Measles diarrhea and malnutrition causes what deficiency

Answer 11

Vitamin A

Question 12

Cns complications of measles within 1 year is

Answer 12

Post measles encephalitis - autoimmune - and most common

Question 13

Cns complication of measles in 1-5 years is

Answer 13

Mlbe (measles inclusion body encephalitis)

D/t viral reactivation

Question 14

Cns complication of measles in 5-25 years is

Answer 14

Sspe (subacute sclerosing panencephalitis)

viral reactivation

Question 15

Measles diagnosis from the days of onset of rash _

Answer 15

1-7 days → PCR of nasopharyngeal swab

7-28 days → ab detection by ELISA

Question 16

Measles vaccine strain

Answer 16

Edmonton Zagreb strain

Question 17

Genotype of measles virus

Answer 17

B3 is mc world wide

In India → d8

Question 18

Rubella vaccine -

Answer 18

RA 27/3

Question 19

Rubella causes

Answer 19

Exanthematous lesions and keratitis

Question 20

Bronchiolitis is caused by

Answer 20

Rsv>hmpv

Question 21

Picarno Virus causing acute hemorrhagic conjunctivitis.

Answer 21

Coxsackie A24

Entero 70

Question 22

Picarno virus causing aseptic meningitis is /are

Answer 22

Entero 70,71

Question 23

Picarno Virus causing encephalitis and exanthem is

Answer 23

Entero 71

Question 24

Picarno Virus causing hand, foot and mouth disease are

Answer 24

Coxsackie A 16

Entero 71

Question 25

Picarno Virus causing herpangina are

Answer 25

Coxsackie A 1-10, 16, 22

Question 26

Coxsackie B 1-6 viruses cause?

Answer 26

Pleurodynia/bornholm disease→ devil’s grip
Myocarditis/pericarditis
Aseptic meningitis
Sudden death.

Question 27

Corona SARS 2003 outbreak strain

Answer 27

HCov oc23

Question 28

Most sensitive investigation (ante-mortem) for Rabies Virus is

Answer 28

Immuno peroxidase and immunofluorescence using antirabies monoclonal ab

Question 29

Other investigations for Rabies are

Answer 29

Ab in Csf

Pcr in brain tissue

Question 30

Diagnosis for dengue

Answer 30

Within 5 days → NS1 antigen detection

After 5 days → ig M ELISA (IOC)

Question 31

Dengue Vaccine

Answer 31

Recombinant vaccine type 1-4

Question 32

Investigation for chikungunya

Answer 32

Ig M ELISA

Question 33

Ioc for zika Virus

Answer 33

Ig M capture ELISA

Question 34

Investigation forJE virus and vaccination _

Answer 34

Ab detection

VACCINE - SA 14-14-2

Question 35

Vaccine for yellow fever

Answer 35

17D vaccine