RNA virus

Question 1

Vilka är Baltimores 7 olika virusgrupper?

Answer 1

Grupp 1: dsDNA
Grupp 2: ssDNA
Grupp 3: dsRNA
Grupp 4: +ssRNA
Grupp 5: -ssRNA
Grupp 6: rt +ssRNA
Grupp 7: rtDNA

Question 2

Reoviridae, rotavirus

Answer 2

dsRNA, segmenterat, naket (18kb)

typ A-> gastroenterit

Question 3

Coronaviridae

Answer 3

+ssRNA, icke-segmenterat, helikal nucleocapsid, spike protein (30kb)

Question 4

Picornavirus

Answer 4

+ssRNA, icke-segmenterat, naket (7-8kb)

Enterovirus

Question 5

Flavivirus

Answer 5

+ssRNA, icke-segmenterat, ikosahedral kapsid, hölje (11kb)
Gula febern, dengue virus, japansk encefalit virus, West Nile virus, Zika virus, Tick-borne encephalitis virus, Heptatit C virus

Question 6

Togavirus

Answer 6

+ssRNA, ikosahedral kapsid, hölje (8-12kb)

Sindvis virus och rubella virus

Question 7

Astroviridae

Answer 7

\+ssRNA 
Humant astrovirus (diarré)

Question 8

Caliciviridae

Answer 8

+ssRNA

Norovirus, sapovirus (vinterkräksjuka)

Question 9

Hepeviridae

Answer 9

+ssRNA

Hepatit E virus

Question 10

Alla -ssRNA virus…

Answer 10

1. Har helikal kapsidsymmetri och hölje
2. Infekterar celler genom fusion med plasmamembranet (ej influensa)
3. Måste innehålla RNA-polymeras
4. Replikeras i cytoplasman (ej influensa)
5. Knoppas av i cellens plasmamembran

Question 11

Mononegavirales

Answer 11

-ssRNA, icke-segmenterat
Rhabdoviridae - rabies
Filoviridae - Ebola, marburg
Paramyxoviridae - Mässing, RSV

Question 12

Paramyxoviridae, Morbillivirus

Answer 12

-ssRNA, icke-segmenterat (16kb)
Mässling
Smittar via luftvägar
Vaccination med levande attenuerat vaccin

Question 13

Paramyxoviridae, Respiratory syncytial virus (RSV)

Answer 13

-ssRNA, icke-segmenterat (15kb)

Question 14

Arenaviridae

Answer 14

-ssRNA, segmenterat

Hemorrhagic fever

Question 15

Bunyaviridae

Answer 15

-ssRNA, segmenterat

Hantavirus, phlebovirus

Question 16

Orthomyxoviridae

Answer 16

-ssRNA, segmenterat (14kb)

Influensavirus A, B, C