RMP

Question 1

What is RMP?

Answer 1

The difference in electrical charge across the membrane at rest

Question 2

What ions are involved?

Answer 2

Na+, K+, Cl-

Question 3

What are the three factors that mean electrical charge is distributed unevenly?

Answer 3

1) Permiability
2) Concentration gradient
3) Electrical gradient

Question 4

Outline what is meant by permiability

Answer 4

Proteins sitting in the membrane allow ions to pass through. Gates block the flow of ions, changes in voltage opens the gates:

• Sets RMP
• Generates AP

Question 5

Outline what is meant by concentration gradient

Answer 5

Ion pumps maintain concentration gradient, the Na+ K pump exchanges 3 internal Na+ ions for 2 external K+ ions due to ATP
Sodium in, potassium out

Question 6

Outline what is meant by electrical gradient

Answer 6

Ions are electrically charged, so opposites attract.

Glial cells are selectively permeable to K+ at rest, they have high K+ inside which diffuses the CG out of the cell.

Question 7

What is the nerst equation?

Answer 7

A way to figure out the equilibrium potential