Risks Flashcards
Target EBWL of lap.gastric banding
TBW?
35-40% EWL
TBW 20-25
> 40% regain their weight
Target EBWL of Sleeve gastrectomy
55-70%
Target EBWL of RYGB
60-75% EXCESS body weight.
Better if BMI<50
long term 20% regain most of their weight
Target EBWL of BPD/DS
70-80%
Gastric band cons 4
Erosion,
slip/prolapse,
explant (removal) rate 40%,
failure to lose 25% excess body weight |
Sleeve gastrectomy complications 3
20-30% NEW GERD
Leaks
stricture/ stenosis
unfavorable aspects of RYGB 5
Few revision options Marginal ulcers 20% Internal hernias Long term micronutrient deficiencies Anemia
Favorable aspects biliopancreatic diversion with duodenal switch 4
very strong metabolic effects
Durable weight loss
Effective for patients with very high BMI
Can be used as second stage after sleeve gastrectomy
Cons of duodenal switch 4
- Malabsorptive/-highest rate micronutrient deficiencies
- GERD
- 3-5% protein-calorie malnutrition
- duodenal dissection
ASMBS impact of min 5% weight loss
T2D
dyslipidemia, HTN,
NAFLD
low testosterone, PCOS
( AOS/reactive airways) 7-8%
urinary stress incontinence,
ASMBS impact of min 10% weight loss 6
3 metabolic, 2 fat mass, 1 psych
MetS,
prediabetes,
NASH,
OA,
GERD,
depression
Relative CIs for bariatric surgery
- Hx substance abuse/eating disorder, smoking
- Hx psychiatric hospitalization in last year, suicidal ideation, major psych issue
- Patients too ill or high risk
- Women wanting to conceive within 12 mos.
Who has increased risk for weight loss surgery?
mostly common sense
Old fat smoking diabetic men (BMI>50,age>60)
Cardiac Hx:HTN, CAD with prior MI/PTCA, unstable angina, CHF
Pulmonary hx:COPD,OSA,pulmHTN low baseline O2
Hx/Fhx thromboembolic disease
End organ failure/transplant, non-ambulatory, ECOG<2
Pre-op weight loss benefit 3
Decreased OR time
Smaller liver size
reduced peri-operative complications
Gastric bypass OR time/hospital stay/recovery
Gastric sleeve OR/hospital stay/recovery
1hr40min/1-3 days/4-6 weeks
1 hr/ 1-2 days/2-3 weeks
Lap adjustable Gastric Banding - approved for what BMI
BMI 30-35
Sleeve gastrectomy- how much of stomach removed, what is volume remaining, how does it work??
75-80% removed,
60-100 ml left
Removes greater curve, greatly reducing Ghrelin production
What is involved in a Biliopancreatic diversion with a Duodenal switch?
( BPD-DS)
sleeve gastrectomy+>80%small bowel bypassed, absorptive channel reduced to 75-150 cm
What is a Loop duodenal switch ( SADIS or SIPS)
sleeve gastrectomy and about 50% bypassed small bowel, absorptive channel remaining 300 cm
EWL for BPD-DS at 10 years
70-80%
EWL with loop duodenal switch
* EBW is the amount of body weight you have in excess of your target weight
70-80%
Which non-obesity and obesity related medical conditions is sleeve gastrectomy best for 4
Kidney stones
Hx or pending organ transplant
Higher pre=op cardio-pulmonary risk
Severe baseline nutritional deficiencies
Which procedure is best if patient has GERD?
RNY
best procedures if BMI>50 or Type II DM
RNY or BPD , SIPS**
How does post-op rhabdomyolysis present? 2 labs 2 symptoms
low urine output, dark urine, elevated CPK and myoglobin in urine
How do leaks present post-op? When, where, how? What tests to order? detailed slide
- Early, in first 2 weeks
- at GJ anastamosis or proximal staple line
- tachycardia,worsening abd/left chest pain, leukocytosis,fever,oliguria, LEFT PLEURAL EFFUSION
- Tests - UGI study, CT, amylase
About post-op bleeding - where, treatment/investigation
Luminal (hematesis,BRBPR) or intraperitoneal ( bloody drain output)
Resuscitate, hold anti-coag, correct coags and transfurse PRN
EGD PRN if intraluminal bleeding
Usually settle without intervention
Marginal ulcers after RNY 1-7(20%). What triggers them 6 how to treat?
NSAIDS caffeine ETOH Diabetes Smoking systemic steroids treat- Sucralfate, PPI, improve nutrition, stop smoking
Post-op DVT/PE - how common, presentation, investigation
1% fatal PE
tachycardia, O2 desat., SOB, chest pain
do CT angio
Anastomotic stricture/stenosis - up to 27% after GBP
Symptoms 3? Treatment?
- dysphagia, solid food intolerance, excessive OR poor weight loss
- Treatment - balloon dilatation
Internal hernias occur late, 1-2 years post-op. How to diagnose?
Abdominal pain, N/V, non-specific symptoms.
Order KUB/CT scan - “swirl sign”
up to 50% need surgical exploration
Lap. gastric banding “erosion” symptoms 3
No symptoms
“Loss of restriction”
Pain/inflammation or infection at port site
Post-op vitamins 5
MVI: 2 daily with 18-27 mg IRON Calcium citrate 1200-1500 mg vitamin D 3000 IU (goal >30) vitamin B12 300-500 mcg po/SL QD/ 1000 mcg SC qmonth 500-1000 mcg intranasal weekly
(Folate 400-1000 mcg QD
CU 1-2 mg/day
check Cu,Zn,Se
Insufficient weight loss = losing less than 40-50 % EBW. Post- surgical reasons 3?
Large or dilated gastric pouch
Dilated G-J anastomosis
Gastro-gastric fistulas
Excessive weight loss/Protein malnutrition.
Differential Dx:4 surgical complications + 1 psych
Anorexia nervosa or bulemia Surgical: Vomitting due to Anastomotic stenosis Vomitting due to ulcers Intestinal bacterial overgrowth Too much intestine bypassed.
Biliary complications - gall stone formation more common with bypass surgery. Rate of cholecystectomy required, preventative treatment
8% need surgery, even though 36% develop stones
Can give ursodeoxycholic acid for 6 months but compliance can be poor
Refeeding syndrome presentation - 3 lab and 4 symptoms
Hypo Mag, K , PO4
Cardiac arrythmias, weakness, seizures, coma
Dumping syndrome=rapid emptying of hypertonic carb load into small bowel. <1hour - Distention of small bowel Late 1-3 hours-Causes rapid glucose absorption, hyperglycemia, exaggerated insulin release and hypoglycemia.
Symptoms
Abdominal pain, cramping, flushing, palpitations, diaphoresis, tachycardia, hypotension, tremors, confusion, seizures
Most common deficiency after GBP, and why 3
Iron deficiency anemia 1.decreased acid secretion in gastric pouch 2. Chronic use of H2 blockers and PPIs 3. Decreased intake of iron rich foods Monitor 2x/year
Vitamin B12 deficiency 26-70% - reasons 3 and symptoms/abnormalities 5
- Achlorhydria
- Decreased consumption
- Less intrinsic factor secretion
Neurologic symptoms,
megaloblastic anemia ( also found in COPPER deficiency), low platelets, low WBC,
glossitis
Folic acid deficiency - causes,supplementation dose
Achlorhydria
Associated with Vit B12 deficiency and decreased consumption.
1 mg/day
Thiamine deficiency after bariatric surgery causes 3
symptoms 5
dose
Increased loss - excessive post-op vomitting
Reduced absorption -due to decreased acid and duodenal exclusion in gastric bypass.
Sx: lower extremity weakness/neuropathy/nystagmus/diploplia/Wernicke’s encephalopathy.
Tx:If neurological symptoms, 100 mg/d IV for 7-14 days , then 10 mg PO QD
Vit A def 52-69% def after BPD, 10% after RYGB-sx?
visual difficulties at night
Sx of Zinc def 5
*can cause impaired Folic Acid absorption
Mouth ulcers
dry scaly skin
acne
Hair loss
hypogonadism
Sx of Mg deficiency 5
fatigue dizziness weakness muscle twitches cramps
Selenium deficiency 3
fatigue
hypothyroidism
cardiomyopathy (Keshan disease)
Symptoms of protein malnutrition 3
edema/anasarca
hair loss
muscle wasting
*check albumin/pre-albumin, lowest about 1-2 years after surgery
Surgery related hormone changes that promote satiety 3
- GLP-1 enhanced basally and post-prandially with bypass
- Ghrelin is reduced in bypass and sleeve
- PYY is elevated post-prandially in bypass and sleeve
Managing pre-op diabetes meds 3
- Reduce long acting insulin by 60% initially during the 1-2 wk preop liquid diet
- Use higher blood glucose levels for further titrations 140-180
- if not on insulin, consider dropping hypoglycemics
Meds to consider changing for malabsorptive patients 3
- Extended release formulations
- Coumadin
- OCPs
Post-op labs for gastric bypass 14
CBC glucose LFT lipids iron studies ferritin vitamin B12 (or elevated MMA >0.4) Vit D25 metabolic panel (lytes) albumin pre-albumin RBC-folate intact PTH Calcium Optional thiamine, vitaminA , Zn, copper/ceruloplasmin
Annual BMD until stable
Adolescent weight loss surgery
Criteria other than social/psychological 2
Strong indicators 4
Tanner stage IV or V, 95% bone growth
Strong indicators T2DM OSA Non-alcoholic steatohepatitis Pseudotumor cerebri
Adolescent gastric bypass benefit
*sleeve recommended in pediatric algorithm
56% EBW weight loss at 10 years ( EBW? )
Lower complication rates than adults, 5.5%
Pregnancy after WLS pro/cons
*wait a year after surgery, supplement folate
Reduced GDM, LGA
Increased SGA,Preterm birth, Still birth
Intragastric balloons-criteria, duration, TWL, serious AE
BMI 30-40 with comorbids Place for 6 months then remove 12% TWL at removal 10.5% incidence serious AE *trend toward weight regain after 3 years
Plenity/Gelesis 100 - % achieving 5% TBW lost at a year
33%
What is considered inadequate WL or weight regain post-bariatric surgery?
<20% WL
>15% weight gain
What percentage of people have significant weight gain within 2-5 years after surgery?
25-35%
What are the most common type of kidney stones in obese patients?
oxalate
Symptoms signs of Cu deficiency \
*can occur with Fe deficiency, as it is involved with iron metabolism
Labs 3
Imaging 1
Symptoms groupings 2
Risk factors 2
- Normocytic, MICROCYTIC anaemia
- Ringed sideroblast
- Vacuoles in some marrow
- MRI T2 imaging increased in dorsal column
Progressive sensory ataxia with spastic gait
Weakness fatigue
At risk- excess zinc intake, bariatric surgery
Gastro-gastric fistula.
When does it develop, sx
> 30 days post bypass surgery
Non healing ulcer results in opening between gastric pouch and remaining stomach.
Sx-increased capacity to ingest and absorb food, often with suboptimal weight loss or weight gain