ribosomas Flashcards

1
Q

lectinas

A

calexina y calreticulina

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2
Q

tipo de ARN subunidad menor ribosomas euca

A

18 S

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3
Q

tipo de ARN subunidad maypr ribosomas euca

A

5 S
5.8 S
28 S

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4
Q

proteínas subunidades ribosmas euca

A

menor: 33
mayor: 49

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5
Q

tipo de ARN subunidad menor ribosomas proca

A

menor: 16 S
mayor: 23 y 5 S

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6
Q

rRNA 45s

A

corta y modificado por snRNA (18, 5.8 y 28)

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7
Q

secuencia de inicio

A

AUG (metionina)

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8
Q

secuencia de terminación

A

UAG
UAA
UGA

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9
Q

destino proteínas de ribosoma en citosol

A
  1. libres
  2. membrana
  3. citoesqueleto
  4. nucleo (histonas)
  5. mitochondria, platidos, peroxisoma
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10
Q

destino proteínas de ribosoma en RE

A

Golgi + lisosomas

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11
Q

diferencias RER y membrana

A
  1. menos colesterol
  2. sin glicolipidos/esfingomielina
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12
Q

penetración proteínas al lumen del RER

A
  1. prt. comienza formación ribosoma
  2. prt. tiene peptido señal
  3. partícula de reconocimeinto del peptido señal (SRP) encuentra prt. y la lleva al RER
  4. en el RER, ribosoma libera SRP
  5. Reanuda la formación, se abre poro
  6. Liberación
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13
Q

glicosilción RER

A
  1. en el lumen, RER tranfiere oligosacaridos
  2. secuenacia aparagina - x- serina /asn-x-treonian
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14
Q

diferencia n-glicosilación y o-glisocilacón

A

n: exclusiva del RE
o: empeiza en RE, termina Golgi

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15
Q

plegamiento proteínas

A

chaperonas
1. proteína + oligosac (pierne 2 glucosas)
2. unión con lectina
3. lectina pliegue y ruemueve glucosa
4. lista para Golgi

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16
Q

si el pregamiento es reparable

A
  1. reincorporación glucosa
  2. lectina
17
Q

plegamiento irreparable

A
  1. se quitan manosas
  2. ubiquitanción