Rhinology | Flashcards
What is rhinosinusitis?
An inflammatory process involving the mucosa of the nose and sinuses
Why is the term sinusitis no longer used?
Because inflammation of the mucosa is rarely confined to the sinuses and usually affects the whole URT
What are the 3 classifications of rhinosinusitis according to its length of time?
- Acute (<4 weeks)
- Subacute (4-12 weeks)
- Chronic (>12 weeks)
Chronic rhinosinusitis is a multifactorial disease. What are some of the factors that can contribute to it? (4)
- Bacterial infection
- Allergy
- Mucociliary impairment
- Swelling of the mucosa for other reasons
Which meatus do the maxillary, frontal and anterior ethmoid sinuses drain into?
Middle meatus (between the inferior and middle turbinate)
Which meatus does the posterior ethmoids drain into?
Superior meatus
Which meatus does the sphenoid sinus drain into?
Sphenoethmoidal recess in posterior nasal cavity
Which is the most commonly affected sinus?
Maxillary
What usually precedes rhinosinusitis?
Viral URTI
What is the pathophysiology of rhinosinusitis? (3)
- URTI involves all the respiratory epithelium including the paranasal sinuses
- This causes hyperaemia and oedema of the mucosa which block sinus drainage
- Stasis of secretions predisposes to 2o bacterial infection
What are the 2 most common causal organisms of rhinosinusitis?
- Streptococcus pneumoniae
2. Haemophilus influenzae
What are the clinical features of acute rhinosinusitis?
Main (4)
Others (3)
Main symptoms:
- Follows an acute viral URTI
- Severe unilateral pain over the infected sinus
- Malaise
- Pyrexia
Others:
- Nasal obstruction
- Mucopurulent rhinorrhoea
- Poor smell
What does pain developing in the cheek or upper teeth indicate?
Maxillary sinus involvement - tends to be unilateral
What does pain above the eye and tenderness of the supraorbital margin indicate?
Frontal sinusitis
What does retro-orbital pain or pain at the vertex of the head indicate?
Sphenoid infection - but pain can be referred to temporal region or to whole head
What does tenderness on percussion of the upper first or second molar indicate?
Rhinosinusitis of dental origin
What would anterior rhinoscopy show in a patient with rhinosinusitis (2)?
- Inflamed or oedematous nasal mucosa
2. Mucopurulent secretions in nasal cavity
What could a throat examination in patient with rhinosinusitis show?
Mucopurulent secretions in the posterior oropharynx
What investigations would be done for rhinosinusitis?
Usually unnecessary
-Can do plain sinus x-ray
What are the treatments for rhinosinusitis (3)?
- Analgesia
- Steam inhalations
- Decongestant
How does the decongestant work? How long should it be used for?
Reduces nasal oedema and improves natural drainage of the sinuses
No longer than 5 days
Why should the decongestant spray not be used long-term?
To avoid rhinitis medicamentosa - nasal vasculature becomes habituated and damaged by the sympathomimetic action of the drug resulting in rebound congestion and chronic nasal obstruction
When are Abx recommended for rhinosinusitis?
In severe cases or where symptoms are persisting or progressing
What Abx is recommended for severe acute maxillary sinusitis? For how long?
Penicillin/Amoxicillin for 7-14 days
When does someone with rhinosinusitis need to be referred to an ENT surgeon (2)?
- If there is progressive pain in the sinuses - may need draining
- If signs of complications arise
What signs indicate complications of rhinosinusitis requiring immediate referral (4)?
- Periorbital cellulitis
- Severe headaches
- Focal neurological signs
- Symptoms of meningitis
What are the 3 main causative organisms of chronic rhinosinusitis?
- Staph. aureus
- Coagulase-negative staphylococcus
- Anaerobic and gram-negative bacteria
What is the pathology of chronic rhinosinusitis (5)?
- No frank purulent infection
- Mucosal hyper-reactivity to staph superantigens can lead to nasal polyps
- Hypertrophic mucosa with tenacious secretions
- At histology, the lining is replete with eosinophils
- No evidence of allergy
What are the 5 clinical features of chronic rhinosinusitis?
- Nasal obstruction
- Discoloured discharge (nasal or post-nasal) for >12 weeks
- May experience a smell disturbance (anosmia or cacosmia)
- May have intermittent frontal pain
- It is USUALLY painless
What are the 5 key points in the history of chronic rhinosinusitis?
- An exacerbation of pain during an URTI
- An association with rhinological symptoms
- Pain that is worse on flying
- Responds to medical treatment
- Longer than 12 weeks
What are possible diagnoses of facial pain or pressure on its own without nasal symptoms or signs? What is it not?
(5)
- Not rhinosinusitis
- Midfacial segment pain
- Migraine
- Cluster headaches
- Atypical facial pain
What are 4 physical signs of CRS?
- Mucosal swelling
- Inflammation
- Discharge
- Nasal polyps
How do you distinguish between nasal polyps and the inferior turbinate (2) ?
- Turbinates are red and sensitive
2. Polyps are pale, pendulousm opalescent, painless swellings
What are the principles aims of treating CRS?
Ventilate sinuses and restore mucociliary clearance
What are the treatments available for CRS (3)?
- Broad-spectrum oral Abx for at least 3 weeks such as:
Amoxycillin-clavulanate
OR Clindamycin
OR a combo of metronidazole and penicillin - Topical nasal steroids such as betamethasone drops for 2 months
- Nasal douching
How would you instruct a patient to administer nasal steroids?
Take drops while patient is lying on bed with the head upside down over the edge
When should someone with CRS be referred to ENT? What investigations would be done?
After 8 weeks of medical therapy with no improvement
-Should have nasendoscopy to confirm diagnosis
-In persistent cases that have not responded to max medical treatment, a CT scan of paranasal sinuses with a view to surgery may be considered
How do you instruct someone to perform nasal douching (4)?
- Mix 1/2 teaspoon of salt, sugar, BOS in 2 pints of boiled water which has been left to cool
- Put some on a saucer/draw up with a syringe
- Block off one nostril with one finger and then sniff or squeeze up the solution into the other nostril, letting it run out afterwards
- Topical sprays and drops should be taken after douching
What are complications of infective sinusitis (6)?
Which is the most common serious complication? *
- Chronic sinusitis
- Osteomyelitis
- Peri-orbital cellulitis and orbital abscess*
- Facial cellulitis
- Mucoceles
- Intracranial complications
- Meningitis
- Cavernous sinus thrombosis
- Brain abscesses
- Extradural abscess
- Subdural abscess
What are peri-orbital cellultis and orbital abscesses?
Direct/blood-bourne spread of infection from ethmoid sinus to the orbit as it is only separated by a thin plate of bone. It can lead to:
- Cellulitis = inflammation of skin anterior to orbital septum
- Orbital abscess whereby pus is subperiosteal but posterior to orbital septum
What is the management of peri-orbital cellulitis?
High dose Abx and careful observation
What are the dangers of an orbital abscess? How do you monitor it (3)?
Vision at risk from pressure on optic nerve
Careful monitoring of:
- Colour vision (especially red)
- Visual acuity
- Eye movements
If in doubt CT scan
What needs to be done for an orbital abscess?
Urgent drainage