Rheumatology/MSK Flashcards
1
Q
How should bisphosphonates be taken?
A
With plenty of water while sitting/standing on an empty stomach at least 30 mins before breakfast. Should sit/stand for 30 mins after taking.
2
Q
What are the possible side effects of bisphosphonates?
A
Oesophageal reactions: oesophagitis, oesophageal ulcers
Osteonecrosis of the jaw
Increased risk of atypical stress fractures
3
Q
What interaction may occur if Azathioprine and Allopurinol are taken together?
A
Interact causing bone marrow suppression
4
Q
What test should be done prior to starting Azathioprine?
A
Thiopurine methyltransferase deficiency (TPMT)
