Rheumatology antibodies Flashcards
1
Q
What histone indicate?
A
Drug induced lupus
2
Q
What does dsDNA indicate?
A
SLE and renal involvement and disease activity
3
Q
What antibodies is sjogrens associated with?
A
Anti-Ro and anti-La
4
Q
What does anti-Sm antibodies indicate?
A
SLE
5
Q
What does anti-Jo-1 indicate?
A
Polymyositis
6
Q
What does Scl 70 indicate?
A
Scleroderma
7
Q
What does RNP indicate?
A
Mixed connective tissue disease
8
Q
What does PM-Scl indicate?
A
Myositis/ Systemic sclerosis overlap
9
Q
What might c-ANCA indicate?
A
Granulomatosis with polyangitis
10
Q
What might p-ANCA indicate?
A
Eosinophilic granulomatosis with polyangitis (EGPA) or microscopic polyangitis
11
Q
In what conditions is it helpful to measure complement (C3/4)?
A
SLE, vasculitis, glomerulonephritis
12
Q
What do anti centromere antibodies indicate?
A
Systemic sclerosis
