Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Block Two - Rheum/Ortho/Anaes/ITU and A&E > Rheumatology > Flashcards

Rheumatology Flashcards

1
Q

What is the mode of action of rituximab?

A

B-cell depletor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What rheumatological conditions is rituzimab used to treat?

A

RA, SLE, CTDs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the mode of action of infliximab?

A

Anti-TNF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What rheumatological conditions is rituzimab used to treat?

A

RA, PsA, JIA, AS, PsO, Crohn’s, UC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the mode of action of tociluzimab?

A

IL-6 Inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the mode of action of iloprost? What condition is it used to treat?

A

Vasodilator; Raynauds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What side effects must be observed for with using iloprost?

A

Hypotension, arrhythmias, headaches and nausea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the mode of action of iloprost? What condition is it used to treat?

A

Ankylating agent (chemotherapy); CTDs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What drug must be given in conjunction with cyclophosphamide?

A

Mesna (chemoprotectant)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What do the biologics rituximab, infliximab, tociluzimab, iloprost and cyclophosphamide have in common?

A

They all require infusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the DMARDs commonly used in rheumatological conditions?

A

Methotrexate, sulfasalazine, hydroxychloroquine and leflunomide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What DSA score constitutes qualifying for bioloigic therapy in RA?

A

> 5.1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What constitutes qualifying for bioloigic therapy in PsA?

A

Three sore joints and three swollen joints

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the BASDAI

A

Bath Ankylosing Spondylitis Disease Activity Index

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the Spinal VAS?

A

Visual Analogue Scale for pain in SpA cases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What qualifies use of biologics in SpA?

A

BASDAI and Spinal VAS >4

17
Q

What investigations are required before commencement of biologic therapy?

A

TB status
Hep B and C
HIV
Vericella/Shingles

18
Q

List five self-infection biologics available

A 
Entanercept
Adalimumab
Certolizumab 
Golimumab 
Abatacept
19
Q

What is important about certolizumab?

A

It is safe during pregnancy

20
Q

What supplement must be taken if on methotrexate?

A

Folate

Block Two - Rheum/Ortho/Anaes/ITU and A&E (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions