Rheumatology

Question 1

Name the four major Rheumatoid factor Seronegative conditions

Answer 1

Think SPEAR (S is for seronegative)
P - Psoriatic Arthritis
E - Enteropathic Arthritis
A - Ankylosing Spondylitis
R - Reactive Arthritis (post infection) - AKA Reiter's syndrome - can't see, can't pee, can't bend one knee (conjunctivitis, urethritis, arthritis).

Question 2

Name the two major crystal arthropathies

Answer 2

Gout

Pseudogout

Question 3

Name the major rheumatoid factor seropositive arthropathy.

Answer 3

Rheumatoid Arthritis

Question 4

Name the four things common to all seronegative Arthritis conditions (other than the fact they are rheumatoid factor negative).

Answer 4

(1) Associated with the HLA-B27 gene
(2) Sacroileitis
(3) Enthesitis (inflammation where tendons insert into bone - classically at the Achilles’ tendon)
(4) Extra-articular features different to rheumatoid arthritis - Anterior Uveitis

Question 5

Which joints are typically affected by Ankylosing Spondylitis?

Answer 5

Spinal and Sacroiliac joints

Question 6

Name the two extra-articular manifestations of rheumatoid arthritis in the specialty of Ophthalmology

Answer 6

Epic Letitia

Dry eyes

Question 7

Name the three extra-articular manifestations of rheumatoid arthritis in the specialty of Respiratory Medicine

Answer 7

Pulmonary Fibrosis (both pathological and methotrexate induced)
Rheumatoid Pulmonary Nodules
Pleural Effusion

Question 8

Name the three extra-articular manifestations of rheumatoid arthritis in the specialty of Cardiovascular Medicine

Answer 8

Pericardial effusion
Pericarditis
Ischaemic Heart Disease (IHD)

Question 9

Name the main extra-articular manifestation of rheumatoid arthritis in the specialty of Gastrointestinal Medicine

Answer 9

Hypersplenism

Question 10

Name the two extra-articular manifestations of rheumatoid arthritis in the specialty of Haematology

Answer 10

Anaemia of chronic disease

Lymphadenopathy

Question 11

Name the main extra-articular manifestation of rheumatoid arthritis in the specialty of Musculoskeletal Medicine

Answer 11

Carpal Tunnel Syndrome

Question 12

Name the main extra-articular manifestation of rheumatoid arthritis regarding vasculitis

Answer 12

Haematuria

Question 13

Name the four findings on a hand X-ray of a Rheumatoid Arthritis patient.

Answer 13

Think LESS
L - Loss of joint space
E - Erosions of the bone
S - subluxation of the PROXIMAL phalanges
S - see-through bones (osteopenia)