Rheumatology Flashcards
Joint pain as a result of rheumatic diseases is called:
A. morning stiffness
B. myalgia
C. arthralgia
D. arthritis
E. arthrosis
C. arthralgia
Typical symptoms and signs of rheumatic diseases are ALL EXCEPT:
A. swollen and painful joints
B. tachycardia
C. muscle pain
D. morning stiffness of the joints
E. elevated body temperature
B. tachycardia
Which of the following diseases does not manifest with elevated body temperature?
A. systemic lupus erythematosus
B. granulomatosis with polyangiitis (Wegener`s granulomatosis)
C. giant-cell arteritis
D. reactive arthritis
E. arthrosis
E. arthrosis
Life-threatening diseases in rheumatology that directly affect life are:
A. rheumatoid arthritis, spondylitis ankylosis
B. granulomatosis with polyangiitis (Wegener`s granulomatosis), polyarteritis
nodosa
C. giant-cell arteritis
D. systemic lupus
B. granulomatosis with polyangiitis (Wegener`s granulomatosis), polyarteritis
nodosa
D. systemic lupus
Raynaud`s phenomena:
A. the skin of the fingers turns pale/white at first, then blue and at the end red
B. the skin of the fingers turns pale/white at first, then red and at the end blue
C. the skin of the fingers turns red at first, then blue and pale/white at the end
D. the skin of the fingers turns red at first, then pale/white and blue at the end
E. the skin of the fingers turns blue at first, then red and pale/white at the end
A. the skin of the fingers turns pale/white at first, then blue and at the end red
Too frequent hair fall is typical for
a. systemic lupus erythematosus
b. arthrosis
c. giant cell arteritis
d. IgA vasculitis (purpura Henoch-Shoenlein)
a. systemic lupus erythematosus
Dryness of the eye conjuctiva, mouth mucosa and vagina is typical for
a. systemic lups erythematosus
b.Sjorgen’s syndrome
c. Giant cell arteritis
d. poliarteritis nodosa
e. gout
b.Sjorgen’s syndrome
Ulci on nose mucosa and persistent nasal discharge are typical for
a. systemic lupus erythematosus
b. granulomatosis with polyangiitis (Wegener’s granulomatosis)
c. Giant cell arteritis
d. Ankilizirajoči spondylitis
e. Polymyositis and dermatomyositis
b. granulomatosis with polyangiitis (Wegener’s granulomatosis)
If the patient mentions spontaneous abortion or stillbirth, we should think of
A. Lyme disease
B. antiphospholipid syndrome
C. eosinophilic granulomatosis with polyangiitis (Churg Strauss syndrome)
D. IgA vasculitis (purpura Henoch-Shoenlein)
E. Systemic Sclerosis
B. antiphospholipid syndrome
During joint examination we use of the rules 5P. This means:
A. to look, feel, move, measure, compare with the opposite side
B. to look, feel, knock, move, compare with the opposite side
C. to look, feel, knock, listen, move
D. to look, feel, knock, listen, compare with the opposite side
E. to look, feel, move, listen, measure
A. to look, feel, move, measure, compare with the opposite side
Swollen and hot joint is the result of
a. active synovitis as a part of rheumatic disease
b. infection
c. crystal-induced arthritis
d. polymyalgia rheumatica
e. arthrosis
a. active synovitis as a part of rheumatic disease
b. infection
c. crystal-induced arthritis
Muscle atrophy: connect the cause and effect
A. interosseal muscle atrophy on hands is characteristic for carpal tunnel syndrome. Atrophy
of the quadriceps is characteristic for arthritis of small joints in rheumatoid arthritis. Atrophy
of thumb bundle is characteristic for chronic arthritis of the knee.
B. interosseal muscle atrophy on hands is characteristic for carpal tunnel syndrome. Atrophy
of the quadriceps is characteristic for chronic arthritis of the knee. Atrophy of thumb bundle is
characteristic for arthritis of small joints in rheumatoid arthritis.
C. interosseal muscle atrophy on hands is characterized by arthritis of the small joints in
rheumatoid arthritis. Atrophy of the quadriceps is typical for carpal tunnel syndrome. Atrophy
of thumb bundle is characteristic for chronic arthritis of the knee.
D. interosseal muscle atrophy of hands is characteristic for arthritis of the small joints in
rheumatoid arthritis. Atrophy of the quadriceps is characteristic for chronic arthritis of
the knee. Atrophy of thumb bundle is characteristic for carpal tunnel syndrome.
E. interosal muscle atrophy of hands is characteristic for chronic arthritis of the knee. Atrophy
of the quadriceps is typical for carpal tunnel syndrome. Atrophy of thumb bundle is
characteristic for arthritis of small joints in rheumatoid arthritis.
D. interosseal muscle atrophy of hands is characteristic for arthritis of the small joints in
rheumatoid arthritis. Atrophy of the quadriceps is characteristic for chronic arthritis of
the knee. Atrophy of thumb bundle is characteristic for carpal tunnel syndrome.
Morning stiffness:
A. feature of arthrosis is morning stiffness that lasts 1-4 hours
B. Patient can shorten morning stiffness with massaging the joint with ice
C. morning stiffness of knee and shoulder is characteristic for early rheumatoid arthritis
D. strong morning stiffness is characteristic for polymyalgia rheumatica and rheumatoid
arthritis
E. morning stiffness is most effectively treated with antibiotics
D. strong morning stiffness is characteristic for polymyalgia rheumatica and rheumatoid
arthritis
We often see Livedo reticularis in the context of:
A. Antiphospholipid syndrome and polyarteritis nodosa,
B. Sjogren’s syndrome
C. fibromyalgia and giant arteritis
D. rheumatoid and psoriatic arthritis
E. Lyme disease
A. Antiphospholipid syndrome and polyarteritis nodosa,
The most common reason for the monoarthritis
A. rheumatoid arthritis and spondyloarthritis
B. joint infection and crystal-induced arthritis
C. systemic connective tissue diseases and vasculitis
D. joint infection and systemic connective tissue diseases
E. rheumatoid arthritis, and crystal-induced arthritis
B. joint infection and crystal-induced arthritis
Which statements are correct for HEP-2 test?
a) in the case of a positive result we can confirm autoimmune disease with absolute certainty
b) we observe the positive reaction of potentially present autoantibodies in the nucleus at
the time of division, in nucleoli and cytoplasm
c) is usually the first screening test for autoantibodies in the diagnosis of autoimmune
diseases
d) in overlapping syndromes the test is usually negative
b) we observe the positive reaction of potentially present autoantibodies in the nucleus at
the time of division, in nucleoli and cytoplasm
c) is usually the first screening test for autoantibodies in the diagnosis of autoimmune
diseases
Which statements are correct for antinuclear antibodies -ana:
a) it is a part of the HEP-2 test
b) ANA is often positive in patients with systemic lupus erythematosus, Sjögren’s
syndrome and systemic sclerosis
c) titer of ANA modifies with the activity of autoimmune diseases
d) ANA titer 1:80 or less is irrelevant in the absence of symptoms
a,b,d
As a screening test for the detection of autoantibodies we use
A. ESR
B. the concentration of C-reactive protein
C. investigation on the cellular substrate HEp-2 and anti-ENA
D. investigation of anti-ds-DNA
E. investigation antineutrophil antibodies (ANCA) and anti endomysium antibodies (EMA)
C. investigation on the cellular substrate HEp-2 and anti-ENA
As a first screening test for the presence of autoantibodies in rheumatology we use:
A. ACPA
B. anti-dsDNA
C. anticardiolipin antibodies (aCL)
D. HEP-2 test
E. Antineutrophil antibodies (ANCA)
D. HEP-2 test
In the case of suspected systemic connective tissue disease, the result of ANA 1:40 is:
A diagnostic, the patient certainly has one of the systemic connective tissue diseases
B. diagnostic, but only for systemic lupus erythematosus. In other systemic diseases
connective tissue diseases ANA are not always present
C. extremely susceptible, the likelihood of systemic disease is at least 80 percent content
D. diagnostic for one of the systemic connective tissue diseases, but only if the patient has
also elevated ESR.
E. such a result is obtained in 30% of healthy individuals, therefore the diagnostic value
of this result is negligibly small
E. such a result is obtained in 30% of healthy individuals, therefore the diagnostic value
of this result is negligibly small
Antinuclear antibodies may be found in
a. patients with inflammatory rheumatic disease
b. patients with autoimmune thyroiditis
c. patients with chronic infections
d. cancer patients
e. healthy pregnant women and the elderly
All
Which statements are correct for HEP-2 test?
A. we use neutrophilic granulocytes for he substrate
B. With this test we can detect autoantibodies against antigens of the nucleus during
division, cells in division and cytoplasm
C. with this test we can detected autoantibodies against the Fc part of immunoglobulin G
D. In the case of a negative result we can certainly exclude autoimmune disease
E. the test is always negative in healthy subjects
B. With this test we can detect autoantibodies against antigens of the nucleus during
division, cells in division and cytoplasm
Which statements are correct for ANA test?
a) it is the part of HEp-2 test
b) we evaluate antibodies quantitavely and express them with titer
c) A negative result means that neither in the core nor in the cytoplasm do not see
florescence
d) in patients with inflammatory rheumatic disease, ANA titers of 1:80 or lower
e) ANA titer compared to the activity of the disease varies
a) it is the part of HEp-2 test
b) we evaluate antibodies quantitavely and express them with titer
c) A negative result means that neither in the core nor in the cytoplasm do not see
florescence
Antibodies against pyruvate dehydrogenase complex (anti-PDH) are the most specific for
A. Primary biliary cirrhosis
B. Rheumatoid Arthritis
C. Hashimoto thyroiditis
D. gout
E. Giant cell arteritis
A. Primary biliary cirrhosis